Protein Alignment TyrRS and Yars1

DIOPT Version :10

• Sequence 1: NP_648895.1
• Gene: TyrRS / 39829
• FlyBaseID: FBgn0027080
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_001020867.2
• Gene: Yars1 / 313047
• RGDID: 1307616
• Length: 564
• Species: Rattus norvegicus
• Alignment Length: 513
• Identity: 354/513 - (69%)
• Similarity: 416/513 - (81%)
• Gaps: 8/513 - (1%)

  Fly     5 TPAEKKALITRNLQETLGDDKLTKILAERDLKIYWGTATTGKPHVAYFVPMSKIADFLKAGCEVT 69
            :|.||..||||||||.||::||.:||.||:||:||||||||||||||||||||||||||||||||
  Rat    42 SPEEKLHLITRNLQEVLGEEKLKEILKERELKVYWGTATTGKPHVAYFVPMSKIADFLKAGCEVT 106

  Fly    70 ILFADLHAYLDNMKAPWSLLELRTKYYEQVIKAMLSSIGVPLEKLKFVKGSDYQLSKEYTLDVYK 134
            |||||||||||||||||.||||||.|||.||||||.|||||||||||.||:|||||||||||||:
  Rat   107 ILFADLHAYLDNMKAPWELLELRTSYYENVIKAMLESIGVPLEKLKFTKGTDYQLSKEYTLDVYR 171

  Fly   135 LSSVVTQHDAKKAGAEVVKQVEYPLLSGLLYPGLQALDEEYLKVDAQFGGVDQRKIFTFSEKYLP 199
            |||:||||||||||||||||||:|||||||||||||||||||||||||||:||||||||:|||||
  Rat   172 LSSLVTQHDAKKAGAEVVKQVEHPLLSGLLYPGLQALDEEYLKVDAQFGGIDQRKIFTFAEKYLP 236

  Fly   200 QLGYEKRIHFMNPMVPGLAGGKMSSSEEDSKIDLLDSPANVKKKLKKAFCEPGNIADNGLLSFVK 264
            .|||.||:|.||||||||.|.|||||||:|||||||...:||||||||||||||:.:||:|||||
  Rat   237 TLGYSKRVHLMNPMVPGLTGSKMSSSEEESKIDLLDRKEDVKKKLKKAFCEPGNVENNGVLSFVK 301

  Fly   265 HVLFSLFKEGEGFEVNREAEHGGDVTFLKYEDLEKYYAEDKLHPGDLKATVEKYINRLLDPIRKA 329
            ||||.|..|   |.:.|:.:.||:.|:..|::|||.:|.:.:||||||.:||..:|:||||||:.
  Rat   302 HVLFPLKSE---FVILRDEKWGGNKTYTIYQELEKDFAAEVVHPGDLKNSVEVALNKLLDPIREK 363

  Fly   330 FENPELQKLSAAAYPPPAKVK---AGAAPAAGADEDAPHRLDIRVGKVVEVARHPDADTLYVLKI 391
            |..|.|:||::||||.|:|.|   .|.|.::..:|..|.||||||||::.|.:|||||:|||.||
  Rat   364 FNTPALKKLASAAYPDPSKQKPTAKGPAKSSEPEEIIPSRLDIRVGKILSVEKHPDADSLYVEKI 428

  Fly   392 DLAEAQPRTIISGLVKFVTEEELNQRLVAVLCNLKPSKMRGILSEGMVLCTS-NADHTVVEPIVL 455
            |:.||:|||::||||:||.:|||..|||.|||||||.||||:.|:||:||.| ......|||:..
  Rat   429 DVGEAEPRTVVSGLVQFVPKEELQDRLVVVLCNLKPQKMRGVDSQGMLLCASVEGVSRQVEPLDP 493

  Fly   456 PATATAGSRLSFEGF-SGTPDEQLNPKKKVWEKLSADFKTNSDGLAVWKDNFLLTPEG 512
            ||.:..|.|:..:|: .|.|||:|.|||||:|||.||||.:.|.:|.||....:|..|
  Rat   494 PAGSAPGERVFVQGYEKGQPDEELKPKKKVFEKLQADFKISDDCVAQWKQTNFMTKLG 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TyrRS	NP_648895.1	nt_trans	8..334	CDD:469580	253/325 (78%)
		PLN02610	<366..525	CDD:215329	85/149 (57%)
Yars1	NP_001020867.2	nt_trans	44..364	CDD:469580	252/322 (78%)
		PLN02610	<363..564	CDD:215329	101/189 (53%)