Protein Alignment CG33158 and MEF1

DIOPT Version :9

• Sequence 1: NP_788515.1
• Gene: CG33158 / 39834
• FlyBaseID: FBgn0053158
• Length: 1033
• Species: Drosophila melanogaster
• Sequence 2: NP_013170.1
• Gene: MEF1 / 850758
• SGDID: S000004059
• Length: 761
• Species: Saccharomyces cerevisiae
• Alignment Length: 1003
• Identity: 202/1003 - (20%)
• Similarity: 341/1003 - (33%)
• Gaps: 346/1003 - (34%)

  Fly    15 RRQQVRNICILAHVDHGKTTLADSLV-------ASNGIISQRMAGKLRYLDNRSDEQERGITMKS 72
            |..::|||.|.||:|.||||..:.::       |.:.:..:...|  ..:|:...|:|:|||::|
Yeast    66 RCNKLRNIGISAHIDSGKTTFTERVLYYTKRIKAIHEVRGRDNVG--AKMDSMDLEREKGITIQS 128

  Fly    73 SSISLYYQEAEEMAGNPDYLINLIDSPGHVDFSSEVSTAVRLCDGAIVVVDVVEGVGPQTRACLR 137
            ::....:.:.     ..:|..||||:|||:||:.||..|:|:.|||::||..|.||..||....|
Yeast   129 AATYCSWDKE-----GKNYHFNLIDTPGHIDFTIEVERALRVLDGAVLVVCAVSGVQSQTVTVDR 188

  Fly   138 QIYEEQLKPVLVLNKLDRLILEKQMDPLDAYFHLCQVLEQVNAVLGSIFASDILAKEDITKKDNY 202
            |:....:..|..:||:||:    ..||..|       :||:|:.| .|.|:.:  :..|..:.:.
Yeast   189 QMRRYNVPRVTFINKMDRM----GSDPFRA-------IEQLNSKL-KIPAAAV--QIPIGSESSL 239

  Fly   203 ESALEEVDDSELYFSPSSGNVIFCSAYDGWAFSVRDFAAMYAKRLEMSRKDLENVLWGDFYYNSK 267
            ...::.::...:|....:|.:|
Yeast   240 SGVVDLINRVAIYNKGDNGEII------------------------------------------- 261

  Fly   268 KKEALPGAQEKAKKPMFVQFVLENIWSLYDIIAIRKDKDKLPGIAEKLGLKLATRDLRLTDPKLQ 332
                     ||...|       ||:               .|.:.||..|.:.|    |.|
Yeast   262 ---------EKGPVP-------ENL---------------KPLMEEKRQLLIET----LAD---- 287

  Fly   333 IKAVLGQWLPIDKSVLHMVIQHVPPPHKISDERAQRLLYPANVDLSSLPPETLELKE-------- 389
                                        :.||.|:..       |....|.|.::|:
Yeast   288 ----------------------------VDDEMAEMF-------LEEKEPTTQQIKDAIRRSTIA 317

  Fly   390 -SFTSCDANSSNVIAFVSKMTPVHITHLPQNRPKRLTDQEVQQRRDEVRRRIEERKQQSEQAELE 453
             |||.....|:.....:..:....:.:||  .|..:.:..:....:|.:..:....||.......
Yeast   318 RSFTPVLMGSALANTGIQPVLDAIVDYLP--NPSEVLNTALDVSNNEAKVNLVPAVQQPFVGLAF 380

  Fly   454 KISQGVEQLSTQVVGPEKEESKPEEADQNEFVFIAFARVFSGTLKRGMELFNLSPKHDPRQPTHR 518
            |:.:|                        ::..:.:.||:.|.|::|..:.|:
Yeast   381 KLEEG------------------------KYGQLTYVRVYQGRLRKGNYITNV------------ 409

  Fly   519 KEGEAPYASRVTIGDLYMFMGGELQLLDEVPAGNIVGIGGLESHIVKTATLSSSLDCTS---FSE 580
            |.|:     :|.:..|......|::.:|||.:|.|....|              :||.|   |::
Yeast   410 KTGK-----KVKVARLVRMHSSEMEDVDEVGSGEICATFG--------------IDCASGDTFTD 455

  Fly   581 ------LSVMATP--ILRVAIEPVQPQDMPKLVKGLKLLNQADACVQVSVAP-TGEHVITTLGEV 636
                  :|.|..|  ::.::|.| ..:|.....|.|....:.|...:|...| :.|.:|:.:||:
Yeast   456 GSVQYSMSSMYVPDAVVSLSITP-NSKDASNFSKALNRFQKEDPTFRVKFDPESKETIISGMGEL 519

  Fly   637 HVEKCVHDLEQSYAKIKVNVSKPIVSFRETIVPAATVDMVNEAIVKTAEDKDVSKKIAVQQTLNK 701
            |:|..|..:.:.| .:.....||.||:||:|...|..|..::           .:.....|....
Yeast   520 HLEIYVERMRREY-NVDCVTGKPQVSYRESITIPADFDYTHK-----------KQSGGAGQYGRV 572

  Fly   702 LGTLKVIAVPLPAEAVELLETHSEFFKELAAIPRNQLLSEKWTALLAS-IKVKLIAALKDLQLFG 765
            :|||.      |.:.:    |....|:               ||::.. |..|.:||...    |
Yeast   573 IGTLS------PVDDI----TKGNIFE---------------TAIVGGRIPDKYLAACGK----G 608

  Fly   766 LSTLSPEELVNRIWALGPRNCGTNILLNLSDYEQPDFWSSHAKSDTDIRSKTDPRKDFNSSLVNG 830
            .     ||:..:...:|.|.....:|:|..        :.||....::..||.....|..:.:.
Yeast   609 F-----EEVCEKGPLIGHRVLDVKMLINDG--------AIHAVDSNELSFKTATMSAFRDAFLR- 659

  Fly   831 FQITSVAGPLCEEPMQGVCFAVLEWSIQSEGEDLNSRGPFSGQVLTAAKEVCRQAFQNQPQRLVT 895
                  |.|:..||:..|       |:.|..|       |.|.|:
Yeast   660 ------AQPVIMEPIMNV-------SVTSPNE-------FQGNVI-------------------- 684

  Fly   896 PMYSCNIVVNAEMLGKMYAVIGRRHGKILSGDLTQGSGNFAVTCLLPVIESFNFAQEMRKQTSGL 960
                       .:|.|:.|||         .|...|...|.:.....:...|.||..:|..|.|.
Yeast   685 -----------GLLNKLQAVI---------QDTENGHDEFTLKAECALSTMFGFATSLRASTQGK 729

  Fly   961 ACPQLMFSHWEVIDIDPFWLPTTEEELM 988
            ....|.|||:...      .|..::||:
Yeast   730 GEFSLEFSHYAPT------APHVQKELI 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33158	NP_788515.1	PTZ00416	15..1016	CDD:240409	202/1003 (20%)
		EF2	20..249	CDD:206672	64/235 (27%)
		EF2_II	485..572	CDD:293913	17/86 (20%)
		EF2_snRNP_III	587..658	CDD:293918	17/73 (23%)
		aeEF2_snRNP_like_IV	658..899	CDD:238839	45/241 (19%)
		eEF2_snRNP_like_C	896..974	CDD:239763	18/77 (23%)
MEF1	NP_013170.1	FusA	68..760	CDD:223556	201/1001 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0480
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810