Protein Alignment CG33158 and Efl1

DIOPT Version :9

• Sequence 1: NP_788515.1
• Gene: CG33158 / 39834
• FlyBaseID: FBgn0053158
• Length: 1033
• Species: Drosophila melanogaster
• Sequence 2: NP_001101004.1
• Gene: Efl1 / 308789
• RGDID: 1306521
• Length: 1127
• Species: Rattus norvegicus
• Alignment Length: 1150
• Identity: 519/1150 - (45%)
• Similarity: 723/1150 - (62%)
• Gaps: 143/1150 - (12%)

  Fly     3 VVEGSD-LVLLQRRRQQVRNICILAHVDHGKTTLADSLVASNGIISQRMAGKLRYLDNRSDEQER 66
            |:.|.| ::.||:....:||||:|||||||||||||.|::||||||.|:||||||:|:|.|||.|
  Rat     2 VLSGLDKMIQLQKNTANIRNICVLAHVDHGKTTLADCLISSNGIISSRLAGKLRYMDSREDEQVR 66

  Fly    67 GITMKSSSISLYYQEAEEMAGNPDYLINLIDSPGHVDFSSEVSTAVRLCDGAIVVVDVVEGVGPQ 131
            |||||||:|||:|.|     |:.:|||||||||||||||||||||||:|||.|:|||.||||.||
  Rat    67 GITMKSSAISLHYAE-----GSEEYLINLIDSPGHVDFSSEVSTAVRICDGCIIVVDAVEGVCPQ 126

  Fly   132 TRACLRQIYEEQLKPVLVLNKLDRLILEKQMDPLDAYFHLCQVLEQVNAVLGSIFASDIL----- 191
            |:|.|||.:.|.::||||:||:||||:|.:..|.:||.||..:|.|:||:.|::|.|.:|
  Rat   127 TQAVLRQAWLENIRPVLVINKIDRLIVELKFTPQEAYSHLKNILGQINALTGTLFTSKVLEERAE 191

  Fly   192 ------AKEDITKKD---NYESALEEVDDSELYFSPSSGNVIFCSAYDGWAFSVRDFAAMYAKRL 247
                  ||....:.|   ::.:.||:||||:|||||..|||:|.||.|||.|.:..||.:|::::
  Rat   192 RETESQAKSHSEQGDQVYDWSTGLEDVDDSQLYFSPEQGNVVFTSAIDGWGFGIEHFARIYSQKI 256

  Fly   248 EMSRKDLENVLWGDFYYNSKKKEALPGAQEKAKKPMFVQFVLENIWSLYDIIAIRKDKDKLPGIA 312
            .:.::.|...||||:|.|.|.|:.:...|.|.|||:|||.:|||||||||.: ::|||:|:..|.
  Rat   257 GIKKEVLLKTLWGDYYINMKAKKIMKVDQAKGKKPLFVQLILENIWSLYDAV-LKKDKEKVDKIV 320

  Fly   313 EKLGLKLATRDLRLTDPKLQIKAVLGQWLPIDKSVLHMVIQHVPPPHKISDERAQRLLYPANVDL 377
            ..||||:..|:.|.:|||:||.|:..|||||..:||.||.|.:|.|..::.||.::|:...:...
  Rat   321 TSLGLKIGAREARHSDPKVQINAICSQWLPISHAVLAMVCQKLPSPLDMTSERVEKLMCTGSQTF 385

  Fly   378 SSLPPETLELKESFTSCDA-NSSNVIAFVSKMTPVHITHLPQNRPKRLTDQEVQQRRDEVRRRIE 441
            .|||.||..||.:|..|.: :::.||.|||||..|.:..||||:|:.||.:|:.|||:..|:|..
  Rat   386 ESLPLETQALKAAFMKCGSEDTAPVIIFVSKMFAVDVKALPQNKPRPLTQEEMAQRRERARQRHA 450

  Fly   442 ERKQQSEQAELEKISQGVEQLSTQVVGPEKEESKPEEAD-------------QNEFVFIAFARVF 493
            |:...::....:..:|....|.|   .|:::|.:.||.|             .::..||||||||
  Rat   451 EKLAAAQGQAPQGPTQDGGALET---SPQEDEPRGEEPDMTSVSRQPAPQEESSQEAFIAFARVF 512

  Fly   494 SGTLKRGMELFNLSPKHDP-----RQPTHRKEG---------EAPYASRVTIGDLYMFMGGELQL 544
            ||..:||.::|.|.||:.|     |.|    :|         ..|:.:..|:.:||:.||.||:.
  Rat   513 SGVARRGKKIFVLGPKYSPVDFLQRVP----QGFSAPLEDLPPVPHMACCTLENLYLLMGRELED 573

  Fly   545 LDEVPAGNIVGIGGLESHIVKTATLSSSLDCTSFSELSVMATPILRVAIEPVQPQDMPKLVKGLK 609
            |:|||.||::|||||:..::|:|||.|...|..|..|:..||||:|||:||..|.:||:||||:|
  Rat   574 LEEVPPGNVLGIGGLQDSVLKSATLCSLPSCPPFIPLNFEATPIVRVAVEPKHPSEMPQLVKGMK 638

  Fly   610 LLNQADACVQVSVAPTGEHVITTLGEVHVEKCVHDLEQSYAKIKVNVSKPIVSFRETIVPAATVD 674
            ||||||.|||:.:..|||||:.|.||||:::|:.||.:.:|||.::||:||:.|||||.....||
  Rat   639 LLNQADPCVQILIQETGEHVLVTAGEVHLQRCLDDLRERFAKIHISVSEPIIPFRETITKPPKVD 703

  Fly   675 MVNEAI---VKTA-------EDKDVSKKIAVQQ-------TLNKLGTLKVIAVPLPAEAVELLET 722
            ||||.|   .|.|       |...:.:.|.|..       |.|||.||.|.|:|||.|...:||.
  Rat   704 MVNEEIGRQQKVAVIHQTKEEQSKIPEGILVDSDGLITIPTPNKLATLSVRAIPLPEEVTRILEE 768

  Fly   723 HSEFFKELAAIP------RN-QLLSEKWTALLASIKVKLIAALKDLQLFGLSTLSPEELVNRIWA 780
            :|:..:.:..:.      || |.:.:|....:...|.||     :..|.|...   ...|::||:
  Rat   769 NSDLIRSMELLTSSLNEGRNTQAIHQKTQEKIWEFKGKL-----EKHLTGRKW---RNTVDQIWS 825

  Fly   781 LGPRNCGTNILLNLSDYEQPDFWSSHAKSDTDIRSKTDPRKDFNSSLVNGFQITSVAGPLCEEPM 845
            .|||.||.|||::.|:..|...||..|..::...|:.   :||.:|:|:|||:.:::||:||||:
  Rat   826 FGPRKCGPNILVSRSEDFQSSVWSGPAGRESKEASRF---RDFGNSIVSGFQLATLSGPMCEEPL 887

  Fly   846 QGVCFAVLEWSI-----------QSEGE-DLNSR------------------------------- 867
            .||||.:.:|.:           ||:|: ||...
  Rat   888 MGVCFVLEKWELNKCAEPGASDKQSQGQCDLTGEGQEKSKTCPVGDENQEQQDGYSEPFEETSQK 952

  Fly   868 ---------GPFSGQVLTAAKEVCRQAFQNQPQRLVTPMYSCNIVVNAEMLGKMYAVIGRRHGKI 923
                     ||||||::...||.||.|.|.:||||:..||:|:|:..:::||::|||:.:|.|::
  Rat   953 GDSPVIDCYGPFSGQLIATMKEACRYALQVKPQRLMAAMYTCDIMATSDVLGRVYAVLSKREGRV 1017

  Fly   924 LSGDLTQGSGNFAVTCLLPVIESFNFAQEMRKQTSGLACPQLMFSHWEVIDIDPFWLPTTEEELM 988
            |..::.:|:..|.:..:|||.|||.||.|:||:|||||.|||:|||||||..||||:||||||.:
  Rat  1018 LQEEMKEGTDMFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEVIPSDPFWVPTTEEEYL 1082

  Fly   989 HFGEKADSANRAKVYMDSVRRRKGLFVDEQVVEHAEKQRTLSKNK 1033
            ||||||||.|:|:.||::||:||||:|:|::||||||||||||||
  Rat  1083 HFGEKADSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSKNK 1127

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33158	NP_788515.1	PTZ00416	15..1016	CDD:240409	498/1118 (45%)
		EF2	20..249	CDD:206672	143/242 (59%)
		EF2_II	485..572	CDD:293913	43/100 (43%)
		EF2_snRNP_III	587..658	CDD:293918	41/70 (59%)
		aeEF2_snRNP_like_IV	658..899	CDD:238839	100/316 (32%)
		eEF2_snRNP_like_C	896..974	CDD:239763	39/77 (51%)
Efl1	NP_001101004.1	PTZ00416	1..1110	CDD:240409	503/1131 (44%)
		EF2	20..253	CDD:206672	142/237 (60%)
		EF2_II	505..600	CDD:293913	43/98 (44%)
		EF2_snRNP_III	616..687	CDD:293918	41/70 (59%)
		aeEF2_snRNP_like_IV	687..993	CDD:238839	100/316 (32%)
		eEF2_snRNP_like_C	990..1068	CDD:239763	39/77 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341723
Domainoid	1	1.000	289	1.000	Domainoid score	I1497
eggNOG	1	0.900	-	-		E1_COG0480
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11599
Inparanoid	1	1.050	938	1.000	Inparanoid score	I331
OMA	1	1.010	-	-		QHG53952
OrthoDB	1	1.010	-	-		D140796at2759
OrthoFinder	1	1.000	-	-		FOG0004608
OrthoInspector	1	1.000	-	-		oto97412
orthoMCL	1	0.900	-	-		OOG6_102502
Panther	1	1.100	-	-	LDO	PTHR42908
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3227
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.770