Protein Alignment TyrRS and Yars2

DIOPT Version :9

• Sequence 1: NP_648895.1
• Gene: TyrRS / 39829
• FlyBaseID: FBgn0027080
• Length: 525
• Species: Drosophila melanogaster
• Sequence 2: NP_001009627.1
• Gene: Yars2 / 287924
• RGDID: 1311696
• Length: 471
• Species: Rattus norvegicus
• Alignment Length: 435
• Identity: 86/435 - (19%)
• Similarity: 147/435 - (33%)
• Gaps: 126/435 - (28%)

  Fly    37 IYWGTATTGKP-HVAYFVPMSKIADFLKAGCEVTILFADLHAYLDNMKAPWSLLELRTKYYE--- 97
            :|.|...||.. ||.:.:.:..:..|.:||..|..|.....|.|.:...       |||..|
  Rat    70 VYCGFDPTGDSLHVGHLLTLLGLFHFQRAGHNVIALVGGSTALLGDPSG-------RTKEREALS 127

  Fly    98 -QVIKAMLSSIGVPLEKLK------FVKGSDY----------QLSKEYTLDV-------YKLSSV 138
             :.::|...::...||.|.      |..|..:          ...|::.:|.       :::.::
  Rat   128 AECVRANARALQRGLETLAANHARLFADGRPWGTFTVLDNAAWFQKQHLMDFLATVGGHFRMGTL 192

  Fly   139 VTQHDAKKAGAEVVKQVEYPLLSGLLYPGLQALDEEYL----KVDAQFGGVDQRKIFTFSEKYLP 199
            :::...:..    :|..|...|:...|..|||.|..||    ....|.||.||........:::.
  Rat   193 LSRLSVQSR----LKSPEGMSLAEFFYQVLQAYDFYYLFRHYGCRVQLGGSDQLGNIMSGYEFIH 253

  Fly   200 QLGYEKRIHFMNPMVPGLAGGKMSSS---------EEDSKIDLL-----DSPANVKKKLKKAFCE 250
            :|..|.......|::....|.|:..|         |:.|..:|.     ....:|::.||
  Rat   254 KLTGEDVFGITVPLITSTTGAKLGKSAGNAVWLNREKTSPFELYQFFIRQQDDSVERYLK----- 313

  Fly   251 PGNIADNGLLSF-----VKHVLFSLFKEGEGFEVNREAEH--GGDVTFLKY--EDLEKYYAEDKL 306
                    |.:|     :.|::....||.|    .|.|:.  ..:||.|.:  |.|:
  Rat   314 --------LFTFLPLPEIDHIMQLHVKEPE----KRIAQKRLAAEVTKLVHGQEGLD-------- 358

  Fly   307 HPGDLKATVEKYINRLLDPIRKAFENPELQKL------SAAAYPPPAKV-----KAGAAPAAGAD 360
               ..|...:...:..::.: :...:.||::|      |.....|...|     ||.|.|
  Rat   359 ---SAKRCTQALYHSSIEAL-EVMSDQELKELFKEASFSELVLDPGTSVIDTCRKANAIP----- 414

  Fly   361 EDAP--------------HRLDIRVGKVVEVARHPDADTLYVLKI 391
             |.|              ||.......|:.:.:|...:.|.:|||
  Rat   415 -DGPRGYRMITEGGVSINHRQVTNPESVLVIGQHILKNGLSLLKI 458

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TyrRS	NP_648895.1	nt_trans	8..334	CDD:294020	66/351 (19%)
		tyrS	12..332	CDD:272976	66/349 (19%)
		tRNA_bind_EMAP-II_like	364..466	CDD:239198	9/42 (21%)
Yars2	NP_001009627.1	PRK05912	37..468	CDD:235645	86/435 (20%)
		TyrRS_core	68..350	CDD:173902	62/307 (20%)
		'HIGH' region	76..85		4/8 (50%)
		'KMSKS' region	275..279		1/3 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0162
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900