Protein Alignment CG33158 and RIA1

DIOPT Version :10

• Sequence 1: NP_788515.1
• Gene: CG33158 / 39834
• FlyBaseID: FBgn0053158
• Length: 1033
• Species: Drosophila melanogaster
• Sequence 2: NP_014236.1
• Gene: RIA1 / 855558
• SGDID: S000005107
• Length: 1110
• Species: Saccharomyces cerevisiae
• Alignment Length: 1173
• Identity: 431/1173 - (36%)
• Similarity: 632/1173 - (53%)
• Gaps: 204/1173 - (17%)

  Fly     1 MPVVEGSDLVLLQRRRQQVRNICILAHVDHGKTTLADSLVASNGIISQRMAGKLRYLDNRSDEQE 65
            ||.||......||.....:|||||:||||||||:|:|||:|||||||||:|||:|:||.|.|||.
Yeast     1 MPRVESETYKRLQNDPSCIRNICIVAHVDHGKTSLSDSLLASNGIISQRLAGKIRFLDARPDEQL 65

  Fly    66 RGITMKSSSISLYYQEAEEMAGN-----PDYLINLIDSPGHVDFSSEVSTAVRLCDGAIVVVDVV 125
            |||||:||:||||::...:..|:     .::|:||||||||:|||||||.|.||||||:|:||||
Yeast    66 RGITMESSAISLYFRVLRKQEGSDEPLVSEHLVNLIDSPGHIDFSSEVSAASRLCDGAVVLVDVV 130

  Fly   126 EGVGPQTRACLRQIYEEQLKPVLVLNKLDRLILEKQMDPLDAYFHLCQVLEQVNAVLGSIFAS-- 188
            |||..||...|||.:.|:|||:|||||:||||.|.|:.|.:||.||.:|:||||:|:||.||:
Yeast   131 EGVCSQTVTVLRQCWTEKLKPILVLNKIDRLITELQLTPQEAYIHLSKVIEQVNSVIGSFFANER 195

  Fly   189 ---DILAKEDITKKDNYESALEEVDDSELYFSPSSGNVIFCSAYDGWAFSVRDFAAMYAKRLEMS 250
               |:..:|.:.|.:|.|..  |.|||.:||:|:..||||.||.|||.|::...|..|.::|...
Yeast   196 QLDDLFWREQLEKNENAEYI--EKDDSGIYFNPTDNNVIFASAIDGWGFNIGQLAKFYEQKLGAK 258

  Fly   251 RKDLENVLWGDFYYNSKKKEAL--PGAQEKAKKPMFVQFVLENIWSLYDIIAIRKDKDKLPGIAE 313
            |::|:.|||||||.:.|.|:.:  .|.:.::.||:|...:|||||.:|..|...:|.:.:..||:
Yeast   259 RENLQKVLWGDFYMDPKTKKIINNKGLKGRSLKPLFTSLILENIWKIYQNIITSRDSEMVEKIAK 323

  Fly   314 KLGLKLATRDLRLTDPKLQIKAVLGQWLPIDKSVLHMVIQHVPPPHKISDERAQRLLYPANVDLS 378
            .|.:||..||||..|.|..::.::|||||:..:||..||:.:|.|.:...:|...:|. :..|.:
Yeast   324 TLNIKLLARDLRSKDDKQLLRTIMGQWLPVSTAVLLTVIEKLPSPLESQTDRLNTILV-SESDTA 387

  Fly   379 SLPPETLELKESFTSCDANSSNVIAFVSKMTPVHITHLPQNRPKRLTDQEVQQRRDEVRRRIEER 443
            ::.|..|   ::..:|| ....|.|:||||..:....||....:..:..|:.:|..:.|   ||.
Yeast   388 AMDPRLL---KAMKTCD-KEGPVSAYVSKMLSIPREELPVESKRIASSDELMERSRKAR---EEA 445

  Fly   444 KQQSEQA---------ELEKISQGVEQL----STQVVGPE-KEESKPEEA--------------- 479
            ...::.|         :|...|:....|    ...|:.|| .|::||:.:
Yeast   446 LNAAKHAGMVENMAMMDLNDNSKNTSDLYKRAKDTVMTPEVGEQTKPKPSRNNDVFCVVSEPSSA 510

  Fly   480 ----------------------------------------------------------------- 479
                                                                             
Yeast   511 LDLEFEYEGEDDSDSQDNFGLDFVPTDIDPNDPLSSMFEYEEEDPLLESIKQISEDVNDEVDDIF 575

  Fly   480 DQNEFVFIAFARVFSGTLKRGMELFNLSPKHDPRQPTHRKEGEAPYASRVTIGDLYMFMGGELQL 544
            |:.|...:||||::||||:.|.|:..|.||:||:.|....|       ...|..||:|||.||..
Yeast   576 DEKEECLVAFARIYSGTLRVGQEISVLGPKYDPKCPEEHIE-------TAIITHLYLFMGKELVP 633

  Fly   545 LDEVPAGNIVGIGGLESHIVKTATL-SSSLDCTSFSELSVMATPILRVAIEPVQPQDMPKLVKGL 608
            ||..|:||||||.||...::|:.|| ...:...:.:.::...|||:|||:||..|.:|.|||:||
Yeast   634 LDVCPSGNIVGIRGLAGKVLKSGTLIEKGVQGVNLAGVNFHFTPIVRVAVEPANPVEMSKLVRGL 698

  Fly   609 KLLNQADACVQVSVAPTGEHVITTLGEVHVEKCVHDLEQSYAKIKVNVSKPIVSFRETIVPAATV 673
            |||:|||.||...|..||||::.|.||:|:|:|:.||.:.:|.|::..|:|.:.:|||.:.|:
Yeast   699 KLLDQADPCVHTYVENTGEHILCTAGELHLERCLKDLTERFAGIEITHSEPAIPYRETFLSAS-- 761

  Fly   674 DMVNEAIVKTAEDKDVSKKIAVQQTLNKLGTLKVIAVPLPAEAVELLETHSEFFKEL-------- 730
            ||      ...::..:.:  .|.:.|.....:.....||..:..:.|..|....|.:
Yeast   762 DM------NPPQNSQLGR--GVHELLLSQYKITFRTFPLSGKVTDFLSQHQNSIKNILKTSTSSM 818

  Fly   731 ---------AAIPRNQLL---------SEKWTALLASIKVKLIAALKDLQLFGLSTLSPEELVNR 777
                     :.:.:..||         .||...||:..||||.
Yeast   819 DPVIESTGSSFLDKKSLLVAFEEVINQEEKSRELLSGFKVKLA---------------------- 861

  Fly   778 IWALGPRNCGTNILLNLSDYEQPDFWSSHAKSDTDIRSKTDPRKDFNSSLVNGFQITSVAGPLCE 842
              ..||...|.||||:     |.:...|       :...|....:::.|:.||||:....|||..
Yeast   862 --GFGPSRVGCNILLS-----QDNLLGS-------LFEGTPAAFEYSDSIKNGFQLAVSEGPLAN 912

  Fly   843 EPMQGVCFAVLEWSIQSEGEDLNSRGP--------FSGQVLTAAKEVCRQAFQNQPQRLVTPMYS 899
            ||:||:|..|......|:.|..:...|        .||:::|:.::...:||.:...|::..:||
Yeast   913 EPVQGMCVLVESVHKMSQDEIESIEDPRYQQHIVDLSGRLITSTRDAIHEAFLDWSPRIMWAIYS 977

  Fly   900 CNIVVNAEMLGKMYAVIGRRHGKILSGDLTQGSGNFAVTCLLPVIESFNFAQEMRKQTSGLACPQ 964
            |:|..:.::|||:||||.:|||||:|.::.:|:..|.:...:||:|:|..::::||:|||.|.||
Yeast   978 CDIQTSVDVLGKVYAVILQRHGKIISEEMKEGTPFFQIEAHVPVVEAFGLSEDIRKRTSGAAQPQ 1042

  Fly   965 LMFSHWEVIDIDPFWLPTTEEELMHFGEKADSANRAKVYMDSVRRRKGLFVDEQVVEHAEKQRTL 1029
            |:||.:|.||:||||:|||||||...|:.||..|.|:.:|:::|||||||::|:|||:|||||||
Yeast  1043 LVFSGFECIDLDPFWVPTTEEELEELGDTADRENIARKHMNAIRRRKGLFIEEKVVENAEKQRTL 1107

  Fly  1030 SKN 1032
            .||
Yeast  1108 KKN 1110

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33158	NP_788515.1	PRK13351	15..1016	CDD:481252	412/1141 (36%)
RIA1	NP_014236.1	PRK13351	1..1091	CDD:481252	415/1152 (36%)