Protein Alignment CG33158 and efl1

DIOPT Version :9

• Sequence 1: NP_788515.1
• Gene: CG33158 / 39834
• FlyBaseID: FBgn0053158
• Length: 1033
• Species: Drosophila melanogaster
• Sequence 2: XP_697184.5
• Gene: efl1 / 568741
• ZFINID: ZDB-GENE-130103-6
• Length: 1133
• Species: Danio rerio
• Alignment Length: 1131
• Identity: 520/1131 - (45%)
• Similarity: 726/1131 - (64%)
• Gaps: 130/1131 - (11%)

  Fly     9 LVLLQRRRQQVRNICILAHVDHGKTTLADSLVASNGIISQRMAGKLRYLDNRSDEQERGITMKSS 73
            ::.||::...:||:|||||||||||||||.|||||||||.|:||||||||:|.|||.||||||||
Zfish    27 IIALQKKTAHIRNLCILAHVDHGKTTLADCLVASNGIISSRLAGKLRYLDSREDEQIRGITMKSS 91

  Fly    74 SISLYYQEAEEMAGNPDYLINLIDSPGHVDFSSEVSTAVRLCDGAIVVVDVVEGVGPQTRACLRQ 138
            :|||::     ..|..::||||||||||||||||||||||||||||||||.||||.|||:..|||
Zfish    92 AISLHF-----ATGGVEFLINLIDSPGHVDFSSEVSTAVRLCDGAIVVVDAVEGVCPQTQVVLRQ 151

  Fly   139 IYEEQLKPVLVLNKLDRLILEKQMDPLDAYFHLCQVLEQVNAVLGSIFASDILAKEDITKKD--- 200
            .:.|.::||||:||:||||.|.::...:||.||.::|||||||.|::|.|.:|  |:..:||
Zfish   152 AWLENIRPVLVINKIDRLIAELKLTSQEAYVHLQKILEQVNAVTGTLFTSKVL--EERAEKDAGS 214

  Fly   201 --------------NYESALEEVDDSELYFSPSSGNVIFCSAYDGWAFSVRDFAAMYAKRLEMSR 251
                          ::.:.|||.|||:|||||..|||:|.||.|||.||:..||.||::::.:..
Zfish   215 QSSFTENESGDHVYDWSAGLEETDDSDLYFSPDRGNVVFASAIDGWGFSIHQFAEMYSQKMGIRS 279

  Fly   252 KDLENVLWGDFYYNSKKKEALPGAQEKAKKPMFVQFVLENIWSLYDIIAIRKDKDKLPGIAEKLG 316
            ..|...||||||.|:|.|:.:.|||.|.|||:||||:|:||||:||.:..|:||:|:..:...||
Zfish   280 SVLLKTLWGDFYLNAKAKKIMKGAQSKGKKPLFVQFILDNIWSMYDAVVTRRDKEKVEKMMTSLG 344

  Fly   317 LKLATRDLRLTDPKLQIKAVLGQWLPIDKSVLHMVIQHVPPPHKISDERAQRLLYPANVDLSSLP 381
            ||:.:||||.:|||:.:.|:..||||:.::||.||.:.:|.|.:||.||.::|:........|||
Zfish   345 LKVMSRDLRHSDPKVLLSAICSQWLPLSQAVLSMVCEKLPSPAEISAERVEKLMSVGARRFDSLP 409

  Fly   382 PETLELKESFTSCDAN-SSNVIAFVSKMTPVHITHLPQNRPKRLTDQEVQQRRDEVRRRIEERKQ 445
            .:|.|||::|..|.|: ::.||.|||||..|....||||:.:.||.:|:.|||:..|:|..|::.
Zfish   410 DKTQELKKAFLDCSADETAPVIVFVSKMFAVDSKALPQNKQRPLTHEEISQRRELARQRHAEKQA 474

  Fly   446 QSEQAELEKISQG---------------VEQLSTQVVGPEKEESKPEEADQNEFVFIAFARVFSG 495
            .::.|  |.::.|               .:.|..|.   |....|....::|:..|:|||||:||
Zfish   475 ANQSA--ESLASGDAGGDSIPAPAAAGVTDALCAQT---EALSVKTTVEEENKEHFVAFARVYSG 534

  Fly   496 TLKRGMELFNLSPKHDPRQPTHR-KEG--------EAPYASRVTIGDLYMFMGGELQLLDEVPAG 551
            .:::|.::|.|.||:||...... .||        ..|:.|..|:..||:.||.||:.|||||:|
Zfish   535 VVRKGQKVFVLGPKYDPSLALRALPEGCSVSDVLPSIPHMSYCTVDSLYLLMGRELEELDEVPSG 599

  Fly   552 NIVGIGGLESHIVKTATLSSSLDCTSFSELSVMATPILRVAIEPVQPQDMPKLVKGLKLLNQADA 616
            |::||||||..|:|:||:|:|..|..|:.|:..||||:|||:||..|.:|||||:|:|||||||.
Zfish   600 NVLGIGGLEDVILKSATISTSPACPPFTPLNFEATPIVRVAVEPKHPSEMPKLVRGMKLLNQADP 664

  Fly   617 CVQVSVAPTGEHVITTLGEVHVEKCVHDLEQSYAKIKVNVSKPIVSFRETIVPAATVDMVNE--- 678
            |.:|.:..|||||:.|.||||:::|:.||.:.:|||:::.||||:.||||:|....||||||
Zfish   665 CAEVLIQETGEHVLVTAGEVHLQRCLDDLRERFAKIEISSSKPIIPFRETVVRPPRVDMVNEDLG 729

  Fly   679 -----AIVKTAEDKDVSKKIAVQ---------QTLNKLGTLKVIAVPLPAEAVELLETHSEFFKE 729
                 |::...:::.......||         .|.||:.|:.|.|:|||.:...|||.:.|..:.
Zfish   730 KQQKVAVIHQVKEEQSKNPECVQVDSSGLVSLTTPNKMATVGVRAIPLPEQVTCLLEDNVELIRT 794

  Fly   730 L----AAIPRNQLL--SEKWTALLASIKVKLIAALKDLQLFGLSTLSPEELVNRIWALGPRNCGT 788
            :    .::...:.|  |:|....:...||||.:.|:..:.        ...|:.|||.|||.||.
Zfish   795 MEQFNLSVREGKTLDISQKILDNIQDFKVKLESHLQGHKW--------RNAVDHIWAFGPRRCGP 851

  Fly   789 NILLN-LSDYEQPDFWSSHAKSDTDIRSKTDPRKDFNSSLVNGFQITSVAGPLCEEPMQGVCFAV 852
            ||||| :..|.:|..|..   .:|: ::::...:||::|:.:|||:.::|||:||||:.||||:|
Zfish   852 NILLNSIEGYRRPSVWQC---LETE-KTESSALRDFDNSIASGFQLATLAGPMCEEPLMGVCFSV 912

  Fly   853 LEWSIQ--------------SEGEDLNSR--------------------------GPFSGQVLTA 877
            ..|.::              |:..:||:.                          ||||||::.|
Zfish   913 ESWDMKISTPVAQQDSVDEGSQPAELNNEHSEVSPVSSSRSRSKAEAAGSSVDCYGPFSGQLIAA 977

  Fly   878 AKEVCRQAFQNQPQRLVTPMYSCNIVVNAEMLGKMYAVIGRRHGKILSGDLTQGSGNFAVTCLLP 942
            .||.||.|||.:||||:..||:|.|:..||:||::|||:.:|.|::|..::.:|:..|.:..:||
Zfish   978 VKEACRYAFQAKPQRLMAAMYTCEIMATAEVLGRVYAVLSKREGRVLQEEMKEGTDMFIIKAVLP 1042

  Fly   943 VIESFNFAQEMRKQTSGLACPQLMFSHWEVIDIDPFWLPTTEEELMHFGEKADSANRAKVYMDSV 1007
            |.|||.||.|:||:|||||.|||:|||||||..||||:||||||.:||||||||.|:|..||::|
Zfish  1043 VAESFGFADEIRKRTSGLASPQLIFSHWEVIGSDPFWVPTTEEEYLHFGEKADSTNQALKYMNAV 1107

  Fly  1008 RRRKGLFVDEQVVEHAEKQRTLSKNK 1033
            |:||||:|:|::||||||||||.|||
Zfish  1108 RKRKGLYVEEKIVEHAEKQRTLGKNK 1133

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33158	NP_788515.1	PTZ00416	15..1016	CDD:240409	503/1106 (45%)
		EF2	20..249	CDD:206672	149/245 (61%)
		EF2_II	485..572	CDD:293913	44/95 (46%)
		EF2_snRNP_III	587..658	CDD:293918	39/70 (56%)
		aeEF2_snRNP_like_IV	658..899	CDD:238839	97/304 (32%)
		eEF2_snRNP_like_C	896..974	CDD:239763	41/77 (53%)
efl1	XP_697184.5	PTZ00416	19..1116	CDD:240409	505/1112 (45%)
		EF2	38..272	CDD:206672	148/240 (62%)
		EF2_II	523..620	CDD:293913	44/96 (46%)
		EF2_snRNP_III	635..706	CDD:293918	39/70 (56%)
		aeEF2_snRNP_like_IV	706..999	CDD:238839	97/304 (32%)
		eEF2_snRNP_like_C	996..1073	CDD:239763	40/76 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581744
Domainoid	1	1.000	321	1.000	Domainoid score	I1208
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11599
Inparanoid	1	1.050	961	1.000	Inparanoid score	I316
OMA	1	1.010	-	-		QHG53952
OrthoDB	1	1.010	-	-		D140796at2759
OrthoFinder	1	1.000	-	-		FOG0004608
OrthoInspector	1	1.000	-	-		oto40424
orthoMCL	1	0.900	-	-		OOG6_102502
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3227
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.810