| Sequence 1: | NP_001097622.2 | Gene: | CG43373 / 39835 | FlyBaseID: | FBgn0263131 | Length: | 1854 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_066939.1 | Gene: | ADCY1 / 107 | HGNCID: | 232 | Length: | 1119 | Species: | Homo sapiens |
| Alignment Length: | 1018 | Identity: | 415/1018 - (40%) |
|---|---|---|---|
| Similarity: | 585/1018 - (57%) | Gaps: | 133/1018 - (13%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 517 LMQVDESVLVFLIVMLICGIVYAFLLC--ILSKPAMNEIFLVLVSYVILGTFLAIEVAVSYAMQP 579
Fly 580 SKSFNGSACCIVLIYMTYTMLPLRLREALIGGILLSVVHLYTCLRLNAMQDEAVEMIHWEELLCT 644
Fly 645 LVALLLANLTGVYTHWPKEKAQRKAFIETRQCIEARLRTQRENQQQERLLLSVLPRHVAMEMKDD 709
Fly 710 IAGQPRDTQFHKIYIQRHENVSILFADICGFTSLSDQCTAEELVRLLNELFARFDRLAAEHHCLR 774
Fly 775 IKLLGDCYYCVSGLPEPRPDHAHCAVEMGLDMIDAIALVREVMAVNVNMRVGIHTGRVHCGVLGL 839
Fly 840 VKWQFDVWSNDVTLANHMESGGIPGRVHITKETLKCLDGDYEVEVGKGNERNSYLKDHQIETYLI 904
Fly 905 VP------------GDIYRPHKKSRNR---------LQVNGNISKELRMMGHGTAQKHTSKFGFG 948
Fly 949 DSSESAKD------------PEDEVNEYLMRAIDARSIDHLRAEHCQSLLLCFKDNVLERKYASE 1001
Fly 1002 PDRMLCVYFYCSLLVLLGTSIMRLVVFQSSLLTLALSTGALLLLGFLVFLVACHKINFQLPSDIK 1066
Fly 1067 RFSLRIHSNRRISQLFAFASVALIVLTTLLAMF-------QESGRQMELLQRRRFWL---DVNGS 1121
Fly 1122 ISL-----NDTELNTKMYDAEEPDCDFYLAYNTFLLLTLLSMMSCATYQVLRILLKLLLLLLASG 1181
Fly 1182 SY-MACSSNLYSRSREMSQELANEEALLRYIIDSIFLFAFMLALIFHSHQTEATYRLDFIWKLQA 1245
Fly 1246 TEEKEDMEHLQAYNRKLLENILPVHVAEHFLSREKHLDDLYHEQCDSVCILFASIPNFSEFYVEL 1310
Fly 1311 EGNNEGVECLRLLNEIIADFDELLSEERFRCIEKIKSTGATYMAASGL--TANTCDRVNF-SHVT 1372
Fly 1373 AMADYALQLFDKIEEVNMHSFNNFRMRIGINIGPVVAGVIGACKPQYDIWGNAVNVASRMDSTGL 1437
Fly 1438 VDHIQVTQEMQQILEGRGFELTCRGSVDVKGKGSMITYFLKGR 1480 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| CG43373 | NP_001097622.2 | AC_N | <523..720 | CDD:292831 | 57/198 (29%) |
| CYCc | 686..881 | CDD:214485 | 140/194 (72%) | ||
| Guanylate_cyc | 722..895 | CDD:278633 | 128/172 (74%) | ||
| DUF1053 | <949..1005 | CDD:283888 | 16/67 (24%) | ||
| CYCc | 1259..1455 | CDD:214485 | 114/198 (58%) | ||
| Guanylate_cyc | 1285..1479 | CDD:278633 | 115/196 (59%) | ||
| ADCY1 | NP_066939.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..28 | ||
| AC_N | <161..292 | CDD:292831 | 47/135 (35%) | ||
| CYCc | 258..453 | CDD:214485 | 140/195 (72%) | ||
| Guanylate_cyc | 294..476 | CDD:278633 | 134/181 (74%) | ||
| Interaction with calmodulin. /evidence=ECO:0000250 | 493..520 | 3/27 (11%) | |||
| CYCc | 826..1037 | CDD:214485 | 116/210 (55%) | ||
| Guanylate_cyc | 859..1056 | CDD:278633 | 115/196 (59%) | ||
| Interaction with calmodulin. /evidence=ECO:0000250 | 1024..1047 | 8/22 (36%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG2114 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D46761at33208 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 1 | 0.900 | - | - | OOG6_100296 | |
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.720 | |||||