Protein Alignment CG43373 and gcy-32

DIOPT Version :9

• Sequence 1: NP_001097622.2
• Gene: CG43373 / 39835
• FlyBaseID: FBgn0263131
• Length: 1854
• Species: Drosophila melanogaster
• Sequence 2: NP_506452.5
• Gene: gcy-32 / 179887
• WormBaseID: WBGene00001552
• Length: 684
• Species: Caenorhabditis elegans
• Alignment Length: 512
• Identity: 124/512 - (24%)
• Similarity: 212/512 - (41%)
• Gaps: 162/512 - (31%)

  Fly   444 DADVYTVASDDDDDVDGGRSAGSKHITYTPRVRDY-----NQISHAERD----EV-LNTSSNA-- 496
            |.|:..|..        ||:..|.|:....||.::     |.:|...||    || |.||:||
 Worm   160 DLDITLVVQ--------GRTQRSVHMNNGERVEEHVVFLINNLSEPRRDSEGSEVSLLTSTNANF 216

  Fly   497 --------GVATDNSDPPLGY--------------GQL---IPLILMQVDESVL-VFLI----VM 531
                    |::.|:....|.|              .:|   ||..|:|....:| :|.|    :.
 Worm   217 PTIVDDTLGISLDDFSKALPYHFVIDESCKLVQCGSELHNHIPNELLQPGTPILRIFEINRPQIP 281

  Fly   532 L----ICGIVYA-FLLCILSKP------------------------AMNEI----FLVLVSYVIL 563
            |    ||..:.| |:|.:.:.|                        |.||:    .|.|...::|
 Worm   282 LDFENICNFINAVFVLQVKTSPLKKKHMDAMSQEELKQEMETLDEDATNELTQGHHLKLKGQMML 346

  Fly   564 GTFLAIEVAVSYAMQPSKSFNGSACCIVLIYMTYTMLPLRLREALIGGILLSVVHLYTCLRLNAM 628
               ||.:..:.|...|              |:|      .:.|.:..|:.|:.:.|:     :|.
 Worm   347 ---LASKKHIIYLCSP--------------YVT------SINELMQYGMRLTAMPLH-----DAT 383

  Fly   629 QDEAVEMIHWEELLCTLVALLLANLTGVYTHWPKEKAQRKAFIETRQCIEA---RLRT-----QR 685
            :|                 |:|.|            .||.:.:|....:||   :|.|     :.
 Worm   384 RD-----------------LILLN------------QQRLSDVEVNLQLEANNEQLETMTRELEL 419

  Fly   686 ENQQQERLLLSVLPRHVAMEMKDDIAGQPRDTQFHKIYIQRHENVSILFADICGFTSLSDQCTAE 750
            |.|:.:.:|..:|||.:|.::   ::|:       .|....|| .:::|.|:..|.....||:.:
 Worm   420 ERQKTDSILKDMLPRRIAQQL---LSGE-------HIEACEHE-ATVMFCDLPAFQQAIPQCSPK 473

  Fly   751 ELVRLLNELFARFDRLAAEHHCLRIKLLGDCYYCVSGLPEPRPDHAH--CAVEMGLDMIDAIALV 813
            ::|.:|||:|.:.||:.......:::.:.|.|..|||:|:..|:||.  |.|.:|: |.:|.:::
 Worm   474 DIVNMLNEIFRKLDRIVVIRGVYKVETVSDSYMAVSGIPDYTPEHAENMCHVALGM-MWEARSVI 537

  Fly   814 REVMAVNVNMRVGIHTGRVHCGVLGLVKWQFDVWSNDVTLANHMESGGIPGRVHITK 870
            ..|......:|:|||:|.:..||:|.|..::.::...||||:.|||.|:.|::..:|
 Worm   538 DPVSKTPFLLRIGIHSGTITAGVVGTVHPKYCLFGETVTLASQMESLGMAGKIQCSK 594

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43373	NP_001097622.2	AC_N	<523..720	CDD:292831	46/242 (19%)
		CYCc	686..881	CDD:214485	57/187 (30%)
		Guanylate_cyc	722..895	CDD:278633	49/151 (32%)
		DUF1053	<949..1005	CDD:283888
		CYCc	1259..1455	CDD:214485
		Guanylate_cyc	1285..1479	CDD:278633
gcy-32	NP_506452.5	HNOB	3..167	CDD:285002	2/6 (33%)
		HNOBA	226..440	CDD:285003	53/270 (20%)
		CYCc	419..608	CDD:214485	57/188 (30%)
		Guanylate_cyc	452..627	CDD:278633	47/145 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810