DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TyrRS and AT1G28350

DIOPT Version :9

Sequence 1:	NP_648895.1	Gene:	TyrRS / 39829	FlyBaseID:	FBgn0027080	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_001319097.1	Gene:	AT1G28350 / 839731	AraportID:	AT1G28350	Length:	748	Species:	Arabidopsis thaliana

Alignment Length:	551	Identity:	140/551 - (25%)
Similarity:	242/551 - (43%)	Gaps:	105/551 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 EKKALITRNL-QETLGDDKLTKILAERDLKI-YWGTATTGKPHVAY-FVPMSKIADFLKAGCEVT 69
            ||:..:.|:: ::.:.||:|..:||::...: |.|...:|:.|:|. .:.:..:.....|||.|.
plant    26 EKRYNVVRSVGEQCIHDDELKDLLAKKAAPVCYDGFEPSGRMHIAQGLMKIMNVNKLTSAGCRVK 90

  Fly    70 ILFADLHAYLDNMKAPWSLLELRT--KYYEQVIKAMLSSIGVPLEKLKFVKGSDYQLSK--EY-- 128
            |..||..||::| |....|.::|.  :|::::.:|    .|:..|.::|:..||...:|  ||
plant    91 IWIADWFAYMNN-KLGGDLKKIRVVGEYFKEIFQA----AGMNSENVEFLWSSDEINAKGDEYWP 150

  Fly   129 -TLDVYKLSSVVTQHDAKKAGAEVVKQVEYPLLSG--LLYPGLQALDEEYLKVDAQFGGVDQRKI 190
             .:|:...:|:.    ..|....::...|...||.  :||..:|..|..:|:.|....|:||:.:
plant   151 LVMDIACRNSLA----QIKRCMPIMGLSENEELSAAHILYVCMQCADTFFLEADICQLGMDQQTV 211

  Fly   191 FTFSEKYLPQLGYE-KRIHFMNPMVPGLAGG--KMSSSEEDSKIDLLDSPANVKKKLKKAFCEPG 252
            ...:..|...:..| |.:...:.|:|||..|  |||.|:..|.|.:.|..|.|..|:|||:|.|.
plant   212 NLLARDYCDVVKRENKPVILSHHMLPGLQQGQKKMSKSDPSSAIFMEDEEAEVNVKIKKAYCPPD 276

  Fly   253 NIADNGLLSFVKHVLFSLFKEGEGFEVNREAEHGGDVTFLKYEDLEKYYAEDKLHPGDLKATVEK 317
            .:..|..|.:|||::...|.|   |.|.|:.::||:.||..:||:...|...:|||.|||..:.|
plant   277 IVEGNPCLEYVKHIILPWFSE---FTVERDEKYGGNRTFKSFEDITTDYESGQLHPKDLKDALSK 338

  Fly   318 YINRLLDPIRKAFE-NPELQKL--SAAAYPPPAKVKAGAAPAAGADEDAPHRLDIRV-----GKV 374
            .:|::|.|:|..|: |...:.|  ....|    ||......|:...|:     |:.:     ...
plant   339 ALNKILQPVRDHFKTNSRAKNLLKQVKGY----KVTRVIPTASSTKEE-----DLSINTSASSSA 394

  Fly   375 VEVARHPDADTLYVLKIDLAEAQPRTIISGLVKFVTEEELNQRLV---AVLC--NLKPSKMRGIL 434
            ..:....:|:..|.:...:.|           :.:.|:||...|.   |.:|  ..:||. |..:
plant   395 AGLQMSEEAEMKYKIVRSIGE-----------ECIQEDELKNLLAKKPAPICYDGFEPSG-RMHI 447

  Fly   435 SEGMVLCTSNADHTVVEPIVLPATATAGSRLSF---EGFSGTPDEQLNPK--------------- 481
            ::|::..|:           :....:||.::..   :.|:     |||.|
plant   448 AQGVMKVTN-----------VNKLTSAGCQVKIWIADWFA-----QLNNKLGGDLERIRVVGEYF 496

  Fly   482 KKVW----------EKLSADFKTNSDGLAVW 502
            |::|          |.|.|..:.|..|...|
plant   497 KEIWQAGGMNNDKVEFLWASDEINGKGSKYW 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TyrRS	NP_648895.1	nt_trans	8..334	CDD:294020	104/341 (30%)
		tyrS	12..332	CDD:272976	101/335 (30%)
		tRNA_bind_EMAP-II_like	364..466	CDD:239198	17/111 (15%)
AT1G28350	NP_001319097.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	116	1.000	Domainoid score	I1969
eggNOG	1	0.900	-	-		E1_COG0162
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	131	1.000	Inparanoid score	I1874
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D852081at2759
OrthoFinder	1	1.000	-	-		FOG0000771
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101224
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2335
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.770