Protein Alignment CG33158 and efl1

DIOPT Version :9

• Sequence 1: NP_788515.1
• Gene: CG33158 / 39834
• FlyBaseID: FBgn0053158
• Length: 1033
• Species: Drosophila melanogaster
• Sequence 2: XP_002940146.3
• Gene: efl1 / 100492738
• XenbaseID: XB-GENE-5894854
• Length: 1136
• Species: Xenopus tropicalis
• Alignment Length: 1166
• Identity: 535/1166 - (45%)
• Similarity: 735/1166 - (63%)
• Gaps: 163/1166 - (13%)

  Fly     1 MPVVEGSDLVLLQRRRQQVRNICILAHVDHGKTTLADSLVASNGIISQRMAGKLRYLDNRSDEQE 65
            |.:|....:|.||:|...:||||||||||||||||||.|::||||||.|:||||||||:|.|||.
 Frog     1 MGLVSLEKIVTLQKRAANIRNICILAHVDHGKTTLADCLISSNGIISNRLAGKLRYLDSREDEQI 65

  Fly    66 RGITMKSSSISLYYQEAEEMAGNPDYLINLIDSPGHVDFSSEVSTAVRLCDGAIVVVDVVEGVGP 130
            ||||||||:|||:|::.||     :|||||||||||||||||||||||||||.|:|||.||||.|
 Frog    66 RGITMKSSAISLHYKDDEE-----EYLINLIDSPGHVDFSSEVSTAVRLCDGCIIVVDSVEGVCP 125

  Fly   131 QTRACLRQIYEEQLKPVLVLNKLDRLILEKQMDPLDAYFHLCQVLEQVNAVLGSIFASDILAKED 195
            ||:|.|||.:.|.::||||:||:||||.|.::..|:||.||.::|||||||.||:|.|.:|  |:
 Frog   126 QTQAVLRQAWLENIRPVLVINKIDRLITELKLSCLEAYSHLQKILEQVNAVTGSLFTSKVL--EE 188

  Fly   196 ITKKD----------------NYESALEEVDDSELYFSPSSGNVIFCSAYDGWAFSVRDFAAMYA 244
            ..:||                ::.:.|||.|||.|||||..|||:|.||.|||.|::..||.:|:
 Frog   189 RAEKDMASDVPSETVDGDQVYDWSAGLEETDDSHLYFSPDQGNVVFASAIDGWGFTIDHFAQLYS 253

  Fly   245 KRLEMSRKDLENVLWGDFYYNSKKKEALPGAQEKAKKPMFVQFVLENIWSLYDIIAIRKDKDKLP 309
            :::.:....|...||||:|.|:|.|:.:.|||.|.|||:|||.:|:|:|||||.: |:::|:|:.
 Frog   254 QKVGIKAAVLLKTLWGDYYLNTKAKKIMKGAQSKGKKPLFVQLILDNLWSLYDAV-IKREKEKID 317

  Fly   310 GIAEKLGLKLATRDLRLTDPKLQIKAVLGQWLPIDKSVLHMVIQHVPPPHKISDERAQRLLYPAN 374
            .|...||||::.|:.|.:|||:.:.|:..|||||.::||.||.:.:|.|..|..||.::||...:
 Frog   318 KIVLSLGLKISPRESRHSDPKVHVNAICSQWLPISQAVLSMVCRKLPSPLDIPAERVEKLLCVGS 382

  Fly   375 VDLSSLPPETLELKESFTSCDAN-SSNVIAFVSKMTPVHITHLPQNRPKRLTDQEVQQRRDEVRR 438
            ....|||.||.:|||:|..|.:: ::.||.|||||..|....||||:.:.||.:|:..||:..|:
 Frog   383 RRFDSLPQETQQLKETFLKCRSDETAPVIIFVSKMFAVDAKALPQNKQRPLTQEEIALRRELARQ 447

  Fly   439 RIEERKQ-QSEQAELEKI--------------SQGVEQLS---TQVVGPEKEESKPEEADQNEFV 485
            |..|:.. ..||...|::              ::|.:|.|   .:||.|||:|:      :|:..
 Frog   448 RHAEKMAINQEQLPAEQVPSSNECEMPANKENTKGDKQTSHRDPEVVKPEKQEA------ENKSY 506

  Fly   486 FIAFARVFSGTLKRGMELFNLSPKHDPRQ----------PTHRKEGEAPYASRVTIGDLYMFMGG 540
            ||||||||||.::||.::|.|.||:||.:          |.....| .|:.:..::.:||:.||.
 Frog   507 FIAFARVFSGIVRRGQKIFVLGPKYDPAETLLKLPLNCTPACDLPG-IPHMACCSLDNLYLLMGR 570

  Fly   541 ELQLLDEVPAGNIVGIGGLESHIVKTATLSSSLDCTSFSELSVMATPILRVAIEPVQPQDMPKLV 605
            ||:.|:|||.||::||||||..::|:||||:|..|..|..|:..||||:|||:||..|.:||:||
 Frog   571 ELENLEEVPVGNVLGIGGLEEFVLKSATLSTSPACPPFIPLNFEATPIVRVAVEPKHPSEMPQLV 635

  Fly   606 KGLKLLNQADACVQVSVAPTGEHVITTLGEVHVEKCVHDLEQSYAKIKVNVSKPIVSFRETIVPA 670
            ||:|||||||.||:|.:..|||||:.|.||||:::|:.||.:.:|||:|:.|.||:.|||||:..
 Frog   636 KGMKLLNQADPCVEVLIQETGEHVLITAGEVHLQRCLDDLRERFAKIQVSSSAPIIPFRETIIRP 700

  Fly   671 ATVDMVNEAIVKTAEDKDVSKKIAV------QQ------------------TLNKLGTLKVIAVP 711
            ..||||||.|.|       .:||||      :|                  |.|||.||.|.|:|
 Frog   701 PKVDMVNEEIGK-------QQKIAVIHQVKEEQSKCPEGVQVDPDGLVTLTTPNKLATLSVRAMP 758

  Fly   712 LPAEAVELLETHSEFFKELAAIPRNQLLSE-KWTALLASIKVKLIAALK-DLQLFGLSTLSPEEL 774
            ||.|..:|||.:|:..:.:..|  |..|:| .:|.......::.|.|.| :||.. |........
 Frog   759 LPEEVTQLLEKNSDLIRTMEQI--NMALNEGSYTIHFNESAIERITAFKSNLQQL-LQGRRWRNA 820

  Fly   775 VNRIWALGPRNCGTNILLN-LSDYEQPDFWSSHAKSDTDIRSKTDPRKDFNSSLVNGFQITSVAG 838
            |::||:.|||..|.||||| :..|::|..|....||   ||.  ...::|::|:|:|||:.::||
 Frog   821 VDQIWSFGPRRYGPNILLNRIEGYDRPSVWQCLEKS---IRE--GKYRNFDNSIVSGFQLATLAG 880

  Fly   839 PLCEEPMQGVCFAVLEWSIQ---------SEGEDLNSR--------------------------- 867
            |:||||:.||||.|.:..:.         |:..::::|
 Frog   881 PMCEEPLMGVCFIVEKLDLSRPLLAKDSASQDSEVDTRTEPEHSETGTTGTTGALINNISTSATE 945

  Fly   868 -------------------------GPFSGQVLTAAKEVCRQAFQNQPQRLVTPMYSCNIVVNAE 907
                                     ||||||::...||.||.|||.:||||:..||:|.|:..||
 Frog   946 ETELIPENGARPFSKRKGDLLTDCYGPFSGQLIATMKEACRYAFQVKPQRLMAAMYTCEIMATAE 1010

  Fly   908 MLGKMYAVIGRRHGKILSGDLTQGSGNFAVTCLLPVIESFNFAQEMRKQTSGLACPQLMFSHWEV 972
            :||::|.|:.:|.|::|..::.:|:..|.:..:|||.|||.||.|:||:|||||.|||:||||||
 Frog  1011 VLGRVYGVLSKREGRVLLEEMKEGTDMFIIKAVLPVAESFGFADEIRKRTSGLASPQLVFSHWEV 1075

  Fly   973 IDIDPFWLPTTEEELMHFGEKADSANRAKVYMDSVRRRKGLFVDEQVVEHAEKQRTLSKNK 1033
            |..||||:||||||.:||||||||.|:|:.||:|||:||||:|:|::||||||||||.|||
 Frog  1076 ISSDPFWVPTTEEEYLHFGEKADSENQARKYMNSVRKRKGLYVEEKIVEHAEKQRTLGKNK 1136

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG33158	NP_788515.1	PTZ00416	15..1016	CDD:240409	515/1133 (45%)
		EF2	20..249	CDD:206672	150/244 (61%)
		EF2_II	485..572	CDD:293913	44/96 (46%)
		EF2_snRNP_III	587..658	CDD:293918	41/70 (59%)
		aeEF2_snRNP_like_IV	658..899	CDD:238839	104/328 (32%)
		eEF2_snRNP_like_C	896..974	CDD:239763	40/77 (52%)
efl1	XP_002940146.3	FusA	5..1119	CDD:357662	518/1143 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	342	1.000	Domainoid score	I1071
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11599
Inparanoid	1	1.050	929	1.000	Inparanoid score	I350
OMA	1	1.010	-	-		QHG53952
OrthoDB	1	1.010	-	-		D140796at2759
OrthoFinder	1	1.000	-	-		FOG0004608
OrthoInspector	1	1.000	-	-		oto104098
Panther	1	1.100	-	-	LDO	PTHR42908
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3227
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.080