DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG43373 and AGO1

DIOPT Version :9

Sequence 1:	NP_001097622.2	Gene:	CG43373 / 39835	FlyBaseID:	FBgn0263131	Length:	1854	Species:	Drosophila melanogaster
Sequence 2:	NP_001246314.1	Gene:	AGO1 / 36544	FlyBaseID:	FBgn0262739	Length:	984	Species:	Drosophila melanogaster

Alignment Length:	413	Identity:	80/413 - (19%)
Similarity:	130/413 - (31%)	Gaps:	114/413 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly  1225 IFHSHQTEATYRLDFIWKLQATEEKEDMEH--LQAYNRKLLENILPVHVAEHFLS------REKH 1281
            |.|..|....||:     ...|.....|:.  ||..|.:.:|    ..||::||.      |..|
  Fly   378 ITHCGQMRRKYRV-----CNVTRRPAQMQSFPLQLENGQTVE----CTVAKYFLDKYRMKLRYPH 433

  Fly  1282 LDDLYHEQCDSVCILFASIPNFSEFYVELEGNN--EGVECLRLLNEIIADFDELLSEERFRCIEK 1344
            |..|...|            .....|:.||..|  .|..|::.|.::             :....
  Fly   434 LPCLQVGQ------------EHKHTYLPLEVCNIVAGQRCIKKLTDM-------------QTSTM 473

  Fly  1345 IKSTGATYMAASGLTANTCDRVNFSHVTAMADYALQLFDKIEEVNMHSFNNFRMRIGINIGPVVA 1409
            ||:|..:.........|...|.:|::.:.:.::.|.:.:.:.||........:::.|   |.|..
  Fly   474 IKATARSAPDREREINNLVKRADFNNDSYVQEFGLTISNSMMEVRGRVLPPPKLQYG---GRVST 535

  Fly  1410 GVIG-----------ACKPQYDIWGNAVNVASRMDSTGLVDHI------------------QVTQ 1445
            |:.|           ...|...:|    ::..:...||:...|                  ..||
  Fly   536 GLTGQQLFPPQNKVSLASPNQGVW----DMRGKQFFTGVEIRIWAIACFAPQRTVREDALRNFTQ 596

  Fly  1446 EMQQILEGRGFELT-----CRGSVDVKGKGSMITYFLKGRRPIDAKELELAKTEVEPPKTLTLAK 1505
            ::|:|....|..:.     |:.:........|..| ||    |....|:|. ..|.|.||...|:
  Fly   597 QLQKISNDAGMPIIGQPCFCKYATGPDQVEPMFRY-LK----ITFPGLQLV-VVVLPGKTPVYAE 655

  Fly  1506 EPEKLDSGTATEKQREQVKEQGSTEQEDDLLPSPDIDMNSNMQNLTAQRRKSLCRQHNISSSFGT 1570
            .....|:......|..|.|                     |:...:.|...:||.:.|:... |.
  Fly   656 VKRVGDTVLGMATQCVQAK---------------------NVNKTSPQTLSNLCLKINVKLG-GI 698

  Fly  1571 TVSSSTGITPSISNSSSVVTIGA 1593
            .......|.|.:.| ..|:.:||
  Fly   699 NSILVPSIRPKVFN-EPVIFLGA 720

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG43373	NP_001097622.2	AC_N	<523..720	CDD:292831
		CYCc	686..881	CDD:214485
		Guanylate_cyc	722..895	CDD:278633
		DUF1053	<949..1005	CDD:283888
		CYCc	1259..1455	CDD:214485	41/232 (18%)
		Guanylate_cyc	1285..1479	CDD:278633	37/229 (16%)
AGO1	NP_001246314.1	ArgoN	146..275	CDD:406799
		ArgoL1	285..335	CDD:400854
		PAZ_argonaute_like	336..456	CDD:239212	24/98 (24%)
		Piwi_ago-like	502..942	CDD:240015	47/255 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	0	0.000