Protein Alignment CG33158 and eef2b

DIOPT Version :9

• Sequence 1: NP_788515.1
• Gene: CG33158 / 39834
• FlyBaseID: FBgn0053158
• Length: 1033
• Species: Drosophila melanogaster
• Sequence 2: NP_956752.2
• Gene: eef2b / 326929
• ZFINID: ZDB-GENE-030131-5128
• Length: 858
• Species: Danio rerio
• Alignment Length: 1039
• Identity: 310/1039 - (29%)
• Similarity: 476/1039 - (45%)
• Gaps: 249/1039 - (23%)

  Fly    15 RRQQVRNICILAHVDHGKTTLADSLVASNGIISQRMAGKLRYLDNRSDEQERGITMKSSSISLYY 79
            ::..:||:.::|||||||:||.||||:..|||:...||:.|:.|.|.|||||.||:||::||:||
Zfish    15 KKSNIRNMSVIAHVDHGKSTLTDSLVSKAGIIASARAGETRFTDTRKDEQERCITIKSTAISMYY 79

  Fly    80 QEAE-------EMAGNPDYLINLIDSPGHVDFSSEVSTAVRLCDGAIVVVDVVEGVGPQTRACLR 137
            :..|       :......:|||||||||||||||||:.|:|:.|||:||||.|.||..||...||
Zfish    80 ELTENDLAFIKQCKDGSGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLR 144

  Fly   138 QIYEEQLKPVLVLNKLDRLILEKQMDPLDAYFHLCQVLEQVNAVLGSIFASDILAKEDITKKDNY 202
            |...|::||||::||:||.:||.|::|.:.|....:::|.||.:: |.:..|
Zfish   145 QAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVII-STYGED------------- 195

  Fly   203 ESALEEVDDSELYFSPSSGNVIFCSAYDGWAFSVRDFAAMY-----------------AKRLEMS 250
                |......:...|..|.|.|.|...||||:::.||.||                 .|::|
Zfish   196 ----EGGPMGNIMIDPVIGTVGFGSGLHGWAFTLKQFAEMYVAKFASKGEAQLSPADRCKKVE-- 254

  Fly   251 RKDLENVLWGDFYYN---SKKKEALPGAQEKAKKPMFVQFVLENIWSLYDIIAIRKDKDKLPGIA 312
              |:...||||.|::   .|..:...|...|.....|.|.:|:.|:.::|.|...| |::...:.
Zfish   255 --DMMKKLWGDRYFDPAGGKFTKTANGPDGKKYPRTFAQLILDPIFKVFDAIMNFK-KEETAKLI 316

  Fly   313 EKLGLKLATRDLRLTDPKLQIKAVLGQWLPIDKSVLHMVIQHVPPPHKISDERAQRLLYPANVDL 377
            |||.:||.|.| :..:.|..:|||:.:|||..:::|.|:..|:|.|......|.: |||..
Zfish   317 EKLDIKLDTED-KDKEGKPLLKAVMRRWLPAGEALLQMITIHLPSPVTAQKYRCE-LLYEG---- 375

  Fly   378 SSLPPETLELKESFTSCDANSSNVIAFVSKMTPVHITHLPQNRPKRLTDQEVQQRRDEVRRRIEE 442
                |...|......:||.... ::.::|||.|.                     .|:.|
Zfish   376 ----PGDDEAAMGIKNCDPKGP-LMMYISKMVPT---------------------TDKGR----- 409

  Fly   443 RKQQSEQAELEKISQGVEQLSTQVVGPEKEESKPEEADQNEFVFIAFARVFSGTLKRGMELFNLS 507
                                                       |.||.|||||.:..|:::..:.
Zfish   410 -------------------------------------------FYAFGRVFSGVVSTGLKVRIMG 431

  Fly   508 PKHDPRQPTHRKEGEAPYASRVTIGDLY--------MFMGGELQLLDEVPAGNIVGIGGLESHIV 564
            |.:.|    .:||            |||        :.||..::.:::||.|||||:.|::..:|
Zfish   432 PNYTP----GKKE------------DLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLV 480

  Fly   565 KTATLSSSLDCTSFSELSVMATPILRVAIEPVQPQDMPKLVKGLKLLNQADACVQVSVAPTGEHV 629
            ||.|:::.....:...:....:|::|||:|...|.|:||||:|||.|.::|..||..:..:|||:
Zfish   481 KTGTITTFDQAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHI 545

  Fly   630 ITTLGEVHVEKCVHDLEQSYAKIKVNVSKPIVSFRETIVPAATVDMVNEAIVKTAEDKDVSKKIA 694
            |...||:|:|.|:.|||:.:|.|.:..|.|:||:|||:               :||    |.::.
Zfish   546 IAGAGELHLEICLKDLEEDHACIPLKKSDPVVSYRETV---------------SAE----SDQMC 591

  Fly   695 VQQTLNKLGTLKVIAVPLP---AEAVELLETHSEFFKELAAIPRNQLLSEK--WTALLASIKVKL 754
            :.::.||...|.:.|.|.|   ||.::..:..|.  :||..  |.:.|::|  |....|
Zfish   592 LSKSPNKHNRLYMKARPFPDGLAEDIDKGDVSSR--QELKT--RARYLADKYEWEVTEA------ 646

  Fly   755 IAALKDLQLFGLSTLSPEELVNRIWALGPRNCGTNILLNLSDYEQPDFWSSHAKSDTDIRSKTDP 819
                                 .:||..||...|.|:|:                   |:......
Zfish   647 ---------------------RKIWCFGPDGTGPNMLV-------------------DVTKGVQY 671

  Fly   820 RKDFNSSLVNGFQITSVAGPLCEEPMQGVCFAVLEWSIQSEGEDLNSRGPFSGQVLTAAKEVCRQ 884
            ..:...|:|.|||..:..|.||||.|:.|.|.:.:.::.:   |...||  .||::..|:.|...
Zfish   672 LNEIKDSVVAGFQWATKEGALCEENMRAVRFDIHDVTLHT---DAIHRG--GGQIIPTARRVLYA 731

  Fly   885 AFQNQPQRLVTPMYSCNIVVNAEMLGKMYAVIGRRHGKILSGDLTQGSGNFAVTCLLPVIESFNF 949
            .......||:.|:|...|....:::|.:|.|:.|:.|.:.......|:..|.|...|||.|||.|
Zfish   732 CQLTAEPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVMGTPMFVVKAYLPVNESFGF 796

  Fly   950 AQEMRKQTSGLACPQLMFSHWEVIDIDPFWLPTTEEELMHFGEKADSANRAKVYMDSVRRRKGL 1013
            ..::|..|.|.|.||.:|.||:::..||                .|:|::....:...|:||||
Zfish   797 TADLRSNTGGQAFPQCVFDHWQILPGDP----------------KDAASKPCQIVADTRKRKGL 844

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33158	NP_788515.1	PTZ00416	15..1016	CDD:240409	310/1039 (30%)
		EF2	20..249	CDD:206672	105/252 (42%)
		EF2_II	485..572	CDD:293913	30/94 (32%)
		EF2_snRNP_III	587..658	CDD:293918	32/70 (46%)
		aeEF2_snRNP_like_IV	658..899	CDD:238839	56/245 (23%)
		eEF2_snRNP_like_C	896..974	CDD:239763	27/77 (35%)
eef2b	NP_956752.2	PTZ00416	1..858	CDD:240409	310/1039 (30%)
		EF2	20..233	CDD:206672	103/230 (45%)
		EF2_snRNP_like_II	394..488	CDD:293901	36/178 (20%)
		EF2_snRNP_III	503..574	CDD:293918	32/70 (46%)
		aeEF2_snRNP_like_IV	574..746	CDD:238839	56/245 (23%)
		eEF2_snRNP_like_C	742..821	CDD:239763	27/78 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D140796at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920