Protein Alignment TyrRS and MetRS-m

DIOPT Version :9

• Sequence 1: NP_648895.1
• Gene: TyrRS / 39829
• FlyBaseID: FBgn0027080
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_001262564.1
• Gene: MetRS-m / 41733
• FlyBaseID: FBgn0027083
• Length: 582
• Species: Drosophila melanogaster
• Alignment Length: 466
• Identity: 80/466 - (17%)
• Similarity: 145/466 - (31%)
• Gaps: 165/466 - (35%)

  Fly    47 PHVAYFVPMSKIADFLKAGCEVTILFADLHAYLDNMKAPWSLLELRTKYYEQ--VIKAMLSSIGV 109
            ||:.:.               .:.:.||.|.....::.|...:.|.|...|.  .|:...|..||
  Fly    33 PHIGHL---------------YSAVIADAHCRYQRLRYPEQDVRLCTGTDEHGTKIQQAASLHGV 82

  Fly   110 PLEKLKFVKGSDY--QLSKEYTLDVYKLSSV-------VTQHDAKKAGAEVVKQVE-----YPLL 160
            |:.|        |  .:|:.|. :|::.:|:       .|:...|:|.|...:.:.     |
  Fly    83 PVAK--------YCDDISQRYR-EVFRSASIQQDDFIRTTEDRHKRAVANFWRTLHTRGHIY--- 135

  Fly   161 SGLLYPGLQALDEEYLKVDAQFGGVDQRKIFTFSEKYLPQLGYEKRIHFMNPMVPGLAGGKMSSS 225
             ...|.|...:.:|....|:|. .:|:.....:|.:....:.:.:..::|         .::|..
  Fly   136 -SAAYSGWYCVSDETFLTDSQL-RLDEATGTRYSLESGHPVEWTEETNYM---------FRLSQF 189

  Fly   226 EED----SKIDLLDSPANVKKKLKKAFCEPGNIADNGLLSFVKHVLFSLFKEGEGFEVNREAEHG 286
            ::|    .|.:....||..:|.|.....||
  Fly   190 QDDVRHWVKTEARVRPAKFEKILLDTLSEP----------------------------------- 219

  Fly   287 GDVTFLKYEDLEKYYAEDKLH-----PGDLKATVEKYINRLLDPIRKAFENPELQKLSAAAYP-- 344
                   ..|:......:::|     |.|...||..:::.|::            .||:..||
  Fly   220 -------LPDVSVSRPSNRVHWAIPVPDDDSQTVYVWLDALVN------------YLSSVGYPDE 265

  Fly   345 ------PPAKVKAG-----------AAPAAGADEDAPHRLDIRV-----GKVVEVARHPDADTLY 387
                  |||:...|           .|....|..:.|.:|.:..     |:.:..::|...|.|
  Fly   266 KFSAHWPPAQQVIGKDILKFHGIYWTAFLLAAGLEPPGQLYVHSHWTVDGQKMSKSKHNVVDPL- 329

  Fly   388 VLKIDLAEAQPRTIISGLVKFVTEEE----------------LNQRLVAVLCNLKPSKMRGILSE 436
                   :|..:..:.||..|:..|.                ||..|...|.||........|:.
  Fly   330 -------QAAQQYTMEGLRYFLLREGVAHSDGNYSHVKAQRILNSELADTLGNLLSRASAKSLNP 387

  Fly   437 GMVLCTSNADH 447
            |.:..:.:|:|
  Fly   388 GQIYPSPSAEH 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TyrRS	NP_648895.1	nt_trans	8..334	CDD:294020	49/311 (16%)
		tyrS	12..332	CDD:272976	49/309 (16%)
		tRNA_bind_EMAP-II_like	364..466	CDD:239198	21/105 (20%)
MetRS-m	NP_001262564.1	MetRS_core	20..356	CDD:173907	70/422 (17%)
		PRK11893	21..553	CDD:237012	80/466 (17%)
		Anticodon_Ia_like	365..503	CDD:299868	10/34 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0143
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900