Protein Alignment CG33158 and Efl1

DIOPT Version :10

• Sequence 1: NP_788515.1
• Gene: CG33158 / 39834
• FlyBaseID: FBgn0053158
• Length: 1033
• Species: Drosophila melanogaster
• Sequence 2: NP_780526.2
• Gene: Efl1 / 101592
• MGIID: 2141969
• Length: 1127
• Species: Mus musculus
• Alignment Length: 1152
• Identity: 519/1152 - (45%)
• Similarity: 722/1152 - (62%)
• Gaps: 147/1152 - (12%)

  Fly     3 VVEGSD-LVLLQRRRQQVRNICILAHVDHGKTTLADSLVASNGIISQRMAGKLRYLDNRSDEQER 66
            |:.|.| ::.||:....:||||:|||||||||||||.|::||||||.|:||||||:|:|.|||.|
Mouse     2 VLSGVDKMIRLQKNTANIRNICVLAHVDHGKTTLADCLISSNGIISSRLAGKLRYMDSREDEQVR 66

  Fly    67 GITMKSSSISLYYQEAEEMAGNPDYLINLIDSPGHVDFSSEVSTAVRLCDGAIVVVDVVEGVGPQ 131
            |||||||:|||:|.|     |:.:|||||||||||||||||||||||:|||.|:|||.||||.||
Mouse    67 GITMKSSAISLHYAE-----GHEEYLINLIDSPGHVDFSSEVSTAVRICDGCIIVVDAVEGVCPQ 126

  Fly   132 TRACLRQIYEEQLKPVLVLNKLDRLILEKQMDPLDAYFHLCQVLEQVNAVLGSIFASDILAKEDI 196
            |:|.|||.:.|.::||||:||:||||:|.:..|.:||.||..:|||:||:.|::|.|.:|  |:.
Mouse   127 TQAVLRQAWLENIRPVLVINKIDRLIVELKFTPQEAYSHLKNILEQINALTGTLFTSKVL--EER 189

  Fly   197 TKKD----------------NYESALEEVDDSELYFSPSSGNVIFCSAYDGWAFSVRDFAAMYAK 245
            .:::                ::.:.||:||||:|||||..|||:|.||.|||.|.:..||.:|::
Mouse   190 AERETESQAKPHSEQGEQVYDWSAGLEDVDDSQLYFSPEQGNVVFTSAIDGWGFGIEHFARIYSQ 254

  Fly   246 RLEMSRKDLENVLWGDFYYNSKKKEALPGAQEKAKKPMFVQFVLENIWSLYDIIAIRKDKDKLPG 310
            ::.:.::.|...||||:|.|.|.|:.:...|.|.|||:|||.:|||||||||.: ::|||:|:..
Mouse   255 KIGIKKEVLLKTLWGDYYINMKAKKIMKVDQAKGKKPLFVQLILENIWSLYDAV-LKKDKEKIDK 318

  Fly   311 IAEKLGLKLATRDLRLTDPKLQIKAVLGQWLPIDKSVLHMVIQHVPPPHKISDERAQRLLYPANV 375
            |...||||:..|:.|.:|||:||.|:..|||||..:||.||...:|.|..::.||.::||...:.
Mouse   319 IVTSLGLKIGAREARHSDPKVQINAICSQWLPISHAVLAMVCHKLPSPLDMTSERVEKLLCTGSQ 383

  Fly   376 DLSSLPPETLELKESFTSCDA-NSSNVIAFVSKMTPVHITHLPQNRPKRLTDQEVQQRRDEVRRR 439
            ...||||||..||.:|..|.: :::.||.|||||..|.:..||||:|:.||.:|:.|||:..|:|
Mouse   384 TFESLPPETQALKAAFMKCGSEDTAPVIIFVSKMFAVDVKALPQNKPRPLTQEEMAQRRERARQR 448

  Fly   440 IEERKQQSEQAELEKISQGVEQ----LSTQVVGPEKEESKPEEAD-------------QNEFVFI 487
            ..|:...::    .:.|||..|    |.|   .|.::|.:.:|.|             .::..||
Mouse   449 HAEKLAAAQ----GQTSQGPTQDGGALET---SPHEDEPRGDEPDVASVSRQPVSQEESSQEAFI 506

  Fly   488 AFARVFSGTLKRGMELFNLSPKHDPRQPTHRKE----------GEAPYASRVTIGDLYMFMGGEL 542
            ||||||||..:||.::|.|.||:.|.....|..          ...|:.:..|:.:||:.||.||
Mouse   507 AFARVFSGIARRGKKIFVLGPKYSPVDFLQRVPLGFSAPLEDLPPVPHMACCTLENLYLLMGREL 571

  Fly   543 QLLDEVPAGNIVGIGGLESHIVKTATLSSSLDCTSFSELSVMATPILRVAIEPVQPQDMPKLVKG 607
            :.|:|||.||::|||||:..::|:|||.|...|..|..|:..||||:|||:||..|.:||:||||
Mouse   572 EDLEEVPPGNVLGIGGLQDFVLKSATLCSLPSCPPFIPLNFEATPIVRVAVEPKHPSEMPQLVKG 636

  Fly   608 LKLLNQADACVQVSVAPTGEHVITTLGEVHVEKCVHDLEQSYAKIKVNVSKPIVSFRETIVPAAT 672
            :|||||||.||||.:..|||||:.|.||||:::|:.||.:.:|||.::||:||:.|||||.....
Mouse   637 MKLLNQADPCVQVLIQETGEHVLVTAGEVHLQRCLDDLRERFAKIHISVSEPIIPFRETITKPPK 701

  Fly   673 VDMVNEAI---VKTA-------EDKDVSKKIAVQQ-------TLNKLGTLKVIAVPLPAEAVELL 720
            ||||||.|   .|.|       |...:.:.|.|..       |.|||.||.|.|:|||.|...:|
Mouse   702 VDMVNEEIGRQQKVAVIHQTKEEQSKIPEGIHVDSDGLITIPTPNKLATLSVRAIPLPEEVTRIL 766

  Fly   721 ETHSEFFKELAAIP------RN-QLLSEKWTALLASIKVKLIAALKDLQLFGLSTLSPEELVNRI 778
            |.:|:..:.:..:.      || |.:.:|....:...|.||     :..|.|...   ...|::|
Mouse   767 EENSDLIRSMELLTSSLNEGRNTQAIHQKTQEKIWEFKGKL-----EKHLTGRKW---RNTVDQI 823

  Fly   779 WALGPRNCGTNILLNLSDYEQPDFWSSHAKSDTDIRSKTDPRKDFNSSLVNGFQITSVAGPLCEE 843
            |:.|||.||.|||::.|:..|...||..|..::...|:.   :||.:|:|:|||:.:::||:|||
Mouse   824 WSFGPRKCGPNILVSRSEDFQNSVWSGPAGRESKEASRF---RDFGNSIVSGFQLATLSGPMCEE 885

  Fly   844 PMQGVCFAVLEWSI-----------QSEGE-----------------DLNSR------------- 867
            |:.||||.:.:|.:           |.:|:                 |.|..
Mouse   886 PLMGVCFVLEKWELNKCAEQGASDKQHQGQCDLAGEGQGGGKTCHVGDENQEQQDVCSEPFEETS 950

  Fly   868 -----------GPFSGQVLTAAKEVCRQAFQNQPQRLVTPMYSCNIVVNAEMLGKMYAVIGRRHG 921
                       ||||||::...||.||.|.|.:||||:..||:|:|:..:::||::|||:.:|.|
Mouse   951 QKGDSPVIDCYGPFSGQLIATMKEACRYALQVKPQRLMAAMYTCDIMATSDVLGRVYAVLSKREG 1015

  Fly   922 KILSGDLTQGSGNFAVTCLLPVIESFNFAQEMRKQTSGLACPQLMFSHWEVIDIDPFWLPTTEEE 986
            ::|..::.:|:..|.:..:|||.|||.||.|:||:|||||.|||:|||||||..||||:||||||
Mouse  1016 RVLQEEMKEGTDMFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEVIPSDPFWVPTTEEE 1080

  Fly   987 LMHFGEKADSANRAKVYMDSVRRRKGLFVDEQVVEHAEKQRTLSKNK 1033
            .:||||||||.|:|:.||::||:||||:|:|::||||||||||||||
Mouse  1081 YLHFGEKADSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSKNK 1127

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33158	NP_788515.1	PRK13351	15..1016	CDD:481252	498/1120 (44%)
Efl1	NP_780526.2	PRK13351	1..1110	CDD:481252	503/1133 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	429..496		20/73 (27%)