DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TyrRS and mars2

DIOPT Version :9

Sequence 1:	NP_648895.1	Gene:	TyrRS / 39829	FlyBaseID:	FBgn0027080	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	XP_021329980.1	Gene:	mars2 / 566565	ZFINID:	ZDB-GENE-111201-1	Length:	595	Species:	Danio rerio

Alignment Length:	232	Identity:	49/232 - (21%)
Similarity:	83/232 - (35%)	Gaps:	71/232 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 ITPAEKKALITRNLQETLGDDKLTKILAERD-LKIYWGTATTGKPHVAYFVPMSKIADFLKAGCE 67
            |.|.:.:.|:.:.|:    ||.:..:...|. .::.||....|.|....:|.:..:.::|
Zfish   232 IQPVKFQHLVLQWLE----DDDIPDLSVSRQKSRLQWGIPVPGDPEQTIYVWLDALVNYL----- 287

  Fly    68 VTILFADLHAYLDNMKAPWS---------LLELRTKYYEQVI---------------------KA 102
             |::     .|..|....||         :|:....|:...:                     |.
Zfish   288 -TVV-----GYPQNHSKWWSVVHHVVGKDILKFHAIYWPAFLLAAGLALPQKIYVHSHWTVEGKK 346

  Fly   103 MLSSIG---VPLEKL-KF-VKGSDYQLSK----EYTLDVY--KLSSVVTQHDAKKAGAEV----- 151
            |..|||   .|||.: || |.|..|.|.:    :...|.|  |:..:.....|...|..:
Zfish   347 MSKSIGNVINPLESIEKFTVDGLRYFLLRQGVPDSDCDYYDDKVMKMCNSELADALGGLLNRCTA 411

  Fly   152 ----VKQVEYPLLSGLLYPGL----QALDEEYLKVDA 180
                :.|| ||..|...:|.:    :|:.|:|..::|
Zfish   412 PSLNLTQV-YPRFSNSCFPAVGLSGKAVSEDYRMIEA 447

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TyrRS	NP_648895.1	nt_trans	8..334	CDD:294020	47/228 (21%)
		tyrS	12..332	CDD:272976	47/224 (21%)
		tRNA_bind_EMAP-II_like	364..466	CDD:239198
mars2	XP_021329980.1	PRK12267	45..594	CDD:330948	49/232 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0143
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900