DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG33158 and AT3G22980

DIOPT Version :9

Sequence 1:	NP_788515.1	Gene:	CG33158 / 39834	FlyBaseID:	FBgn0053158	Length:	1033	Species:	Drosophila melanogaster
Sequence 2:	NP_001319621.1	Gene:	AT3G22980 / 821872	AraportID:	AT3G22980	Length:	1015	Species:	Arabidopsis thaliana

Alignment Length:	1096	Identity:	413/1096 - (37%)
Similarity:	605/1096 - (55%)	Gaps:	170/1096 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 QQVRNICILAHVDHGKTTLADSLVASN--GIISQRMAGKLRYLDNRSDEQERGITMKSSSISLYY 79
            ::|||||||||||||||||||.|:||:  |::..|:|||||::|...:||.|.||||||||||.|
plant     7 RKVRNICILAHVDHGKTTLADHLIASSGGGVLHPRLAGKLRFMDYLDEEQRRAITMKSSSISLKY 71

  Fly    80 QEAEEMAGNPDYLINLIDSPGHVDFSSEVSTAVRLCDGAIVVVDVVEGVGPQTRACLRQIYEEQL 144
            :         ||.:||||||||:||.||||||.||.|||:|:||.||||..||.|.|||.:.|:|
plant    72 K---------DYSLNLIDSPGHMDFCSEVSTAARLSDGALVLVDAVEGVHIQTHAVLRQAWIEKL 127

  Fly   145 KPVLVLNKLDRLILEKQMDPLDAYFHLCQVLEQVNAVLGSI----FASDILAKEDITKKDNYESA 205
            .|.|||||:||||.|.::.|::||..|.:::.:||.::.:.    :.||:   :.|....:.|.:
plant   128 TPCLVLNKIDRLIFELRLSPMEAYTRLIRIVHEVNGIVSAYKSEKYLSDV---DSILASPSGELS 189

  Fly   206 LEEV----DDSELYFSPSSGNVIFCSAYDGWAFSVRDFAAMYAKRLEMSRKDLENVLWGDFYYNS 266
            .|.:    ||.|:.|.|..|||:|..|.|||.|.:.:||..||.:|..|...|:..|||..||..
plant   190 AESLELLEDDEEVTFQPQKGNVVFVCALDGWGFGIAEFANFYASKLGASATALQKSLWGPRYYIP 254

  Fly   267 K------KKEALPGAQEKAKKPMFVQFVLENIWSLYDIIAIRKDKDK--LPGIAEKLGLKLATRD 323
            |      ||....|::   .||||||||||.:|.:|: .|:....||  |..:.:...|.:..|:
plant   255 KTKMIVGKKNLSAGSK---AKPMFVQFVLEPLWQVYE-AALDPGGDKAVLEKVIKSFNLSIPPRE 315

  Fly   324 LRLTDPKLQIKAVLGQWLPIDKSVLHMVIQHVPPPHKISDERAQRLLYPA-------NVDLSSLP 381
            |:..|||..:::|:.:|||:..:||.|.::|:|.|......|..||: |.       :|| ||:.
plant   316 LQNKDPKNVLQSVMSRWLPLSDAVLSMAVKHLPDPIAAQAYRIPRLV-PERKIIGGDDVD-SSVL 378

  Fly   382 PETLELKESFTSCDANS-SNVIAFVSKMTPVHITHLPQNRPKRLTDQEVQQRRDEVRRRIEERKQ 445
            .|...:::|..:||::| |..:.|||||..:.:..:||:...|
plant   379 AEAELVRKSIEACDSSSDSPCVVFVSKMFAIPMKMIPQDGNHR---------------------- 421

  Fly   446 QSEQAELEKISQGVEQLSTQVVGPEKEESKPEEADQNEFVFIAFARVFSGTLKRGMELFNLSPKH 510
                          |:::    |...::|| .|:|:   .|:||||:|||.|:.|..:|.::..:
plant   422 --------------ERMN----GLNDDDSK-SESDE---CFLAFARIFSGVLRAGQRVFVITALY 464

  Fly   511 DPRQPTHRKEGEAPYASRVTIGDLYMFMGGELQLLDEVPAGNIVGIGGLESHIVKTATLSSSLDC 575
            ||.    :.|....|.....:..||:.||..|..:.||.|||:|.|.||..:|.|:|||||:.:|
plant   465 DPL----KGESSHKYIQEAELHSLYLMMGQGLTPVTEVKAGNVVAIRGLGPYISKSATLSSTRNC 525

  Fly   576 TSFSELSVMATPILRVAIEPVQPQDMPKLVKGLKLLNQADACVQVSVAPTGEHVITTLGEVHVEK 640
            ...:.:....:|.|||||||..|.||..|:|||:|||:||..|:::|:..||||:...||||:|:
plant   526 WPLASMEFQVSPTLRVAIEPSDPADMSALMKGLRLLNRADPFVEITVSARGEHVLAAAGEVHLER 590

  Fly   641 CVHDLEQSYAKIKVNVSKPIVSFRETIVPAATVDMVNEAIVKTAEDKDVSKKIAVQQTLNKLGTL 705
            ||.||::.:||:.:.||.|:||:||||....: :::......:....|..:|    :|.|....:
plant   591 CVKDLKERFAKVNLEVSPPLVSYRETIEGDGS-NLLESLRSLSLNSSDYIEK----RTPNGRCII 650

  Fly   706 KVIAVPLPAEAVELLETHSEFFKELAAIPRN---QLLSEKWTAL------LASIKVKLIAALKDL 761
            :|..:.||....:||:.::|...::.....:   ::|..:..:|      :..:|.:|:.|
plant   651 RVHVMKLPHALTKLLDENTELLGDIIGGKGSHSVKILESQKPSLGENVDPIEELKKQLVEA---- 711

  Fly   762 QLFGLSTLSPEE------------LVNRIWALGPRNCGTNILLNLSDYEQPD------------F 802
               |:|:.|..|            |:.||||||||..|.|||.      .||            .
plant   712 ---GVSSSSETEKDREKCKTEWSKLLKRIWALGPREKGPNILF------APDGKRIAEDGSMLVR 767

  Fly   803 WSSHAK----------------SDTDIRSKTDPRKDFNSSLVNGFQITSVAGPLCEEPMQGVCFA 851
            .|.|..                |:|.:.|:.   ....||:|:|||:.:.:||||:|||.|:.|.
plant   768 GSPHVSQRLGFTEDSTETPAEVSETALYSEA---LTLESSIVSGFQLATASGPLCDEPMWGLAFT 829

  Fly   852 VLEWSIQSEGEDLNSRGP-----FSGQVLTAAKEVCRQAFQNQPQRLVTPMYSCNIVVNAEMLGK 911
            :  .|..:..||:.:..|     |:|||:||.|:.||.|......|:|..||.|.:....|.||.
plant   830 I--ESHLAPAEDVETDKPENFGIFTGQVMTAVKDACRAAVLQTNPRIVEAMYFCELNTAPEYLGP 892

  Fly   912 MYAVIGRRHGKILSGDLTQGSGNFAVTCLLPVIESFNFAQEMRKQTSGLACPQLMFSHWEVIDID 976
            ||||:.||..:||..::.:||..|.|...:||.|||.||.|:||.|||.|...::.||||:::.|
plant   893 MYAVLSRRRARILKEEMQEGSSLFTVHAYVPVSESFGFADELRKGTSGGASALMVLSHWEMLEED 957

  Fly   977 PFWLPTTEEELMHFGEKAD-SANRAKVYMDSVRRRKGLFVDEQVVEHAEKQRTLSK 1031
            ||::|.||||:..||:.|. ..|.|:..:::|||||||.|:|:||::|.|||||::
plant   958 PFFVPKTEEEIEEFGDGASVLPNTARKLINAVRRRKGLHVEEKVVQYATKQRTLAR 1013

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33158	NP_788515.1	PTZ00416	15..1016	CDD:240409	403/1079 (37%)
		EF2	20..249	CDD:206672	122/238 (51%)
		EF2_II	485..572	CDD:293913	35/86 (41%)
		EF2_snRNP_III	587..658	CDD:293918	38/70 (54%)
		aeEF2_snRNP_like_IV	658..899	CDD:238839	78/294 (27%)
		eEF2_snRNP_like_C	896..974	CDD:239763	36/77 (47%)
AT3G22980	NP_001319621.1	FusA	1..998	CDD:357662	403/1079 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	261	1.000	Domainoid score	I477
eggNOG	1	0.900	-	-		E1_COG0480
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11599
Inparanoid	1	1.050	629	1.000	Inparanoid score	I198
OMA	1	1.010	-	-		QHG53952
OrthoDB	1	1.010	-	-		D140796at2759
OrthoFinder	1	1.000	-	-		FOG0004608
OrthoInspector	1	1.000	-	-		oto3669
orthoMCL	1	0.900	-	-		OOG6_102502
Panther	1	1.100	-	-	LDO	PTHR42908
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3227
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840