Protein Alignment TyrRS and ARC1

DIOPT Version :10

• Sequence 1: NP_648895.1
• Gene: TyrRS / 39829
• FlyBaseID: FBgn0027080
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_011410.1
• Gene: ARC1 / 852773
• SGDID: S000003073
• Length: 376
• Species: Saccharomyces cerevisiae
• Alignment Length: 454
• Identity: 130/454 - (28%)
• Similarity: 187/454 - (41%)
• Gaps: 141/454 - (31%)

  Fly   135 LSSVVTQHDA-----------KKAGAEVVKQVEYPLLSGLLYPGLQAL----------------- 171
            :|.:||:.::           |:..|:.. |.|..|.||.:.|.|..|
Yeast     1 MSDLVTKFESLIISKYPVSFTKEQSAQAA-QWESVLKSGQIQPHLDQLNLVLRDNTFIVSTLYPT 64

  Fly   172 --DEEYLKV------DAQFGGVDQRKIFTFSEKYLPQLGYEKRIHFMNPMVPGLAGGKMSSSEED 228
              |....:|      |......|.:..:|.....|..:.|.:.:.            ::||::
Yeast    65 STDVHVFEVALPLIKDLVASSKDVKSTYTTYRHILRWIDYMQNLL------------EVSSTD-- 115

  Fly   229 SKIDL---LDSPANVKKKLKKAFCEPGNIADNGLLSFVKHVLFSLFKEGEGFEVNREAEHGGDVT 290
             |:::   ||.|..|.:|.|||  ..|..||            :..|..|  :|:::|
Yeast   116 -KLEINHDLDLPHEVIEKKKKA--PAGGAAD------------AAAKADE--DVSKKA------- 156

  Fly   291 FLKYEDLEKYYAEDKLHPGDLKATVEKYINRLLDPIRKAFENPELQKLSAAAYPPPAKVKAGAAP 355
              |.:|          ||                  |...:...|:||.     ..||.|..|..
Yeast   157 --KKQD----------HP------------------RGKPDEETLKKLR-----EEAKAKKAAKK 186

  Fly   356 AAGA-----------DEDAPHRLDIRVGKVVEVARHPDADTLYVLKIDLAEAQ-PRTIISGLVKF 408
            ||.|           ::..|..:|.|||.:.:..:|||||:|||..||:.:.: |||:.|||||.
Yeast   187 AANAKQQQEQQNKAPEKPKPSAIDFRVGFIQKAIKHPDADSLYVSTIDVGDEEGPRTVCSGLVKH 251

  Fly   409 VTEEELNQRLVAVLCNLKPSKMRGILSEGMVLCTSNADHT-VVEPIVLPATATAGSRLSFEGFSG 472
            ...:.:.:|.|.|:|||||..||||.|..||||.||.|.. .|||   |..:.||.::.||||..
Yeast   252 FPLDAMQERYVVVVCNLKPVNMRGIKSTAMVLCGSNDDKVEFVEP---PKDSKAGDKVFFEGFGD 313

  Fly   473 -TPDEQLNPKKKVWEKLSADFKTNSDGL-AVWKD--------NFLLTPEGEKLS-SKLANCSIK 525
             .|.:|||||||:||.|...|.|| ||| .::||        ..|...:||... :.:||..::
Yeast   314 EAPMKQLNPKKKIWEHLQPHFTTN-DGLEVIFKDEEEKDHPVRKLTNAKGESFKVASIANAQVR 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TyrRS	NP_648895.1	nt_trans	8..334	CDD:469580	43/237 (18%)
		PLN02610	<366..525	CDD:215329	76/171 (44%)
ARC1	NP_011410.1	GST_C_Arc1p_N_like	22..119	CDD:198337	20/112 (18%)
		PLN02610	<193..376	CDD:215329	77/186 (41%)