Protein Alignment GluRS-m and Ears2

DIOPT Version :10

• Sequence 1: NP_648894.2
• Gene: GluRS-m / 39828
• FlyBaseID: FBgn0036629
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_001152965.1
• Gene: Ears2 / 361641
• RGDID: 1307904
• Length: 523
• Species: Rattus norvegicus
• Alignment Length: 498
• Identity: 237/498 - (47%)
• Similarity: 323/498 - (64%)
• Gaps: 31/498 - (6%)

  Fly    21 VRVRFAPSPTGYLHLGGLRTALYNFLYARHLGGKFLLRIEDTDQTRLVPGASERLVEDLLWAGIE 85
            |||||||||||:||||||||||||:::|:...|.|:||:|||||:||||||:|.:.:.|.||||.
  Rat    37 VRVRFAPSPTGFLHLGGLRTALYNYIFAKKHQGSFILRLEDTDQSRLVPGAAENIEDMLEWAGIP 101

  Fly    86 IDEGPGFGGQLGPYVQSQRTEIYSKAIEELLHNGTAYRCFCTERRLDLLRKEALRTRQVPRYDNK 150
            .||.|..||..|||.||||..:|::|.|.||.:|.||.|||:.:||:||:|||||:||.|||||:
  Rat   102 PDESPRQGGPAGPYYQSQRLALYAQATEALLKSGAAYPCFCSPQRLELLKKEALRSRQTPRYDNR 166

  Fly   151 CRHLTTSEVDSLLAKGTPYCIRFKLTDHEEPLDDLIYGKVHHNVSDNEGDPVVMKSDQFPTYHFA 215
            ||:|:.::|...||......|||:|.:......||:||...|.|:..|||||::|||.|||||.|
  Rat   167 CRNLSQAQVAQKLATDPKPAIRFRLEEAVPAFQDLVYGWTQHEVASVEGDPVILKSDGFPTYHLA 231

  Fly   216 NVVDDHLMGITHVLRGVEWQISTTKHLLLYKAFGWQPPKFGHLPLLVNADGTKLSKRQGDIGIQH 280
            .|||||.|.|:|||||.||.:||:||||||:|.|||||:|.|||||:|.||:|||||||||.::|
  Rat   232 CVVDDHHMSISHVLRGSEWLVSTSKHLLLYQALGWQPPQFAHLPLLLNRDGSKLSKRQGDIFLEH 296

  Fly   281 FRERGYFPQALVNYVVSAGGGFEHRTNAKQQL-LSMQALHEQFHIERVNSHPSRLNPELLDDLNR 344
            |...|:.|:||::.:.:.|.||     |:.|: .::..|..||.:.|:..|.:.|:.|.|.:.||
  Rat   297 FAATGFLPEALLDIITNCGSGF-----AENQMGRTLPELITQFDLTRITCHSALLDLEKLPEFNR 356

  Fly   345 LEIVQRLSGNESRTKLVNEVQQLVKEAYPQHSNLDLAEEHILD------VLNWSSKRLTLLQDLT 403
            |.:.:.:|....|..||.::|.|||||:    ..:|.:..:||      :|......::.||||.
  Rat   357 LHLRRLVSSETQRPHLVEKLQGLVKEAF----GSELQDRDVLDPAYMERILLLRQGHISRLQDLV 417

  Fly   404 SSKLSFLWVKPSDFQIK--------DLTAEQLAHLLQL--INAIQDFHKDELNVKLKSFAQ-KEN 457
            |...|:||.:|:..:.:        |:.|:.|..||:.  ::..||.    :|.:||..:: .|.
  Rat   418 SPVYSYLWTRPAVHRAELGASSEKLDVIAKHLLGLLERPGLSLTQDV----VNRELKKLSEGLEG 478

  Fly   458 IKFPLMMKTLRAALSGLKEGPGVAEMMEILGKSVTLERLKEAL 500
            .|...:||.||.||||..:||.|||||..||.....||:::.|
  Rat   479 TKHSSVMKLLRMALSGQLQGPPVAEMMVSLGPEEVRERIQKVL 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRS-m	NP_648894.2	GlnS	19..500	CDD:439779	236/496 (48%)
Ears2	NP_001152965.1	GlnS	36..521	CDD:439779	236/496 (48%)