Protein Alignment CG33158 and Eef2

DIOPT Version :10

• Sequence 1: NP_788515.1
• Gene: CG33158 / 39834
• FlyBaseID: FBgn0053158
• Length: 1033
• Species: Drosophila melanogaster
• Sequence 2: NP_058941.1
• Gene: Eef2 / 29565
• RGDID: 61979
• Length: 858
• Species: Rattus norvegicus
• Alignment Length: 1037
• Identity: 314/1037 - (30%)
• Similarity: 482/1037 - (46%)
• Gaps: 245/1037 - (23%)

  Fly    15 RRQQVRNICILAHVDHGKTTLADSLVASNGIISQRMAGKLRYLDNRSDEQERGITMKSSSISLYY 79
            ::..:||:.::|||||||:||.||||...|||:...||:.|:.|.|.|||||.||:||::|||:|
  Rat    15 KKANIRNMSVIAHVDHGKSTLTDSLVCKAGIIASARAGETRFTDTRKDEQERCITIKSTAISLFY 79

  Fly    80 QEAE-------EMAGNPDYLINLIDSPGHVDFSSEVSTAVRLCDGAIVVVDVVEGVGPQTRACLR 137
            :.:|       :......:|||||||||||||||||:.|:|:.|||:||||.|.||..||...||
  Rat    80 ELSENDLNFIKQSKDGSGFLINLIDSPGHVDFSSEVTAALRVTDGALVVVDCVSGVCVQTETVLR 144

  Fly   138 QIYEEQLKPVLVLNKLDRLILEKQMDPLDAYFHLCQVLEQVNAVLGSIFASDILAKEDITKKDNY 202
            |...|::||||::||:||.:||.|::|.:.|....:::|.||.::.:                 |
  Rat   145 QAIAERIKPVLMMNKMDRALLELQLEPEELYQTFQRIVENVNVIIST-----------------Y 192

  Fly   203 ESALEEVDDSELYFSPSSGNVIFCSAYDGWAFSVRDFAAMY-----------------AKRLEMS 250
            ... |......:...|..|.|.|.|...||||:::.||.||                 ||::|
  Rat   193 GEG-ESGPMGNIMIDPVLGTVGFGSGLHGWAFTLKQFAEMYVAKFAAKGEGQLGAAERAKKVE-- 254

  Fly   251 RKDLENVLWGDFYY---NSKKKEALPGAQEKAKKPMFVQFVLENIWSLYDIIAIRKDKDKLPGIA 312
              |:...||||.|:   |.|..::......|.....|.|.:|:.|:.::|.| :...|::...:.
  Rat   255 --DMMKKLWGDRYFDPANGKFSKSANSPDGKKLPRTFCQLILDPIFKVFDAI-MNFRKEETAKLI 316

  Fly   313 EKLGLKLATRDLRLTDPKLQIKAVLGQWLPIDKSVLHMVIQHVPPPHKISDERAQRLLYPANVDL 377
            |||.:||.:.| :..:.|..:|||:.:|||...::|.|:..|:|.|......|.: |||..
  Rat   317 EKLDIKLDSED-KDKEGKPLLKAVMRRWLPAGDALLQMITIHLPSPVTAQKYRCE-LLYEG---- 375

  Fly   378 SSLPPETLELKESFTSCDANSSNVIAFVSKMTPVHITHLPQNRPKRLTDQEVQQRRDEVRRRIEE 442
               ||:. |......|||.... ::.::|||.|.
  Rat   376 ---PPDD-EAAMGIKSCDPKGP-LMMYISKMVPT------------------------------- 404

  Fly   443 RKQQSEQAELEKISQGVEQLSTQVVGPEKEESKPEEADQNEFVFIAFARVFSGTLKRGMELFNLS 507
                                                :|:..  |.||.|||||.:..|:::..:.
  Rat   405 ------------------------------------SDKGR--FYAFGRVFSGVVSTGLKVRIMG 431

  Fly   508 PKHDPRQPTHRKEGEAPYASRVTIGDLY--------MFMGGELQLLDEVPAGNIVGIGGLESHIV 564
            |.:.|    .:||            |||        :.||..::.:::||.|||||:.|::..:|
  Rat   432 PNYTP----GKKE------------DLYLKPIQRTILMMGRYVEPIEDVPCGNIVGLVGVDQFLV 480

  Fly   565 KTATLSSSLDCTSFSELSVMATPILRVAIEPVQPQDMPKLVKGLKLLNQADACVQVSVAPTGEHV 629
            ||.|:::.....:...:....:|::|||:|...|.|:||||:|||.|.::|..||..:..:|||:
  Rat   481 KTGTITTFEHAHNMRVMKFSVSPVVRVAVEAKNPADLPKLVEGLKRLAKSDPMVQCIIEESGEHI 545

  Fly   630 ITTLGEVHVEKCVHDLEQSYAKIKVNVSKPIVSFRETIVPAATVDMVNEAIVKTAEDKDVSKKIA 694
            |...||:|:|.|:.|||:.:|.|.:..|.|:||:|||:                :|:.:|   :.
  Rat   546 IAGAGELHLEICLKDLEEDHACIPIKKSDPVVSYRETV----------------SEESNV---LC 591

  Fly   695 VQQTLNKLGTLKVIAVPLP---AEAVELLETHSEFFKELAAIPRNQLLSEKWTALLASIKVKLIA 756
            :.::.||...|.:.|.|.|   ||.::..|..:.  :||.|  |.:.|:||:...:|..:
  Rat   592 LSKSPNKHNRLYMKARPFPDGLAEDIDKGEVSAR--QELKA--RARYLAEKYEWDVAEAR----- 647

  Fly   757 ALKDLQLFGLSTLSPEELVNRIWALGPRNCGTNILLNLSDYEQPDFWSSHAKSDTDIRSKTDPRK 821
                                :||..||...|.|||                   |||........
  Rat   648 --------------------KIWCFGPDGTGPNIL-------------------TDITKGVQYLN 673

  Fly   822 DFNSSLVNGFQITSVAGPLCEEPMQGVCFAVLEWSIQSEGEDLNSRGPFSGQVLTAAKEVCRQAF 886
            :...|:|.|||..:..|.||||.|:||.|.|.:.::.:   |...||  .||::..|:.....:.
  Rat   674 EIKDSVVAGFQWATKEGALCEENMRGVRFDVHDVTLHA---DAIHRG--GGQIIPTARRCLYASV 733

  Fly   887 QNQPQRLVTPMYSCNIVVNAEMLGKMYAVIGRRHGKILSGDLTQGSGNFAVTCLLPVIESFNFAQ 951
            .....||:.|:|...|....:::|.:|.|:.|:.|.:.......|:..|.|...|||.|||.|..
  Rat   734 LTAQPRLMEPIYLVEIQCPEQVVGGIYGVLNRKRGHVFEESQVAGTPMFVVKAYLPVNESFGFTA 798

  Fly   952 EMRKQTSGLACPQLMFSHWEVIDIDPFWLPTTEEELMHFGEKADSANRAKVYMDSVRRRKGL 1013
            ::|..|.|.|.||.:|.||:::..|||                |:::|....:...|:||||
  Rat   799 DLRSNTGGQAFPQCVFDHWQILPGDPF----------------DNSSRPSQVVAETRKRKGL 844

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33158	NP_788515.1	PRK13351	15..1016	CDD:481252	314/1037 (30%)
Eef2	NP_058941.1	PTZ00416	1..858	CDD:240409	314/1037 (30%)