Protein Alignment CG43373 and CG31183

DIOPT Version :9

• Sequence 1: NP_001097622.2
• Gene: CG43373 / 39835
• FlyBaseID: FBgn0263131
• Length: 1854
• Species: Drosophila melanogaster
• Sequence 2: NP_001287342.1
• Gene: CG31183 / 41927
• FlyBaseID: FBgn0051183
• Length: 1417
• Species: Drosophila melanogaster
• Alignment Length: 1631
• Identity: 320/1631 - (19%)
• Similarity: 546/1631 - (33%)
• Gaps: 543/1631 - (33%)

  Fly   397 KHRYK-------HKSHQ----QHRTRYRMREKRSLQDAGLVKGGGIQTQLIVDTATDDDADVYTV 450
            :|.:|       |||..    ||.....|.:.|.|         |.:.||:.      .|.:.:|
  Fly    46 EHSFKTPETKNSHKSQSTELVQHFPSLPMPDHRRL---------GARRQLVF------VALLPSV 95

  Fly   451 ASDDDDD----------------VDGGRSAGSKHITYTPRVRDYNQISHAERDEVLNTSSNAGVA 499
            .||:.:|                |......|..|.       |...||   ||..  .||..|
  Fly    96 ESDNKNDCIMPKVLPVLELAIRHVQRMGFVGGSHF-------DIQLIS---RDTF--CSSKYG-- 146

  Fly   500 TDNSDPPLGYGQLIPLILMQVDESVLVFLIVMLICGIVYAFLLCILSKPAMNEIFLVLV------ 558
                  |:|:.:    |..|..|...||       |:...::|..:|:.|  :::.|.|
  Fly   147 ------PIGFFE----IYTQWPEVNAVF-------GLPCEYVLAPISRYA--DVWQVPVLTTGGN 192

  Fly   559 ---------SY-------------------VILGTFLAIEVAVSYAMQPSKSFNGSAC--CIVLI 593
                     ||                   .||.:|.....|:.|..:.:|....|.|  |:..|
  Fly   193 AKEFNKKSESYSTLTRLKGAQVNNLGNVVRAILNSFNWTRTALIYQNENAKVKGNSVCFLCLAAI 257

  Fly   594 YMT---YTMLPLRL-----REALIGGILLSVVHLYTCLRLNAMQDEAVEMI----HWEELLCTLV 646
            :.|   :::..|..     .:|.|..:|.:|          |||...|.|.    ...:::.|..
  Fly   258 HDTIEEHSVYQLGFDTSTWTKADITRMLKNV----------AMQSRIVIMCADPQSIRQIMLTAE 312

  Fly   647 ALLLANLTGVYTHWPKEKAQRKAFIETRQCIEARLRTQRENQQQER---LLLSVLPRHVAMEMKD 708
            .|.:.: :|.|.....|...|..:: |.|....:..|...|::.::   .:|:|.|:
  Fly   313 ELNMID-SGEYVFINIELFSRVQYL-TSQPWYDKNDTDLNNERAQKAYTAMLTVTPK-------- 367

  Fly   709 DIAGQPRDTQF----HKIYIQRHENVSILFAD---ICGF-----------------------TSL 743
                ||.|.::    ::|.....|..:..|:|   |..|                       |.|
  Fly   368 ----QPNDNEYTRVSNEIKAIAAEKYNYTFSDNEPISAFVTSFFDGVLLYANALNESIREDPTML 428

  Fly   744 SDQCTAEELV-RLLNELF----------ARFDRLAAE-------------------HHCLRIKLL 778
            :......::| |:.|..|          |..|||:|.                   |:.|..:..
  Fly   429 TRPINGTDMVRRMWNRSFTGITGNVTIDANGDRLSAYSLLDMNPTTGRFEIVAHFLHNRLEFEAN 493

  Fly   779 GDCYYCVSGLPEPRPDHAHCAVEMGL---DMIDAIALVREVM-AVNVNMRVGIHTGRVHC---GV 836
            .:.:: .....|..||...|..:..|   :.:...|::..|: .:.|.|.|....|..|.   ..
  Fly   494 KEIHW-AGDREEAPPDRPICGYDGALCPDNSLPGYAILSIVLGTMVVVMAVCFFFGYRHYIAEAE 557

  Fly   837 LGLVKWQFDVWSNDVTLANHMESGGIPGRVH----------ITKETLKCLDGDYEVEVGKGNERN 891
            :..:.|:..:  .||...:..|. |:.|..|          :..|.:..::||.::
  Fly   558 INSMSWKVSL--EDVMFRDAAER-GLRGSFHSLVKQSSQLTLMSEDMVSINGDRQI--------- 610

  Fly   892 SYLKDHQIETYLIVPGDIYRPHKKSRNRLQVNG-------NISKELRMMGHGTAQKHTSKFGFGD 949
                        .:|..::|..|.:...::|:.       ::..||:.| ......|..|| :|.
  Fly   611 ------------FIPVGMFRKSKVAIKPVEVDNVQGLLTRSLMLELKRM-KDLQHDHLVKF-YGA 661

  Fly   950 SSESAKD-------PEDEVNEYL-------------------------MRAIDARSIDHLRAEHC 982
            ..:..:.       |:..:.:.|                         :.:.|.||..:|::.:|
  Fly   662 CLDQRRSFLLTEYCPKGSLQDILENEQFQLDWMFRLSLMHDIVRGMQFLHSSDIRSHGNLKSSNC 726

  Fly   983 ---QSLLLCFKD---NVLER-KYASEPDRMLC-VYFYCSLLVLLGTSIMRLVVFQSSLLTLALST 1039
               ...:|...|   :.|.| ::..|.|...| .:.|.|.|:.....::|:   :.:........
  Fly   727 VVDSRFVLKITDFGLHTLRRTRFDLESDGGNCNSHAYWSKLLWTAPELLRV---EHNRPPEGTQK 788

  Fly  1040 GALLLLGFLVFLVACHKINFQL--------PSDIKRFSLRIHSNRRISQLFAFASVALIVLTTLL 1096
            |.:...|.:|..:...:..|.|        |.:|... ::.::..|:.:.|
  Fly   789 GDVYAFGIIVHEITTRQGPFYLGRCAYEKSPQEIIEL-VKGYNPHRMQKPF-------------- 838

  Fly  1097 AMFQESGRQMELLQRRRFWLDVNGSISLNDTELNTKMYDAEEPDCDFYLAYNTFLLLTLLSMMSC 1161
                    :.||........|:||.|.....|     ..||.||      :||...:........
  Fly   839 --------RPELEPNGDTKADINGIIRRCWAE-----DPAERPD------FNTLKSMIRRFNKDN 884

  Fly  1162 ATYQVLRILLKLLLLLLASGSYMACSSNLYSRSREMSQELANEEALLRYIIDSIFLFAFMLALIF 1226
            .|..::..|||.:.|.         ::||.....|.:|:                         :
  Fly   885 ETGNIVDNLLKRMELY---------ANNLEELVEERTQD-------------------------Y 915

  Fly  1227 HSHQTEATYRLDFIWKLQATEEKEDMEHLQAYNRKLLENILPVHVAEHFLSREKHLDDLYHEQCD 1291
            |                   |||:..|       |||..:||..||...:|.:    .:..|..|
  Fly   916 H-------------------EEKKKCE-------KLLYQLLPQSVAAQLISGQ----PVVAETFD 950

  Fly  1292 SVCILFASIPNFSEFYVELEGNNEGVECLRLLNEIIADFDELLSEERFRCIEKIKSTGATYMAAS 1356
            .|.|.|:.|..|:....|    :..::.::.||::...||.::  |.|. :.|:::.|..||..|
  Fly   951 QVTIYFSDIVGFTAISAE----STPMQVVQFLNDLYTCFDSIV--ENFD-VYKVETIGDAYMVVS 1008

  Fly  1357 GLTANTCDRVNFSHVTAMADYALQLFDKIEEVNMH--SFNNFRMRIGINIGPVVAGVIGACKPQY 1419
            ||..    |....|...:|..||.|.:.:....:|  ..:..::|||::.|..||||:|...|:|
  Fly  1009 GLPI----RNGNQHAREIARLALALLEAVHNFRIHHRPEDRLKLRIGLHTGACVAGVVGLKMPRY 1069

  Fly  1420 DIWGNAVNVASRMDSTGLVDHIQVTQEMQQILEGRG-FELTCRGSVDVKGKGSMITYFLKGRRPI 1483
            .::|:.||.||||:|.|....|.:::..::.|:..| |..|.||.|.:||||.|:||:|:|
  Fly  1070 CLFGDTVNTASRMESNGEALKIHISETTKEALDEFGTFVTTRRGFVPMKGKGEMLTYWLEG---- 1130

  Fly  1484 DAKELELAKTEVEPPKTL----TLAKEPEKLDSGTATEKQREQVKEQGSTEQEDDLLPSPDIDM- 1543
               |:....:.:.|.|.:    :..|:|::..|....::..|.|......:     ||.|.|.:
  Fly  1131 ---EVPRPNSLISPSKLMLTRRSSLKQPQRSQSHNLHKQYSELVVASPPPQ-----LPPPAIALP 1187

  Fly  1544 -----NSNMQNLTAQRRKSLCRQHNISSSFGTTVSSSTGITPSISNSSSVVTIGALPAILRGGNP 1603
                 :.:..||..:|:                          ||:||        |.:..||..
  Fly  1188 PPPSPSKDSPNLRVKRK--------------------------ISSSS--------PKLNGGGFD 1218

  Fly  1604 LSNANPNATDSCS----ECG-GASKSLATPTAPPRTLVADLKD-----EIARDEKIGLKDSIENL 1658
            ......:..|:.:    .|. .:|:||           .|:::     |:|. .::.|..::::.
  Fly  1219 YHKTENHYLDTAAAAQRNCDIYSSRSL-----------RDMEETSDSWELAH-FRLPLSGALKSH 1271

  Fly  1659 EILLKNNISLSDLSNKQQQNLRG----ETSSSTTTTLRKRDTIVSFNVTETVTTTA--------A 1711
            ..|  ||.|...:.:....||.|    .......|.|:...||      .|:.|:|        .
  Fly  1272 HHL--NNNSHGYVHSNSSSNLSGILQPPPLGVQRTRLKPSPTI------STLLTSARSEANASPG 1328

  Fly  1712 PFTSSSGSSNSSSQQKKRRSVTTIAASFTTSTTTRLLSNES--------QSSTQTAPGTLESGGS 1768
            |.|.|.||..             :...|.....|.||....        ......:|....||.:
  Fly  1329 PETGSMGSGQ-------------LRIKFAEGDETPLLPTPPPLAAPPPIPQMVAASPQRSGSGQN 1380

  Fly  1769 VPGQSS 1774
            :|..||
  Fly  1381 IPADSS 1386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43373	NP_001097622.2	AC_N	<523..720	CDD:292831	47/251 (19%)
		CYCc	686..881	CDD:214485	48/274 (18%)
		Guanylate_cyc	722..895	CDD:278633	41/245 (17%)
		DUF1053	<949..1005	CDD:283888	13/94 (14%)
		CYCc	1259..1455	CDD:214485	58/197 (29%)
		Guanylate_cyc	1285..1479	CDD:278633	64/196 (33%)
CG31183	NP_001287342.1	PBP1_NPR_like	88..498	CDD:107368	87/472 (18%)
		ANF_receptor	108..473	CDD:279440	80/421 (19%)
		PK_GC-A_B	589..883	CDD:270944	54/353 (15%)
		Pkinase_Tyr	613..877	CDD:285015	51/302 (17%)
		HNOBA	<893..938	CDD:285003	20/104 (19%)
		CYCc	917..1108	CDD:214485	63/212 (30%)
		Guanylate_cyc	944..1130	CDD:278633	64/196 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453953
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740