Protein Alignment GluRS-m and ears2

DIOPT Version :10

• Sequence 1: NP_648894.2
• Gene: GluRS-m / 39828
• FlyBaseID: FBgn0036629
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001418017.1
• Gene: ears2 / 751732
• ZFINID: ZDB-GENE-060825-214
• Length: 519
• Species: Danio rerio
• Alignment Length: 483
• Identity: 215/483 - (44%)
• Similarity: 295/483 - (61%)
• Gaps: 22/483 - (4%)

  Fly     2 LKINPRMLMQQCLRHAHSQVRVRFAPSPTGYLHLGGLRTALYNFLYARHLGGKFLLRIEDTDQTR 66
            :||...:..|.|.  :..:|||||||||||:||||||||||||||::|...|.|:||:|||||.|
Zfish     1 MKILRGVSRQMCT--SRPEVRVRFAPSPTGFLHLGGLRTALYNFLFSRQRRGVFILRLEDTDQKR 63

  Fly    67 LVPGASERLVEDLLWAGIEIDEGPGFGGQLGPYVQSQRTEIYSKAIEELLHNGTAYRCFCTERRL 131
            |||||:|.:.:.|.||||..||....||..||||||:|..:|::|...||:.|.||.|||:.:||
Zfish    64 LVPGAAEHIEDMLEWAGIPPDESSRRGGDYGPYVQSERLHLYTEAASSLLNTGHAYYCFCSNQRL 128

  Fly   132 DLLRKEALRTRQVPRYDNKCRHLTTSEVDSLLAKGTPYCIRFKLTDHEEPLDDLIYGKVHHNVSD 196
            :||:|||.|:...|||||:||.|...:|:..||.|.|..:||||....|...||::|...|.|..
Zfish   129 ELLKKEAQRSGHAPRYDNRCRRLQPQQVEQKLAAGVPAVVRFKLHMGTEEFQDLVFGWTGHAVGA 193

  Fly   197 NEGDPVVMKSDQFPTYHFANVVDDHLMGITHVLRGVEWQISTTKHLLLYKAFGWQPPKFGHLPLL 261
            .|||||::|.|.:||||.|:|||||.|.|:|||||.||.||:.|||.||:|..|.||.:.|||||
Zfish   194 VEGDPVILKGDGYPTYHLASVVDDHHMRISHVLRGCEWLISSAKHLQLYRALRWTPPTYAHLPLL 258

  Fly   262 VNADGTKLSKRQGDIGIQHFRERGYFPQALVNYVVSAGGGFEHRTNAKQQLLSMQALHEQFHIER 326
            :|.||:|||||||||.:|.||:||..|:.|::.|..||.||......::    :..|...|:|.:
Zfish   259 LNRDGSKLSKRQGDIFLQSFRDRGVLPETLLDLVTHAGSGFSDNRMGRR----LDELIRDFNISK 319

  Fly   327 VNSHPSRLNPELLDDLNRLEIVQRLSGNESRTKLVNEVQQLVKEAYPQHSNLD--LAEEHILDVL 389
            :.:|.:.|:.:.|::.:||.:.:|:...:....|..|::|:||..:....:..  |..|:|..||
Zfish   320 ITTHSALLDLDKLEEFSRLHLQRRIEDPQQCVWLCEELKQMVKHTHSSEISAAAVLEPEYIERVL 384

  Fly   390 NWSSKRLTLLQDLTSSKLSFLWVKP--SDFQIKDLTAEQLAHLLQLINAIQDF--------HKDE 444
            ......::.||||.||..|:|||:|  |..|::    .:.||...:..|:...        ..:.
Zfish   385 QLRKGHISSLQDLLSSTHSYLWVRPRVSQTQLQ----SESAHAKDIATAVMQMVLAGGSLVSMER 445

  Fly   445 LNVKLKSFAQKENIKFPLMMKTLRAALS 472
            ||.:||..:.:.|.....:||.||..||
Zfish   446 LNSELKQISSRTNSTHSSVMKVLRLLLS 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRS-m	NP_648894.2	GlnS	19..500	CDD:439779	211/466 (45%)
ears2	NP_001418017.1	GlnS	17..477	CDD:439779	211/465 (45%)
		'HIGH' region	26..34		6/7 (86%)
		'KMSKS' region	265..269		3/3 (100%)