DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG33158 and Dgp-1

DIOPT Version :9

Sequence 1:	NP_788515.1	Gene:	CG33158 / 39834	FlyBaseID:	FBgn0053158	Length:	1033	Species:	Drosophila melanogaster
Sequence 2:	NP_611302.1	Gene:	Dgp-1 / 37080	FlyBaseID:	FBgn0027836	Length:	669	Species:	Drosophila melanogaster

Alignment Length:	410	Identity:	72/410 - (17%)
Similarity:	131/410 - (31%)	Gaps:	146/410 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 SDLVLLQRRRQQ--------VR-----------NICILAHVDHGKTTLADSLVASNGIISQRMAG 52
            :|:|.|:.||.:        :|           .:.::.:||.||:||..  |.::|.:......
  Fly   112 ADVVKLRERRAEKGQSAQFLIRKHIDTTDFMEIRVAVVGNVDAGKSTLLG--VLTHGELDNGRGH 174

  Fly    53 KLRYLDNRSDEQERGITMKSSSISLYYQEAEEMAGNPDYLINLIDSPGHVDFSSEVSTAVRLCDG 117
            ..:.|.....|.|.|.|....:..|.:.....:...||:        ||:|:       |::|:.
  Fly   175 ARQRLFRHKHEIESGRTSSVGNDILGFDGVGNVVNKPDH--------GHLDW-------VKICEN 224

  Fly   118 AIVVVDVVEGVGPQ-----------------------TRACLRQIYEEQL-------KPV-LVLN 151
            :..|:..::..|.:                       ..|.:..:.:|.|       .|| :|:.
  Fly   225 SAKVITFIDLAGHERYLKTTVFGMTGHAPDFGMLMIGANAGIIGMTKEHLGLALALAVPVFVVVT 289

  Fly   152 KLDRL---ILEKQMD--------------PLDAYFHLCQVLEQVNAV---LGSIFASDILAKEDI 196
            |:|..   :|::.|.              |:....|...||...|.|   |..||....:..:::
  Fly   290 KIDMCPANVLQENMKLLFKMLKSQGCRKVPVVVRSHDDVVLSATNFVSERLCPIFQVSNVTGDNL 354

  Fly   197 -----------TKKDNYESALEEVDDSELYFSPSSGNVIFCSAYDG----------WAFSVRDFA 240
                       |:....||...|....::|..|..|.|:..:...|          ...:|..|.
  Fly   355 ELLKMFLNLLSTRMPGSESLPAEFQIDDVYAVPGVGTVVSGTCLQGTIRLNDCLMLGPDAVGSFV 419

  Fly   241 AMYAKRLEMSRKDLENVLWGDFYYNSKKKEALPGAQEKAKKPMFVQFVLENIWSLYDIIAIRKDK 305
            .:..|.:...|.::..|..|                      ....|.|:.|...|    :||
  Fly   420 PITIKSIHRKRMNVARVRCG----------------------QTASFALKKIKRAY----LRK-- 456

  Fly   306 DKLPGIAEKLGLKLATRDLR 325
                      |:.:.::||:
  Fly   457 ----------GMVMVSQDLK 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG33158	NP_788515.1	PTZ00416	15..1016	CDD:240409	69/402 (17%)
		EF2	20..249	CDD:206672	55/311 (18%)
		EF2_II	485..572	CDD:293913
		EF2_snRNP_III	587..658	CDD:293918
		aeEF2_snRNP_like_IV	658..899	CDD:238839
		eEF2_snRNP_like_C	896..974	CDD:239763
Dgp-1	NP_611302.1	GTPBP1	38..555	CDD:227583	72/410 (18%)
		GTPBP1_like	145..367	CDD:206728	42/238 (18%)
		GTPBP_II	376..462	CDD:293895	19/123 (15%)
		GTPBP_III	468..553	CDD:294007
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464652
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930