Protein Alignment CG43373 and adcy7

DIOPT Version :9

• Sequence 1: NP_001097622.2
• Gene: CG43373 / 39835
• FlyBaseID: FBgn0263131
• Length: 1854
• Species: Drosophila melanogaster
• Sequence 2: NP_001106549.1
• Gene: adcy7 / 100127741
• XenbaseID: XB-GENE-1005225
• Length: 1061
• Species: Xenopus tropicalis
• Alignment Length: 1041
• Identity: 377/1041 - (36%)
• Similarity: 570/1041 - (54%)
• Gaps: 144/1041 - (13%)

  Fly   525 LVFLIVMLICGIVYAFLLCILSKPAMNEIFLVLVSYVILGTFLAIEVAVSYAMQPSKSFNGSACC 589
            |.|:|.:.:..:|:..|..::...:..:.:|.:.|.||....|.|...::|......:::.....
 Frog    64 LAFIITVFVALVVFCALYILVYTESFVQKWLRVFSLVIYICLLTIGYVLTYDSSVVHAWDQVPFF 128

  Fly   590 IVLIYMTYTMLPLRLREALIGGILLSVVHLYT---CLRLNAMQDEAVEMIHWEELLCTLVALLLA 651
            :.:.:..||||||.::..||..|:..:.|:..   .:.|::..::|:..    :|:...|..|..
 Frog   129 LFITFSVYTMLPLGMQACLIVSIISGISHIIVISITVVLSSGSNDAIAF----QLMANAVIFLCG 189

  Fly   652 NLTGVYTHWPKEKAQRKAFIETRQCIEARLRTQRENQQQERLLLSVLPRHVAMEMKDDIAGQPR- 715
            ||.|.|..:..:.|.|..:..|.:||..:::.:.:.:|||.|||||||.:::||||  :|.|.|
 Frog   190 NLMGAYHKYHMQDASRDLYSYTVKCIRIKMKLELKKRQQESLLLSVLPVYISMEMK--LAIQDRL 252

  Fly   716 ---------DTQFHKIYIQRHENVSILFADICGFTSLSDQCTAEELVRLLNELFARFDRLAAEHH 771
                     |..||.:|::||:|||||:|||.|||.|:..|:.:|||.:|||||.:||::|.|:.
 Frog   253 TETNDNRQPDNNFHSLYVKRHQNVSILYADIVGFTRLASDCSPKELVVMLNELFGKFDQIAKENE 317

  Fly   772 CLRIKLLGDCYYCVSGLPEPRPDHAHCAVEMGLDMIDAIALVREVMAVNVNMRVGIHTGRVHCGV 836
            |:|||:||||||||||||...|::|...|:||||:.:||..|||....::|||||:|:|.|.|||
 Frog   318 CMRIKILGDCYYCVSGLPVSLPNNAKNCVKMGLDICEAIKQVREATGADINMRVGVHSGNVLCGV 382

  Fly   837 LGLVKWQFDVWSNDVTLANHMESGGIPGRVHITKETLKCLDGDYEVEVGKGNERNSYLKDHQIET 901
            :||.||||||||:||:|||.|||.|:|||||||:.|||.::|.|:||.|.|..|:.|||:..|:|
 Frog   383 IGLRKWQFDVWSHDVSLANRMESAGLPGRVHITEATLKHMNGAYDVEEGHGELRDPYLKEMNIKT 447

  Fly   902 YLIV--------------------PGDIYRPHKKSRNRLQ-----------------------VN 923
            :|::                    .|...||..:....|:                       ||
 Frog   448 FLVIDPRAKNSRVKNNHLTRHRVNDGIKVRPSVRMTRYLESWGAARPFSHFDQTDASSTEVPTVN 512

  Fly   924 GNISKELRMMGHGTAQKHTSKFGFGDSSESAKDPEDEVNEYLMRAIDARSIDHL---RAEHCQSL 985
            |....|:.:.|.|...| |.:     :....::.|:|:::.:|..||..|....   :.:.....
 Frog   513 GKPKPEIPLKGMGRTVK-TER-----NVSQKRNQEEELHDRMMNTIDGLSSAKPWFGKTDDFYGF 571

  Fly   986 LLCFKDNVLERKYASEPDRMLCV--YFYCSLLVLLGTSIMRLVVFQSSLLTLALSTGALLLLGFL 1048
            ||.|..:.||::|.:  .|:.|:  ||.|:.|:.|...:::::|...| ..|.:|.|.:.:|...
 Frog   572 LLFFTADGLEKEYRT--FRIPCIQSYFLCASLIFLCIFLIQILVMPRS-ANLGISFGVVSVLILW 633

  Fly  1049 VFLVA----CHKI-NFQLPSDIKRF------------SLRIHSNRRISQLFAFASVALIVLTTLL 1096
            |.|:.    |.:. |...|  ..||            |||:       .|.|....:|::::.:
 Frog   634 VLLICYVDKCARFCNENAP--FSRFLCSLVEMIETRPSLRV-------PLVALTLGSLLIISIV- 688

  Fly  1097 AMFQESGRQMELLQRRRFWLDVNGSISLNDT--ELNTKMYDAEEPDCDFYLAYNTFLLLTLLSMM 1159
                                    ::.|:.|  ..||... |.|..|. .:.|  ::...:|.::
 Frog   689 ------------------------NLPLDQTLQTCNTSSI-ATESQCQ-SIPY--YVYCCILGLV 725

  Fly  1160 SCATYQVLRILLKLLLLLLASGSYMACSSNLYS---RSREMSQELANEEALLRYIIDSIFLFAFM 1221
            :|:.:..:...||:|||..|..:|.....:.:|   || .::..:...|...:  :...:|..:.
 Frog   726 ACSMFLRMCFELKILLLTAAFTAYNVIIFHTHSSIFRS-NLNSSIGVLEDFQK--MSCFYLSLYY 787

  Fly  1222 LALIFHSHQTEATYRLDFIWKLQATEEKEDMEHLQAYNRKLLENILPVHVAEHFLSREKHLDDLY 1286
            |.|:..:.|.|...|||.:||.:..:|.|::|.::..|:.||||:||.|||.:|:...:..:|||
 Frog   788 LTLVLLARQVEYYSRLDCLWKRKFRKEDEEIETMENLNQLLLENVLPAHVAAYFIDDNRSNEDLY 852

  Fly  1287 HEQCDSVCILFASIPNFSEFYVELEGNNEGVECLRLLNEIIADFDELLSEERFRCIEKIKSTGAT 1351
            |:..|.||::|||:|.|..||.|.:.|.||:|||||||||||||||||.:.:|..:||||:.|:|
 Frog   853 HQSYDCVCVMFASVPEFKVFYTECDVNKEGLECLRLLNEIIADFDELLMKPKFSGVEKIKTIGST 917

  Fly  1352 YMAASGLTA-----NTCDRVNFSHVTAMADYALQLFDKIEEVNMHSFNNFRMRIGINIGPVVAGV 1411
            ||||:||||     |.......:.:....:||:.|..|::.:|.|||||||:|:|||.|||:|||
 Frog   918 YMAATGLTATPGQENQDQEKQHALIGITVEYAMALMSKLDGINRHSFNNFRLRVGINHGPVIAGV 982

  Fly  1412 IGACKPQYDIWGNAVNVASRMDSTGLVDHIQVTQEMQQILEGRGFELTCRGSVDVKGKGSMITYF 1476
            |||.|||||||||.|||||||:|||.:..||||:|..|||||.|:...|||.::|||||.:.|||
 Frog   983 IGAKKPQYDIWGNTVNVASRMESTGELGKIQVTEETCQILEGLGYSCECRGFINVKGKGELRTYF 1047

  Fly  1477 L 1477
            :
 Frog  1048 V 1048

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG43373	NP_001097622.2	AC_N	<523..720	CDD:292831	54/207 (26%)
		CYCc	686..881	CDD:214485	117/204 (57%)
		Guanylate_cyc	722..895	CDD:278633	104/172 (60%)
		DUF1053	<949..1005	CDD:283888	12/58 (21%)
		CYCc	1259..1455	CDD:214485	116/200 (58%)
		Guanylate_cyc	1285..1479	CDD:278633	116/198 (59%)
adcy7	NP_001106549.1	AC_N	<21..266	CDD:318454	54/207 (26%)
		Guanylate_cyc	268..418	CDD:306677	93/149 (62%)
		DUF1053	483..591	CDD:399378	22/115 (19%)
		Guanylate_cyc	851..1048	CDD:306677	115/196 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45627
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010