Protein Alignment TyrRS and Mars1

DIOPT Version :10

• Sequence 1: NP_648895.1
• Gene: TyrRS / 39829
• FlyBaseID: FBgn0027080
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: XP_006241513.1
• Gene: Mars1 / 299851
• RGDID: 1305321
• Length: 910
• Species: Rattus norvegicus
• Alignment Length: 535
• Identity: 104/535 - (19%)
• Similarity: 172/535 - (32%)
• Gaps: 178/535 - (33%)

  Fly    33 RDLKIYWGTATTGKPHVAYFVPMSKIAD-FLKAGCEVTILFADLHA-YLDNMKAPWSLLELRTKY 95
            ||||  |||.          ||:....| ......:.||.:..:.| |.|..:..|       |.
  Rat   499 RDLK--WGTP----------VPLEGFEDKVFYVWFDATIGYLSITANYTDQWERWW-------KN 544

  Fly    96 YEQV-IKAMLSSIGVPLEKLKFVKGSDYQLSKEYTLDVYKLSSVVTQHDAKKAGAEVVKQVEYPL 159
            .||| :...::...||...|                 |:..|::         |||    ..|.|
  Rat   545 PEQVDLYQFMAKDNVPFHGL-----------------VFPCSAL---------GAE----DNYTL 579

  Fly   160 LSGLLYPGLQALDEEYLKVD----------AQFGGVDQ-----RKIFTFSEKYLPQLGYEKRIHF 209
            :..|       :..|||..:          ..||.:.|     ..|:.|...|:...|.:....:
  Rat   580 VKNL-------IATEYLNYEDGKFSKSRGIGVFGDMAQDTGIPADIWRFYLLYIRPEGQDSAFSW 637

  Fly   210 MNPMVPGLAGGKMSSSEEDSKIDLLDSPANVKKK----LKKAF--CEPGNIADNGLLSFVKHVLF 268
            .:.::      |.:|       :||::..|...:    :.|.|  |.|..:..:.....|.||
  Rat   638 TDLLI------KNNS-------ELLNNLGNFINRAGMFVSKFFGGCVPEMVLTHDDRRLVAHV-- 687

  Fly   269 SLFKEGEGFEVNREAEHGGDVTFLKYEDLEKYYAEDKLHPGDLKATVEKYINRLLDPIRKAFENP 333
                   .:|:.|           .::.|||....|.|..   ..|:.::.|:.:.
  Rat   688 -------SWELQR-----------YHQLLEKVRIRDALRS---ILTISRHGNQYIQ--------- 722

  Fly   334 ELQKLSAAAYPPPAKVKAGAAPAAGADEDAPHRLDIRVGKVVEVAR---------HPDADTLYVL 389
                    ...|..::|        .||....|.....|..|.:|.         .|...:....
  Rat   723 --------VNEPWKRIK--------GDEMDRQRAGTVTGMAVNIAALLSVMLQPYMPTVSSTIQT 771

  Fly   390 KIDLAEAQPRTIISGLV-------KFVTEEELNQRLV-AVLCNLKPSKMRGILSEGMVLCTSNAD 446
            ::.|.||..|.:.:..:       :..|...|.|:|. ..:.||:.....|.|.|.:.|....:.
  Rat   772 QLQLPEAACRILATSFICTLPAGHRIGTVSPLFQKLENDQIENLRQRFGGGQLEESLELQAKGSP 836

  Fly   447 HTVVEPIVLPATATAGSRLSFEGFSGTPDE---------QLNPKKKVWEKLSADFKTNSD---GL 499
                :|.|:.|..||||    :......||         :|..:|....:::|:.....|   .|
  Rat   837 ----KPAVVEAVTTAGS----QDIQVLVDEVTKQGNIVRELKAQKADKNQVAAEVAKLLDLKKQL 893

  Fly   500 AVWKDNFLLTPEGEK 514
            |:.:...:.||:|:|
  Rat   894 ALAEGKPIETPKGKK 908

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TyrRS	NP_648895.1	nt_trans	8..334	CDD:469580	62/324 (19%)
		PLN02610	<366..525	CDD:215329	38/178 (21%)
Mars1	XP_006241513.1	GST_N_5	1..74	CDD:436537
		GST_C_MetRS_N	77..179	CDD:198340
		PLN02610	258..>839	CDD:215329	85/460 (18%)
		MetRS_RNA	855..899	CDD:238475	8/43 (19%)