DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33158 and LOS1

DIOPT Version :9

Sequence 1:	NP_788515.1	Gene:	CG33158 / 39834	FlyBaseID:	FBgn0053158	Length:	1033	Species:	Drosophila melanogaster
Sequence 2:	NP_001321033.1	Gene:	LOS1 / 842058	AraportID:	AT1G56070	Length:	843	Species:	Arabidopsis thaliana

Alignment Length:	1028	Identity:	315/1028 - (30%)
Similarity:	477/1028 - (46%)	Gaps:	244/1028 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 RQQVRNICILAHVDHGKTTLADSLVASNGIISQRMAGKLRYLDNRSDEQERGITMKSSSISLYYQ 80
            :..:||:.::|||||||:||.|||||:.|||:|.:||.:|..|.|:||.|||||:||:.|||||:
plant    16 KHNIRNMSVIAHVDHGKSTLTDSLVAAAGIIAQEVAGDVRMTDTRADEAERGITIKSTGISLYYE 80

  Fly    81 EAEEMA--------GNPDYLINLIDSPGHVDFSSEVSTAVRLCDGAIVVVDVVEGVGPQTRACLR 137
            ..:|..        || :||||||||||||||||||:.|:|:.|||:||||.:|||..||...||
plant    81 MTDESLKSFTGARDGN-EYLINLIDSPGHVDFSSEVTAALRITDGALVVVDCIEGVCVQTETVLR 144

  Fly   138 QIYEEQLKPVLVLNKLDRLILEKQMDPLDAYFHLCQVLEQVNAVLGSIFASDILAKEDITKKDNY 202
            |...|:::|||.:||:||..||.|:|..:||....:|:|..|.::.:                 |
plant   145 QALGERIRPVLTVNKMDRCFLELQVDGEEAYQTFSRVIENANVIMAT-----------------Y 192

  Fly   203 ESALEEVDDSELYFSPSSGNVIFCSAYDGWAFSVRDFAAMYAKRLEMSRKDLENVLWGDFYYN-- 265
            |..|  :.|.::|  |..|.|.|.:...||||::.:||.|||.:..:....:...|||:.:::
plant   193 EDPL--LGDVQVY--PEKGTVAFSAGLHGWAFTLTNFAKMYASKFGVVESKMMERLWGENFFDPA 253

  Fly   266 ----SKKKEALPGAQEKAKKPMFVQFVLENIWSLYDIIA--IRKDKDKLPGIAEKLGLKLATRDL 324
                |.|....|..     |..||||..|.|   ..|||  :...||||..:..|||:.:...:.
plant   254 TRKWSGKNTGSPTC-----KRGFVQFCYEPI---KQIIATCMNDQKDKLWPMLAKLGVSMKNDEK 310

  Fly   325 RLTDPKLQIKAVLGQWLPIDKSVLHMVIQHVPPPHKISDERAQRLLYPANVDLSSLPPETLELKE 389
            .|....| :|.|:..|||...::|.|:|.|:|.||.....|.:. ||...:|        .:...
plant   311 ELMGKPL-MKRVMQTWLPASTALLEMMIFHLPSPHTAQRYRVEN-LYEGPLD--------DQYAN 365

  Fly   390 SFTSCDANSSNVIAFVSKMTPVHITHLPQNRPKRLTDQEVQQRRDEVRRRIEERKQQSEQAELEK 454
            :..:||.|.. ::.:||||.|.
plant   366 AIRNCDPNGP-LMLYVSKMIPA------------------------------------------- 386

  Fly   455 ISQGVEQLSTQVVGPEKEESKPEEADQNEFVFIAFARVFSGTLKRGMELFNLSPKHDPRQPTHRK 519
                                    :|:..  |.||.|||:|.:..||::..:.|.:.|
plant   387 ------------------------SDKGR--FFAFGRVFAGKVSTGMKVRIMGPNYIP------- 418

  Fly   520 EGEAPYASRVTIGDLY--------MFMGGELQLLDEVPAGNIVGIGGLESHIVKTATLSS--SLD 574
             ||..        |||        ::||...:.:::||.||.|.:.||:..|.|.|||::  .:|
plant   419 -GEKK--------DLYTKSVQRTVIWMGKRQETVEDVPCGNTVAMVGLDQFITKNATLTNEKEVD 474

  Fly   575 CTSFSELSVMATPILRVAIEPVQPQDMPKLVKGLKLLNQADACVQVSVAPTGEHVITTLGEVHVE 639
            ......:....:|::|||::.....|:||||:|||.|.::|..|..::..:|||::...||:|:|
plant   475 AHPIRAMKFSVSPVVRVAVQCKVASDLPKLVEGLKRLAKSDPMVVCTMEESGEHIVAGAGELHLE 539

  Fly   640 KCVHDLEQSY-AKIKVNVSKPIVSFRETIVPAATVDMVNEAIVKTAEDKDVSKKIAVQQTLNKLG 703
            .|:.||:..: ...::..|.|:||||||:.                   |.|.:..:.::.||..
plant   540 ICLKDLQDDFMGGAEIIKSDPVVSFRETVC-------------------DRSTRTVMSKSPNKHN 585

  Fly   704 TLKVIAVPLP---AEAVELLETHSEFFKELAAIPRNQLLSEKWTALLASIKVKLIAALKDLQLFG 765
            .|.:.|.|:.   |||::          :....||:.          ..|:.|::|     :.||
plant   586 RLYMEARPMEEGLAEAID----------DGRIGPRDD----------PKIRSKILA-----EEFG 625

  Fly   766 LSTLSPEELVNRIWALGPRNCGTNILLNLSDYEQPDFWSSHAKSDTDIRSKTDPRKDFNSSLVNG 830
            ..    ::|..:|||.||...|.|:::                   |:........:...|:|.|
plant   626 WD----KDLAKKIWAFGPETTGPNMVV-------------------DMCKGVQYLNEIKDSVVAG 667

  Fly   831 FQITSVAGPLCEEPMQGVCFAVLEWSIQSEGEDLNSRGPFSGQVLTAAKEVCRQAFQNQPQRLVT 895
            ||..|..|||.||.|:|:||.|.:..:.|   |...||  .|||:..|:.|...:......||:.
plant   668 FQWASKEGPLAEENMRGICFEVCDVVLHS---DAIHRG--GGQVIPTARRVIYASQITAKPRLLE 727

  Fly   896 PMYSCNIVVNAEMLGKMYAVIGRRHGKILSGDLTQGSGNFAVTCLLPVIESFNFAQEMRKQTSGL 960
            |:|...|......||.:|:|:.::.|.:.......|:..:.:...|||:|||.|:.::|..|||.
plant   728 PVYMVEIQAPEGALGGIYSVLNQKRGHVFEEMQRPGTPLYNIKAYLPVVESFGFSSQLRAATSGQ 792

  Fly   961 ACPQLMFSHWEVIDIDPFWLPTTEEELMHFGEKADSANRAKVYMDSVRRRKGL 1013
            |.||.:|.|||::..||.                :...:|.|.:..:|:||||
plant   793 AFPQCVFDHWEMMSSDPL----------------EPGTQASVLVADIRKRKGL 829

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33158	NP_788515.1	PTZ00416	15..1016	CDD:240409	315/1028 (31%)
		EF2	20..249	CDD:206672	112/236 (47%)
		EF2_II	485..572	CDD:293913	30/96 (31%)
		EF2_snRNP_III	587..658	CDD:293918	25/71 (35%)
		aeEF2_snRNP_like_IV	658..899	CDD:238839	61/243 (25%)
		eEF2_snRNP_like_C	896..974	CDD:239763	27/77 (35%)
LOS1	NP_001321033.1	PLN00116	1..843	CDD:177730	315/1028 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0480
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D140796at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820