Protein Alignment CG43373 and gcy-19

DIOPT Version :9

• Sequence 1: NP_001097622.2
• Gene: CG43373 / 39835
• FlyBaseID: FBgn0263131
• Length: 1854
• Species: Drosophila melanogaster
• Sequence 2: NP_001348702.1
• Gene: gcy-19 / 191650
• WormBaseID: WBGene00001544
• Length: 1187
• Species: Caenorhabditis elegans
• Alignment Length: 602
• Identity: 123/602 - (20%)
• Similarity: 234/602 - (38%)
• Gaps: 149/602 - (24%)

  Fly   464 AGSKHITYTPRVRDYNQIS-----HAERDEVLNTSSNAG--VATDNSD----PPLGYGQLIPLIL 517
            :|..:||.|.::...|..|     :.:::.||:|:..|.  :.||...    ..|.:..:...:.
 Worm   575 SGPSNITDTSKMTFDNTFSNYSIFYLDKEPVLSTAHPASNLIRTDYDTFVRLRKLDHENVNKFVG 639

  Fly   518 MQVDESVLVFLIVMLIC--------------GIVYAFLLCILSKPA-----MNEIFLVLVSYVIL 563
            |.:|..  .:|.|..:|              .|...|:.|::...|     ::..||.:.:.:..
 Worm   640 MSIDGP--EYLAVWKLCMRGSLQDIIGQGNFSIDPFFMFCVIRDMAEGLKYLHNSFLHVHANLRS 702

  Fly   564 GTFLAIE--------VAVSYAMQPSKSFNGSACCIVLIYMTYTMLPLRLRE-------ALIGGIL 613
            ||.|..|        ..:....:..|........:....:..|:||.::.:       |:|...:
 Worm   703 GTVLVNESWQAKLTDFGLGTLAEEKKPMKRRQLWMAPEVIRGTLLPHQIEKSADIYSLAVIASEV 767

  Fly   614 LSVVHLYTCLRLNAMQDE--------------------AVEMIH---------WEE--------- 640
            |:....:.........||                    .||:.|         |.|
 Worm   768 LTRKEAWNMAERKDTVDEIVYRIKKGGPNAPRPELDMDGVEINHNLLILIRDCWSEEPADRPSAD 832

  Fly   641 LLCTLVALLLA----------NLTGVYTHWPKEKAQRKAFIETRQCIEARLRTQR---ENQQQER 692
            ::|.|:..::.          |:...||              |...:|...||:.   |.::.:.
 Worm   833 VICNLLKNMMPKKGNLMDHVFNILEDYT--------------TNLEVEVEDRTKELTAEKKKADV 883

  Fly   693 LLLSVLPRHVAMEMKDDIAGQPRDTQFHKIYIQRHENVSILFADICGFTSLSDQCTAEELVRLLN 757
            ||..:||:.||..:|.....:|          :..::|::.|:|:..||.|:.:|:..::|.|||
 Worm   884 LLGRMLPKQVAERLKQGQTVEP----------EGFDSVTVFFSDVVKFTQLAAKCSPFQVVNLLN 938

  Fly   758 ELFARFDRLAAEHHCLRIKLLGDCYYCVSGLPEPRPD-HAHCAVEMGLDMIDAIA------LVRE 815
            :|::.||.:..||.|.:::.:||.|.||||||....: |....||:.||.:....      |.||
 Worm   939 DLYSNFDAIIEEHGCYKVESIGDGYLCVSGLPSKNGNAHIKQIVELSLDFMSYCKSFKIPHLPRE 1003

  Fly   816 VMAVNVNMRVGIHTGRVHCGVLGLVKWQFDVWSNDVTLANHMESGGIPGRVHITKETLKCLDGDY 880
                .|.:|:|:::|....||:||...::.::.:.|..|:.|||.|....:|::..:...|...|
 Worm  1004 ----KVELRIGVNSGPCVAGVVGLSMPRYCLFGDTVNTASRMESNGKASHIHLSAASYTLLMKHY 1064

  Fly   881 EVEVGKGNERNSYLKDHQI-ETYLIVPGDIYRPHKKSRNRLQVNGNISKELRMMGHGTAQKHTSK 944
            ..:....:..:..:|...: ||:.:        .:::...:.|:.|       .|:.:.:|.|:.
 Worm  1065 PNQYNTASRGDVIIKGKGVMETFWV--------FERNNQFMGVSSN-------SGYQSDKKATNN 1114

  Fly   945 FGFGDSSESAKDPEDEV 961
            ....:|:..:..|..||
 Worm  1115 GSSPESTPPSTPPMHEV 1131

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43373	NP_001097622.2	AC_N	<523..720	CDD:292831	45/281 (16%)
		CYCc	686..881	CDD:214485	59/201 (29%)
		Guanylate_cyc	722..895	CDD:278633	51/179 (28%)
		DUF1053	<949..1005	CDD:283888	4/13 (31%)
		CYCc	1259..1455	CDD:214485
		Guanylate_cyc	1285..1479	CDD:278633
gcy-19	NP_001348702.1	PBP1_NPR_GC_like	45..467	CDD:107347
		PKc_like	571..841	CDD:328722	44/267 (16%)
		CYCc	876..1065	CDD:214485	59/202 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810