Protein Alignment CG43373 and gucy1b1

DIOPT Version :9

• Sequence 1: NP_001097622.2
• Gene: CG43373 / 39835
• FlyBaseID: FBgn0263131
• Length: 1854
• Species: Drosophila melanogaster
• Sequence 2: NP_001238874.1
• Gene: gucy1b1 / 100150304
• ZFINID: ZDB-GENE-090313-160
• Length: 608
• Species: Danio rerio
• Alignment Length: 539
• Identity: 133/539 - (24%)
• Similarity: 220/539 - (40%)
• Gaps: 162/539 - (30%)

  Fly   416 EKRSLQD--AGLVK-------GGGIQTQLIVDTATDDDADVYTVASDDD------DDVDGGRSAG 465
            |:..|||  .|::|       |..|:.::|...:.:.|...:.:...|.      :|:||....|
Zfish   138 EREGLQDIVIGIIKTVAQQIHGTEIEMKVIQPKSEECDHIKFLIEEKDSEEEAFYEDLDGFEENG 202

  Fly   466 SKHITYTPRVRDYNQISHAERDEVLNTSSNAGVATDNSDPPLGYGQLIPLILMQVDESVLVFLIV 530
            ::.          .:||                       |..:.:..|..|| .|:.     ::
Zfish   203 TQE----------TRIS-----------------------PYTFCKAFPFHLM-FDKD-----LM 228

  Fly   531 MLICGIVYAFLLCILSKPAMNEIFLVLVSYV-----ILGTFLAIEVAVSYAMQPSKSFNGSACCI 590
            :..||               |.||.||....     :...|..:...:.:      ||:|
Zfish   229 LTQCG---------------NAIFRVLPQLQPGVCNLSSVFSLVRPHIDF------SFHG----- 267

  Fly   591 VLIYMTYTMLPLRLREALIG-----------GILLSVVHLYTCLRLNAMQDEAVEMIHWEE---- 640
            :|.::. |:..||.:|.|:.           |..:|      ||||..      :||...|
Zfish   268 ILSHIN-TVFVLRSKEGLLNVETAENEDELTGTEIS------CLRLKG------QMISLPETENI 319

  Fly   641 -LLCTLVALLLANLT--GVY-THWPKEKAQRKAFI-------ETRQCIEARLRTQR--------- 685
             .||:...:.|.:||  |:| :..|...|.|...:       |.:...|..:.|.|
Zfish   320 LFLCSPSVMNLDDLTRRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQHTLRALE 384

  Fly   686 -ENQQQERLLLSVLPRHVAMEMKDDIAGQPRDTQFHK--IYIQRHENVSILFADICGFTSL-SDQ 746
             |.::.:|||.||||..||.|::            ||  :..:|::||:|||:.|.||.:. |..
Zfish   385 DEKKKTDRLLYSVLPPSVANELR------------HKRPVPAKRYDNVTILFSGIVGFNAFCSKH 437

  Fly   747 CTAE---ELVRLLNELFARFDRLAAEH---HCLRIKLLGDCYYCVSGLPEPRPDHAHCAVEMGLD 805
            .:||   ::|.|||:::.|||.|....   :..:::.:||.|..|||||||...||.....:.||
Zfish   438 ASAEGAIKIVNLLNDIYTRFDILTDSRKNPYVYKVETVGDKYMTVSGLPEPCTHHAKSICHLALD 502

  Fly   806 MIDAIALVREVMAVNVNMRVGIHTGRVHCGVLGLVKWQFDVWSNDVTLANHMESGGIPGRVHITK 870
            |::....|: |....|.:.:|||||.|..||:|....::.::.|.|.|.:..|:.|..|::::::
Zfish   503 MMEIAGQVK-VDEDPVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSE 566

  Fly   871 ETLKCL------DGDYEVE 883
            .|.:||      |..:.:|
Zfish   567 YTYRCLQSVENADPQFHLE 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43373	NP_001097622.2	AC_N	<523..720	CDD:292831	51/237 (22%)
		CYCc	686..881	CDD:214485	70/209 (33%)
		Guanylate_cyc	722..895	CDD:278633	58/175 (33%)
		DUF1053	<949..1005	CDD:283888
		CYCc	1259..1455	CDD:214485
		Guanylate_cyc	1285..1479	CDD:278633
gucy1b1	NP_001238874.1	HNOB	2..166	CDD:285002	8/27 (30%)
		HNOBA	207..406	CDD:285003	57/266 (21%)
		CYCc	385..584	CDD:214485	70/211 (33%)
		Guanylate_cyc	412..605	CDD:278633	58/175 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810