Protein Alignment CG33158 and mEFG1

DIOPT Version :10

• Sequence 1: NP_788515.1
• Gene: CG33158 / 39834
• FlyBaseID: FBgn0053158
• Length: 1033
• Species: Drosophila melanogaster
• Sequence 2: XP_318822.5
• Gene: mEFG1 / 1279146
• VectorBaseID: AGAMI1_000113
• Length: 744
• Species: Anopheles gambiae
• Alignment Length: 1025
• Identity: 203/1025 - (19%)
• Similarity: 360/1025 - (35%)
• Gaps: 341/1025 - (33%)

  Fly    14 RRRQQVRNICILAHVDHGKTTLADSLVASNGIISQ--RMAGKLRY---LDNRSDEQERGITMKSS 73
            ::.:::|||.|.||:|.|||||.:.::...|.|.:  .:.||...   :|:...|::||||::|:
Mosquito    36 KQLEKIRNIGISAHIDSGKTTLTERILFYTGRIKEMHEVKGKDNVGATMDSMELERQRGITIQSA 100

  Fly    74 SISLYYQEAEEMAGNPDYLINLIDSPGHVDFSSEVSTAVRLCDGAIVVVDVVEGVGPQTRACLRQ 138
            :....::         |:.||:||:||||||:.||..|:|:.|||::|:..|.||..||....||
Mosquito   101 ATYTIWK---------DHNINIIDTPGHVDFTVEVERALRVLDGAVLVLCSVGGVQSQTLTVNRQ 156

  Fly   139 IYEEQLKPVLVLNKLDRLILEKQMDPLDAYFHLCQVLEQVNAVLGSIFASDILAKEDITKKDNYE 203
            :....:..:..:|||||       ...:.|    :||.|:.:.|....|   ..:..|..:.|.:
Mosquito   157 MKRYNVPCLAFINKLDR-------SGANPY----RVLGQMRSKLNHNAA---FVQLPIGVESNCK 207

  Fly   204 SALEEVDDSELYFSPSSGNVIFCSAYDGWAFSVRDFAAMYAKRLEMSRKDLENVLWGDFYYNSKK 268
            ..::.|....|||.            :.:...:|:.......|.|.:.:..|.:
Mosquito   208 GVIDLVKQRALYFE------------EPYGLKIREDEIPADMRTESAERRQELI----------- 249

  Fly   269 KEALPGAQEKAKKPMFVQFVLENIWSLYDII-AIRKDKDKLPGIAEKLGLKLATRDLRLTDPKLQ 332
             |.|....||..:    .|:.|...::.||: |||:..           ||.|...: |....|:
Mosquito   250 -EHLSNVDEKIGE----LFLEEREATVDDIMGAIRRST-----------LKRAFTPV-LVGTALK 297

  Fly   333 IKAVLGQWLPIDKSVLHMVIQHVPPPHKISDERAQRLLYPANVDLSSLPPETLELKESFTSCDAN 397
            .|.|        :.:|..|:.::|.|.::.:
Mosquito   298 NKGV--------QPLLDAVLDYLPHPGEVEN---------------------------------- 320

  Fly   398 SSNVIAFVSKMTPVHITHLPQNRPKRLTDQEVQQRRDEVRRRIEERKQQSEQAELEKISQGVEQL 462
                :|.|.|                 .|:|
Mosquito   321 ----VALVEK-----------------KDEE---------------------------------- 330

  Fly   463 STQVVGPEKEESKPEEADQNEFVFIAF------------ARVFSGTLKRGMELFNLSPKHDPRQP 515
                  |:|....|....::.||.:||            .|.:.|.|::|..:||
Mosquito   331 ------PQKVPLNPARDGKDPFVGLAFKLEAGRFGQLTYLRCYQGVLRKGDNIFN---------- 379

  Fly   516 THRKEGEAPYASRVTIGDLYMFMGGELQLLDEVPAGNIVGIGGLESHIVKTATLSSSLDCTSFSE 580
              .:.|:     ::.:..|......:::.::||.||:|..:.|::.....|...:..|:.:  .|
Mosquito   380 --TRSGK-----KIRLARLVRLHSNQMEDVNEVYAGDIFALFGVDCASGDTFVTNPKLELS--ME 435

  Fly   581 LSVMATPILRVAIEPVQPQDMPKLVKGLKLLNQADACVQVSV-APTGEHVITTLGEVHVEKCVHD 644
            ...:..|::.:||:|...:|.....|.:....:.|....... |...|.:::.:||:|:|.....
Mosquito   436 SIFVPDPVVSMAIKPTNSKDRDNFAKAIARFTKEDPTFHFEYDADVKETLVSGMGELHLEIYAQR 500

  Fly   645 LEQSYAKIKVNVSKPIVSFRETIVPAATVDMVNEAIVKTAEDKDVSKKIAVQQTLNKLGTLKVIA 709
            :|:.| ...|.:.||.|:||||::.....|.::             ||.:..|  .:...:..|.
Mosquito   501 MEREY-NCPVTLGKPKVAFRETLIGPCEFDYLH-------------KKQSGGQ--GQYARVSGIL 549

  Fly   710 VPLPAEAVELLETHSEFFKELAAIPRNQLLSEKWTALLASIKVKLIAALKDLQLFGLSTLSPEEL 774
            .|||...    .|..||..|
Mosquito   550 EPLPPHQ----NTTIEFVDE--------------------------------------------- 565

  Fly   775 VNRIWALGPRNCGTNILLNLSDYEQPDFWSSHAKSDTDIRSKTDPRKDFNSSLVNGFQITSVAGP 839
                      ..|||:                             .|.|...:..||:..:..|.
Mosquito   566 ----------TMGTNV-----------------------------PKQFIPGIEKGFRQMAEKGL 591

  Fly   840 LCEEPMQGVCFAVLEWSIQSEGEDLNSRGPFSGQVLTAAKEVCRQAFQNQPQRLVTPMYSCNIVV 904
            |....:.|:.|     .:|.....:......:  .:.||:...:..|:|...:::.|:....:..
Mosquito   592 LSGHKLSGIKF-----RLQDGAHHIVDSSELA--FMLAAQGAIKSVFENGSWQILEPIMMVEVTA 649

  Fly   905 NAEMLGKMYAVIGRRHGKILSGDLTQGS-GNFAVTCLLPVIESFNFAQEMRKQTSGLACPQLMFS 968
            ..|..|.:...:.:||| |::|  |:|: |.|.|...:|:.:.|.:|.|:|..|.|.....:.:|
Mosquito   650 PEEFQGTVIGQLNKRHG-IITG--TEGAEGWFTVYAEVPLNDMFGYAGELRSSTQGKGEFSMEYS 711

  Fly   969 HWEVIDIDPFWLPTTEEELMHFGEKADSANRAKVYMDSVRRRKGLFVDEQ 1018
            .:...      :|..:|:|.|            .|..|    :||.||::
Mosquito   712 RYSPC------MPEVQEKLCH------------EYQVS----QGLVVDKK 739

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33158	NP_788515.1	PRK13351	15..1016	CDD:481252	201/1020 (20%)
mEFG1	XP_318822.5	None