DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33158 and AT3G12915

DIOPT Version :9

Sequence 1:	NP_788515.1	Gene:	CG33158 / 39834	FlyBaseID:	FBgn0053158	Length:	1033	Species:	Drosophila melanogaster
Sequence 2:	NP_001154611.1	Gene:	AT3G12915 / 3768815	AraportID:	AT3G12915	Length:	820	Species:	Arabidopsis thaliana

Alignment Length:	1011	Identity:	301/1011 - (29%)
Similarity:	472/1011 - (46%)	Gaps:	228/1011 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 ILAHVDHGKTTLADSLVASNGIISQRMAGKLRYLDNRSDEQERGITMKSSSISLYYQEAEEMA-- 86
            ::|||||||:||.|||||:.|||:|..||.:|..|.|:||.|||||:||:.|||||:..:...
plant     3 VIAHVDHGKSTLTDSLVAAAGIIAQETAGDVRMTDTRADEAERGITIKSTGISLYYEMTDASLKS 67

  Fly    87 ------GNPDYLINLIDSPGHVDFSSEVSTAVRLCDGAIVVVDVVEGVGPQTRACLRQIYEEQLK 145
                  || :||||||||||||||||||:.|:|:.|||:||||.:|||..||...|||...|:::
plant    68 FTGARDGN-EYLINLIDSPGHVDFSSEVTAALRITDGALVVVDCIEGVCVQTETVLRQSLGERIR 131

  Fly   146 PVLVLNKLDRLILEKQMDPLDAYFHLCQVLEQVNAVLGSIFASDILAKEDITKKDNYESALEEVD 210
            |||.:||:||..||.::|..:||.:..:|:|..|.::.:                 :|..|  :.
plant   132 PVLTVNKMDRCFLELKVDGEEAYQNFQRVIENANVIMAT-----------------HEDPL--LG 177

  Fly   211 DSELYFSPSSGNVIFCSAYDGWAFSVRDFAAMYAKRLEMSRKDLENVLWGDFYYNSKKKEALPGA 275
            |.::|  |..|.|.|.:...||||::.:||.|||.:..:|...:...|||:.:::|..::.....
plant   178 DVQVY--PEKGTVAFSAGLHGWAFTLTNFAKMYASKFGVSESKMMERLWGENFFDSATRKWTTKT 240

  Fly   276 QEKAKKPMFVQFVLENIWSLYDIIAIRKDKDKLPGIAEKLGLKLATRDLRLTDPKLQIKAVLGQW 340
            .....|..||||..|.|..:.: ..:...||||..:.||||:::...:..|....| :|.|:..|
plant   241 GSPTCKRGFVQFCYEPIKIMIN-TCMNDQKDKLWPMLEKLGIQMKPDEKELMGKPL-MKRVMQAW 303

  Fly   341 LPIDKSVLHMVIQHVPPPHKISDERAQRLLYPANVDLSSLPPETLELKESFTSCDANSSNVIAFV 405
            ||...::|.|:|.|:|.|:.....|.:. ||...:|        .:...:..:||.:.. ::.:|
plant   304 LPASTALLEMMIFHLPSPYTAQRYRVEN-LYEGPLD--------DKYAAAIRNCDPDGP-LMLYV 358

  Fly   406 SKMTPVHITHLPQNRPKRLTDQEVQQRRDEVRRRIEERKQQSEQAELEKISQGVEQLSTQVVGPE 470
            |||.|.
plant   359 SKMIPA----------------------------------------------------------- 364

  Fly   471 KEESKPEEADQNEFVFIAFARVFSGTLKRGMELFNLSPKHDPRQPTHRKEGEAPYASRVTIGDLY 535
                    :|:..  |.||.||||||:..||::..:.|.:.|        ||..        |||
plant   365 --------SDKGR--FFAFGRVFSGTVSTGMKVRIMGPNYVP--------GEKK--------DLY 403

  Fly   536 --------MFMGGELQLLDEVPAGNIVGIGGLESHIVKTATLSS--SLDCTSFSELSVMATPILR 590
                    ::||.:.:.:::||.||.|.:.||:..|.|..||::  .:|......:....:|::|
plant   404 VKSVQRTVIWMGKKQETVEDVPCGNTVAMVGLDQFITKNGTLTNEKEVDAHPLRAMKFSVSPVVR 468

  Fly   591 VAIEPVQPQDMPKLVKGLKLLNQADACVQVSVAPTGEHVITTLGEVHVEKCVHDLEQSYAKIKVN 655
            ||::.....|:||||:|||.|.::|..|..::..:|||::...||:|:|.||.||:.......:.
plant   469 VAVKCKLASDLPKLVEGLKRLAKSDPMVLCTMEESGEHIVAGAGELHIEICVKDLQDFMGGADII 533

  Fly   656 VSKPIVSFRETIVPAATVDMVNEAIVKTAEDKDVSKKIAVQQTLNKLGTLKVIAVPLP---AEAV 717
            ||.|:||.|||:.                   :.|.:..:.::.||...|.:.|.|:.   |||:
plant   534 VSDPVVSLRETVF-------------------ERSCRTVMSKSPNKHNRLYMEARPMEDGLAEAI 579

  Fly   718 ELLETHSEFFKELAAIPRNQLLSEKWTALLASIKVKLIAALKDLQLFGLSTLSPEELVNRIWALG 782
            :          |....|.:.          ..|:.|::|     :.||..    ::|..:|||.|
plant   580 D----------EGRIGPSDD----------PKIRSKILA-----EEFGWD----KDLAKKIWAFG 615

  Fly   783 PRNCGTNILLNLSDYEQPDFWSSHAKSDTDIRSKTDPRKDFNSSLVNGFQITSVAGPLCEEPMQG 847
            |...|.|:::                   |:........:...|:|.|||..|..|||.||.|:|
plant   616 PDTTGPNMVV-------------------DMCKGVQYLNEIKDSVVAGFQWASKEGPLAEENMRG 661

  Fly   848 VCFAVLEWSIQSEGEDLNSRGPFSGQVLTAAKEVCRQAFQNQPQRLVTPMYSCNIVVNAEMLGKM 912
            ||:.|.:..:.:   |...||  .||:::.|:.....:......||:.|:|...|......||.:
plant   662 VCYEVCDVVLHA---DAIHRG--CGQMISTARRAIYASQLTAKPRLLEPVYMVEIQAPEGALGGI 721

  Fly   913 YAVIGRRHGKILSGDLTQGSGNFAVTCLLPVIESFNFAQEMRKQTSGLACPQLMFSHWEVIDIDP 977
            |:|:.::.|.:.......|:..:.:...|||:|||.|:.::|..|||.|.||.:|.||:::..||
plant   722 YSVLNQKRGHVFEEMQRPGTPLYNIKAYLPVVESFGFSGQLRAATSGQAFPQCVFDHWDMMSSDP 786

  Fly   978 FWLPTTEEELMHFGEKADSANRAKVYMDSVRRRKGL 1013
            .                ::.::|...:..:|:||||
plant   787 L----------------ETGSQAATLVADIRKRKGL 806

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33158	NP_788515.1	PTZ00416	15..1016	CDD:240409	301/1011 (30%)
		EF2	20..249	CDD:206672	107/232 (46%)
		EF2_II	485..572	CDD:293913	31/96 (32%)
		EF2_snRNP_III	587..658	CDD:293918	27/70 (39%)
		aeEF2_snRNP_like_IV	658..899	CDD:238839	56/243 (23%)
		eEF2_snRNP_like_C	896..974	CDD:239763	26/77 (34%)
AT3G12915	NP_001154611.1	PLN00116	1..820	CDD:177730	301/1011 (30%)
		EF2	1..209	CDD:206672	105/227 (46%)
		EF2_II	353..448	CDD:293913	37/180 (21%)
		EF2_snRNP_III	465..536	CDD:293918	27/70 (39%)
		aeEF2_snRNP_like_IV	536..707	CDD:238839	56/242 (23%)
		eEF2_snRNP_like_C	704..782	CDD:239763	26/77 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0480
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D140796at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820