DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG43373 and Gucy2f

DIOPT Version :9

Sequence 1:NP_001097622.2 Gene:CG43373 / 39835 FlyBaseID:FBgn0263131 Length:1854 Species:Drosophila melanogaster
Sequence 2:NP_001007577.1 Gene:Gucy2f / 245650 MGIID:105119 Length:1108 Species:Mus musculus


Alignment Length:284 Identity:88/284 - (30%)
Similarity:140/284 - (49%) Gaps:47/284 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   680 RLRTQR---ENQQQERLLLSVLPRHVAMEMKDDIAGQPRDTQFHKIYIQRHENVSILFADICGFT 741
            |.||:.   |.|:.|:||..:||..||..:|.....:|          :..:.|::.|:||.|||
Mouse   840 RERTEELEIEKQKTEKLLTQMLPLSVAESLKKGCTVEP----------EGFDLVTLYFSDIVGFT 894

  Fly   742 SLSDQCTAEELVRLLNELFARFDRLAAEHHCLRIKLLGDCYYCVSGLPEPRPDHAHCA--VEMGL 804
            ::|......|:|.|||:|:..||.:...|...:::.:||.|...||||: |....|.|  ..|.|
Mouse   895 TISAMSEPIEVVDLLNDLYTLFDAIIGSHDVYKVETIGDAYMVASGLPK-RNGSRHAAEIANMSL 958

  Fly   805 DMIDAIAL--VREVMAVNVNMRVGIHTGRVHCGVLGLVKWQFDVWSNDVTLANHMESGGIPGRVH 867
            |::.::..  :|.:..|.|.:|:|:|:|.|..||:||...::.::.:.|..|:.|||.|:|.|:|
Mouse   959 DILSSVGTFKMRHMPEVPVRIRIGLHSGPVVAGVVGLTMPRYCLFGDTVNTASRMESTGLPYRIH 1023

  Fly   868 ITKET---LKCLDGDYEVEV-------GKGNERNSYLKDHQIETYLIVPGDIYRPHKKSRNR-LQ 921
            ::..|   |:.|...||||:       |||.|          ||:.:|       .||...: |.
Mouse  1024 VSLSTVTILQTLSEGYEVELRGRTELKGKGTE----------ETFWLV-------GKKGFTKPLP 1071

  Fly   922 VNGNISKELRMMGHGTAQKHTSKF 945
            |...:.|: ..:|||......:.|
Mouse  1072 VPPPVGKD-GQVGHGLQPAEIAAF 1094

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG43373NP_001097622.2 AC_N <523..720 CDD:292831 14/42 (33%)
CYCc 686..881 CDD:214485 65/201 (32%)
Guanylate_cyc 722..895 CDD:278633 62/186 (33%)
DUF1053 <949..1005 CDD:283888
CYCc 1259..1455 CDD:214485
Guanylate_cyc 1285..1479 CDD:278633
Gucy2fNP_001007577.1 PBP1_sensory_GC_DEF-like 54..435 CDD:380594
PKc_like 545..815 CDD:419665
HNOBA <824..869 CDD:400168 12/28 (43%)
CYCc 848..1040 CDD:214485 65/202 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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