DRSC/TRiP Functional Genomics Resources

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Protein Alignment TyrRS and yars-1

DIOPT Version :9

Sequence 1:NP_648895.1 Gene:TyrRS / 39829 FlyBaseID:FBgn0027080 Length:525 Species:Drosophila melanogaster
Sequence 2:NP_740947.2 Gene:yars-1 / 173311 WormBaseID:WBGene00013677 Length:722 Species:Caenorhabditis elegans


Alignment Length:326 Identity:191/326 - (58%)
Similarity:229/326 - (70%) Gaps:19/326 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 EKKALITRNLQETLGDDKLTKILAERDLK---IYWGTATTGKPHVAYFVPMSKIADFLKAGCEVT 69
            |.:.||.|||||:||.|||||.| |...|   :||||||||||||.|.|||.||||||:||.:||
 Worm    18 ETRELILRNLQESLGVDKLTKQL-ETPGKVPHVYWGTATTGKPHVGYLVPMRKIADFLQAGLKVT 81

  Fly    70 ILFADLHAYLDNMKAPWSLLELRTKYYEQVIKAMLSSIGVPLEKLKFVKGSDYQLSKEYTLDVYK 134
            ||||||||||||||:.|.||:.|..|||.||||:|.|:.||:|:|.|.||::||||:|||.||.:
 Worm    82 ILFADLHAYLDNMKSSWELLKCRVIYYENVIKALLQSLDVPIEQLYFKKGTEYQLSREYTDDVLR 146

  Fly   135 LSSVVTQHDAKKAGAEVVKQVEYPLLSGLLYPGLQALDEEYLKVDAQFGGVDQRKIFTFSEKYLP 199
            ||:.|:|.||.|||||||||||.|||||||||.||||||:|||||.|||||||||||..:|:.||
 Worm   147 LSAQVSQRDALKAGAEVVKQVESPLLSGLLYPLLQALDEQYLKVDGQFGGVDQRKIFILAEEQLP 211

  Fly   200 QLGYEKRIHFMNPMVPGLAGGKMSSSEEDSKIDLLDSPANVKKKLKKAFC---EPGNIADNGLLS 261
            :|...||.|.||||||||.|.||||||||||||:||.|..|:.|:..|.|   :|    |||:||
 Worm   212 KLKLGKRWHLMNPMVPGLTGTKMSSSEEDSKIDVLDEPEKVRSKIMGAACSRDQP----DNGVLS 272

  Fly   262 FVKHVLFSLFKEGEGFEVNREAEHGGDVTFLKYEDLEKYYAEDKLHPGDLKATVEKYINRLLDPI 326
            |...|||.:... ...|:..:       .|...:.|::.|.:.||....||..:..::..||:.:
 Worm   273 FYNFVLFPIVSP-NAIEIENQ-------QFFDIDSLKRAYLDGKLDENTLKTFLADFLVNLLEKV 329

  Fly   327 R 327
            |
 Worm   330 R 330

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
TyrRSNP_648895.1 nt_trans 8..334 CDD:294020 191/326 (59%)
tyrS 12..332 CDD:272976 190/322 (59%)
tRNA_bind_EMAP-II_like 364..466 CDD:239198
yars-1NP_740947.2 nt_trans 21..330 CDD:294020 189/321 (59%)
trpS 45..359 CDD:272975 174/298 (58%)
nt_trans 384..705 CDD:294020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 322 1.000 Domainoid score I654
eggNOG 1 0.900 - - E1_COG0162
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D557463at33208
OrthoFinder 1 1.000 - - FOG0000771
OrthoInspector 1 1.000 - - oto19533
orthoMCL 1 0.900 - - OOG6_101224
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R1461
SonicParanoid 1 1.000 - - X2335
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
1110.710

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