Protein Alignment CG33158 and eEF2

DIOPT Version :9

• Sequence 1: NP_788515.1
• Gene: CG33158 / 39834
• FlyBaseID: FBgn0053158
• Length: 1033
• Species: Drosophila melanogaster
• Sequence 2: NP_525105.2
• Gene: eEF2 / 35422
• FlyBaseID: FBgn0000559
• Length: 844
• Species: Drosophila melanogaster
• Alignment Length: 1021
• Identity: 302/1021 - (29%)
• Similarity: 486/1021 - (47%)
• Gaps: 221/1021 - (21%)

  Fly    12 LQRRRQQVRNICILAHVDHGKTTLADSLVASNGIISQRMAGKLRYLDNRSDEQERGITMKSSSIS 76
            |..:::.:||:.::|||||||:||.||||:..|||:...||:.|:.|.|.|||||.||:||::||
  Fly    12 LMDKKRNIRNMSVIAHVDHGKSTLTDSLVSKAGIIAGAKAGETRFTDTRKDEQERCITIKSTAIS 76

  Fly    77 LYYQEAEE---MAGNPD--------YLINLIDSPGHVDFSSEVSTAVRLCDGAIVVVDVVEGVGP 130
            :|::..|:   ...:||        :|||||||||||||||||:.|:|:.|||:||||.|.||..
  Fly    77 MYFEVEEKDLVFITHPDQREKECKGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCV 141

  Fly   131 QTRACLRQIYEEQLKPVLVLNKLDRLILEKQMDPLDAYFHLCQVLEQVNAVLGSIFASDILAKED 195
            ||...|||...|::||:|.:||:||.:||.|:|..:.|....:::|.||.::.:
  Fly   142 QTETVLRQAIAERIKPILFMNKMDRALLELQLDAEELYQTFQRIVENVNVIIAT----------- 195

  Fly   196 ITKKDNYESALEEVDD----SELYFSPSSGNVIFCSAYDGWAFSVRDFAAMYAKRLEMSRKDLEN 256
                  |.      ||    .|:...||.|:|.|.|...||||:::.|:.||:::.::....|.|
  Fly   196 ------YN------DDGGPMGEVRVDPSKGSVGFGSGLHGWAFTLKQFSEMYSEKFKIDVVKLMN 248

  Fly   257 VLWGDFYYNSKKKEALPGAQEKAKKPMFVQFVLENIWSLYDIIAIRKDKDKLPGIAEKLGLKLAT 321
            .|||:.::|:|.|: ....:|...|..|..::|:.|:.::|.|...| |:::..:.||:|:.|..
  Fly   249 RLWGENFFNAKTKK-WQKQKEADNKRSFCMYILDPIYKVFDAIMNYK-KEEIGTLLEKIGVTLKH 311

  Fly   322 RDLRLTDPKLQIKAVLGQWLPIDKSVLHMVIQHVPPPHKISDERAQRLLYPANVDLSSLPPETLE 386
            .| :..|.|..:|.|:..|||..:::|.|:..|:|.| .::.:....:||..        |...|
  Fly   312 ED-KDKDGKALLKTVMRTWLPAGEALLQMIAIHLPSP-VVAQKYRMEMLYEG--------PHDDE 366

  Fly   387 LKESFTSCDANSSNVIAFVSKMTPVHITHLPQNRPKRLTDQEVQQRRDEVRRRIEERKQQSEQAE 451
            ...:..|||.:.. ::.::|||.|.
  Fly   367 AAIAVKSCDPDGP-LMMYISKMVPT---------------------------------------- 390

  Fly   452 LEKISQGVEQLSTQVVGPEKEESKPEEADQNEFVFIAFARVFSGTLKRGMELFNLSPKHDPRQPT 516
                                       :|:..  |.||.|||:|.:..|.:...:.|.:.|
  Fly   391 ---------------------------SDKGR--FYAFGRVFAGKVATGQKCRIMGPNYTP---- 422

  Fly   517 HRKEGEAPYASRVTIGDLYMFMGGELQLLDEVPAGNIVGIGGLESHIVKTATLSSSLDCTSFSEL 581
            .:||.....|.:.||    :.||..::.:::||:|||.|:.|::..:|||.|:::..|..:...:
  Fly   423 GKKEDLYEKAIQRTI----LMMGRYVEAIEDVPSGNICGLVGVDQFLVKTGTITTFKDAHNMKVM 483

  Fly   582 SVMATPILRVAIEPVQPQDMPKLVKGLKLLNQADACVQVSVAPTGEHVITTLGEVHVEKCVHDLE 646
            ....:|::|||:||..|.|:||||:|||.|.::|..||..:..:|||:|...||:|:|.|:.|||
  Fly   484 KFSVSPVVRVAVEPKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHIIAGAGELHLEICLKDLE 548

  Fly   647 QSYAKIKVNVSKPIVSFRETIVPAATVDMVNEAIVKTAEDKDVSKKIAVQQTLNKLGTLKVIAVP 711
            :.:|.|.:..|.|:||:|||:                :|:.|   ::.:.::.||...|.:.|:|
  Fly   549 EDHACIPLKKSDPVVSYRETV----------------SEESD---QMCLSKSPNKHNRLLMKALP 594

  Fly   712 LPAEAVELLE----THSEFFKELAAIPRNQLLSEKWTALLASIKVKLIAALKDLQLFGLSTLSPE 772
            :|....|.::    :..:.||     .|.:.||||:...:...:
  Fly   595 MPDGLPEDIDNGDVSAKDEFK-----ARARYLSEKYDYDVTEAR--------------------- 633

  Fly   773 ELVNRIWALGPRNCGTNILLNLSDYEQPDFWSSHAKSDTDIRSKTDPRKDFNSSLVNGFQITSVA 837
                :||..||...|.|.:|                   |.........:...|:|.|||..|..
  Fly   634 ----KIWCFGPDGTGPNFIL-------------------DCTKSVQYLNEIKDSVVAGFQWASKE 675

  Fly   838 GPLCEEPMQGVCFAVLEWSIQSEGEDLNSRGPFSGQVLTAAKEVCRQAFQNQPQRLVTPMYSCNI 902
            |.|.:|.::||.|.:.:.::.:   |...||  .||::...:.....|......||:.|:|.|.|
  Fly   676 GILADENLRGVRFNIYDVTLHA---DAIHRG--GGQIIPTTRRCLYAAAITAKPRLMEPVYLCEI 735

  Fly   903 VVNAEMLGKMYAVIGRRHGKILSGDLTQGSGNFAVTCLLPVIESFNFAQEMRKQTSGLACPQLMF 967
            ......:|.:|.|:.||.|.:...:...|:..|.|...|||.|||.|..::|..|.|.|.||.:|
  Fly   736 QCPEVAVGGIYGVLNRRRGHVFEENQVVGTPMFVVKAYLPVNESFGFTADLRSNTGGQAFPQCVF 800

  Fly   968 SHWEVIDIDPFWLPTTEEELMHFGEKADSANRAKVYMDSVRRRKGL 1013
            .||:|:..||                ::.:::....:...|:||||
  Fly   801 DHWQVLPGDP----------------SEPSSKPYAIVQDTRKRKGL 830

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33158	NP_788515.1	PTZ00416	15..1016	CDD:240409	301/1018 (30%)
		EF2	20..249	CDD:206672	105/243 (43%)
		EF2_II	485..572	CDD:293913	28/86 (33%)
		EF2_snRNP_III	587..658	CDD:293918	33/70 (47%)
		aeEF2_snRNP_like_IV	658..899	CDD:238839	51/244 (21%)
		eEF2_snRNP_like_C	896..974	CDD:239763	30/77 (39%)
eEF2	NP_525105.2	PTZ00416	1..844	CDD:240409	302/1021 (30%)
		EF2	20..236	CDD:206672	104/238 (44%)
		EF2_snRNP_like_II	380..474	CDD:293901	33/170 (19%)
		EF2_snRNP_III	489..560	CDD:293918	33/70 (47%)
		aeEF2_snRNP_like_IV	560..732	CDD:238839	51/244 (21%)
		eEF2_snRNP_like_C	728..807	CDD:239763	30/78 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464651
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0480
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D140796at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR42908
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850