Protein Alignment CG43373 and LOC101884360

DIOPT Version :10

• Sequence 1: NP_001097622.2
• Gene: CG43373 / 39835
• FlyBaseID: FBgn0263131
• Length: 1854
• Species: Drosophila melanogaster
• Sequence 2: XP_073800254.1
• Gene: LOC101884360 / 101884360
• -ID: -
• Length: 1401
• Species: Danio rerio
• Alignment Length: 1339
• Identity: 386/1339 - (28%)
• Similarity: 582/1339 - (43%)
• Gaps: 328/1339 - (24%)

  Fly   531 MLICGIVYAFLLCILSKPAMNEIFLVLVSYVILGTFLAIEVAVS----YAMQPSK----SFNG-- 585
            :|:|.:::.|..........|:..|:|: .|.....||.::..|    :...|.|    .|:|
Zfish   157 LLLCCVLFVFTFTRFYVHCYNQASLLLI-VVTFALTLAPQIQTSGFSDFNAPPLKDEDDDFSGAE 220

  Fly   586 ---------------SACC---------IVLIYMTYTMLPLRLREALIGGILLSV-------VHL 619
                           :.|.         :.::.:.|:.|.:|...:|:.|::.||       :||
Zfish   221 DKNLTFEATQSGDLVTPCLSPVGTFSLGMEVLSLLYSFLHVRFYASLLLGLIYSVLFETLGWMHL 285

  Fly   620 YTCLRLNAMQDEAVEMIHWEELLCTLVALL--LANLTGVYTHWPKEKAQRKAFIETRQCIEARLR 682
            ....|.:...:|.:|.::|   |....|:|  .|::.|::.....|...|..|::..|.|.....
Zfish   286 IQDNRWSNSTEEHLETLYW---LIPGRAILHVCAHIIGIHLFIMSEVRSRSTFLKVGQAIMHGKD 347

  Fly   683 TQRENQQQERLLLSVLPRHVA---MEMKDD--------------IAG--QPRDTQ---------- 718
            .:.|...:||::.||:||.||   |:..||              |||  .|:..:
Zfish   348 LEVEKALKERMIHSVMPRRVADELMKQGDDDNDNSVKRYSTGAAIAGASSPKSAKRKKTSIPRGQ 412

  Fly   719 --FHKIYIQRHENVSILFADICGFTSLSDQCTAEELVRLLNELFARFDRLAAEHHCLRIKLLGDC 781
              |....::|.|.||||||||.|||.:|...:|..||.|||:||.|||||.....|.:|..||||
Zfish   413 IIFRPFNMKRMEPVSILFADIVGFTKMSANKSAHALVGLLNDLFGRFDRLCELTCCEKISTLGDC 477

  Fly   782 YYCVSGLPEPRPDHAHCAVEMGLDMIDAIALVREVMAVNVNMRVGIHTGRVHCGVLGLVKWQFDV 846
            ||||:|.||||.|||:|.|||||.||.||....:.....||||||||||.|.||:||:.:::|||
Zfish   478 YYCVAGCPEPREDHAYCCVEMGLGMIQAIEQFCQEKKEMVNMRVGIHTGTVLCGILGMKRFKFDV 542

  Fly   847 WSNDVTLANHMESGGIPGRVHITKETLKCLDGDYEVEVGKGNER--NSYLKDH--QIETYLIVPG 907
            |||||.|||.||..|:.|:||:::.|.|.||..|..|.|:..||  .|.:.|.  .::||||...
Zfish   543 WSNDVNLANLMEQLGVAGKVHLSEATDKFLDDRYLREDGRVTERIGPSVVADQLKGLKTYLISGR 607

  Fly   908 DI-----YRPHKKSRNRLQV-NGNISKELRMMGHG-------------TAQKHTSKFGFGDSSES 953
            .:     ..|...|..|..| :.:.|.::......             :....||:.|...|: |
Zfish   608 KVKLCQWMSPPPPSEIRASVSSSSFSPDVSASAGAPTDAPDRAKSACPSCSLITSEDGLVHSN-S 671

  Fly   954 AKDPEDE--------------VNEYLMRAIDARSIDHLRAEHCQ--------------------S 984
            ..|||.:              ||..|...:: :.:.|.:...|:                    :
Zfish   672 CTDPEHKTSNSKVPAGRGPKSVNGLLSPGVE-QPLTHSQTSLCEMLQDKEKKWPAVGGGTMDHSA 735

  Fly   985 LLLCFKDNVLERKYAS-----EPDRMLCVYFY-------------CSLLVLLGTSIMRLVVFQSS 1031
            |:.....|..||..|.     :.|.::..|||             .||.....||....|..|:.
Zfish   736 LIPLRSKNFRERSDAHFVDVIKEDSLMKDYFYRPPINKLSHTFIDRSLESAYRTSYQDEVKTQTP 800

  Fly  1032 LLTLALSTGAL---LLLGFLVFL---VACHKINFQLPSDIKRFSLRIHSNRRISQLFAFASVALI 1090
            :.|.|..|.:.   :||...|||   :||    |..|       |..|.......|...|..||:
Zfish   801 VQTFASPTFSSFLDMLLCCCVFLALSLAC----FLRP-------LVTHQPLPTPALIVAAVAALL 854

  Fly  1091 -VLTTLLAMFQESGRQMELLQRRRFWLD------------VNGSISLN--------------DTE 1128
             .|..:||:            ||.|:||            ::|.|..:              .:.
Zfish   855 ECLALILAI------------RRAFYLDSVLNCTRTLLWVISGWIPRHMIGAVLVSLPAIAVFSH 907

  Fly  1129 LNTKMYDAEEPDCDFYLAYNTFLLLT----LLSMMSCATYQVLRILLKLLLLLLASGSYMA---- 1185
            :...|:|:.:           |.:.|    :::::....:..|...::..|..||..::::
Zfish   908 ITCNMHDSIQ-----------FTMFTCCAVIIAIIQYCNFCQLSFWMRSSLATLAGLTFLSVLWS 961

  Fly  1186 --CSS--NLYSRSREMS------QELANEEALLRYIIDSIFLFAFMLALI---FHSHQTEATYRL 1237
              ||:  .|:.||.:::      |..|.|.:.|:.::....|.||.|.|:   |.:.:.|.:|||
Zfish   962 PPCSTWEQLFLRSNDLNSSINDIQSSAEEPSRLQDLLGPEALVAFFLLLLLVWFLNREFEVSYRL 1026

  Fly  1238 DFIWKLQATEEKEDMEHLQAYNRKLLENILPVHVAEHFLSREKHLDDLYHEQCDSVCILFASIPN 1302
            .:...::|.:.:..:::::.....||.||:|:||||     :..:...|.:..|:|.::||||.|
Zfish  1027 HYHGNVEADQHRIKIQNMRDQADWLLRNIIPIHVAE-----QLKVTQSYSKNHDNVGVIFASIVN 1086

  Fly  1303 FSEFYVE-LEGNNEGVECLRLLNEIIADFDELLSEERFRCIEKIKSTGATYMAASGLTANTCDRV 1366
            |||||.| .||   |.||.|:|||:|.||||||.:..|..|||||:.||||||||||....|...
Zfish  1087 FSEFYEESYEG---GKECYRVLNELIGDFDELLRKSDFSNIEKIKTIGATYMAASGLNTQQCSDQ 1148

  Fly  1367 N--FSHVTAMADYALQLFDKIEEVNMHSFN-NFRMRIGINIGPVVAGVIGACKPQYDIWGNAVNV 1428
            |  .:|:.|:.:::|::...:::.|.:... .|::|||.|.||:.|||||..|..|||||:.||:
Zfish  1149 NHPHAHLRALFEFSLEMMRVVDDFNKNMLGFKFKLRIGFNHGPLTAGVIGTTKLLYDIWGDTVNI 1213

  Fly  1429 ASRMDSTGLVDHIQVTQEMQQILEGRGFELTCRGSVDVKGKGSMITYFLKGRRPIDAKELELAKT 1493
            |||||:||:...:||::|...:|.|..:|...||:|:|||||.|.||..
Zfish  1214 ASRMDTTGVECRVQVSEESYCVLSGMDYEFDYRGTVNVKGKGQMKTYLY---------------- 1262

  Fly  1494 EVEPPKTLTLAKEPEKLDSGTATEKQ-------REQVKEQGSTEQEDDLLPSPDIDMNSNMQNLT 1551
                         |:..|||...:.|       |.||  .||..:.    |:.:|   :||...|
Zfish  1263 -------------PKSADSGPVPQYQLSVSPEIRAQV--DGSIGRS----PTDEI---ANMVPTT 1305

  Fly  1552 AQRR--------KSLCRQHNISSSFGTTVSSSTGITPSISNSSSVVTIGALPAILRGGNPLSNAN 1608
            :..|        ..|..|......|...|:.|.| |.....|:|.|.:..:|.        :|.:
Zfish  1306 SASRVGASFSVSSGLTGQGYAGRDFPEKVAVSNG-TSKTQRSASAVGLTCIPE--------TNLS 1361

  Fly  1609 PNATDSCSECGGASKSLATPTAPPRTLVADLKDEIARDE 1647
            .:.|           |...|..|..|....:::.|.|.:
Zfish  1362 ASTT-----------SFDKPADPTLTSPIWVENTIGRKQ 1389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43373	NP_001097622.2	AC_N	<523..720	CDD:318454	54/262 (21%)
		Guanylate_cyc	722..904	CDD:425528	100/185 (54%)
		Adcy_cons_dom	<949..1005	CDD:461877	16/94 (17%)
		Guanylate_cyc	1285..1479	CDD:425528	96/197 (49%)
LOC101884360	XP_073800254.1	None