Protein Alignment GluRS-m and ears-2

DIOPT Version :9

• Sequence 1: NP_648894.2
• Gene: GluRS-m / 39828
• FlyBaseID: FBgn0036629
• Length: 511
• Species: Drosophila melanogaster
• Sequence 2: NP_499917.2
• Gene: ears-2 / 176860
• WormBaseID: WBGene00001338
• Length: 481
• Species: Caenorhabditis elegans
• Alignment Length: 499
• Identity: 185/499 - (37%)
• Similarity: 278/499 - (55%)
• Gaps: 56/499 - (11%)

  Fly    21 VRVRFAPSPTGYLHLGGLRTALYNFLYARHLGGKFLLRIEDTDQTRLVPGASERLVEDLLWAGIE 85
            |||||||||||:||:||||||.:|:|:|:..||.|:|||||||:||.|..|.:::...|.:..:.
 Worm    11 VRVRFAPSPTGHLHIGGLRTAFFNYLFAKKYGGDFILRIEDTDRTRFVDDAQDQIYSSLNFYNLL 75

  Fly    86 IDEGPGFGGQLGPYVQSQRTEIYSKAIEELLHNGTAYRCFCTERRLDLLRKEALRTRQVPRYDNK 150
            .||||..||:.|||.||:|.|||..|...|:.:|.||||||:|.|||||||.|.:..::|:||.|
 Worm    76 PDEGPREGGKFGPYEQSKRLEIYRNAAYRLIDSGHAYRCFCSENRLDLLRKTAEKRGEIPKYDRK 140

  Fly   151 CRHLTTSEVDSLLAKGTPYCIRFKLTDHEEPLDDLIYGKVHHNVSDNEGDPVVMKSDQFPTYHFA 215
            |.:|::.:...:...|..:.|||||........|.::|.|:..:  :|.|||::|||.|||||.|
 Worm   141 CANLSSRDAVKMEQNGEKFVIRFKLDKQNVQFHDEVFGSVNQFI--DESDPVLLKSDGFPTYHLA 203

  Fly   216 NVVDDHLMGITHVLRGVEWQISTTKHLLLYKAFGWQPPKFGHLPLLVNADGTKLSKRQGDIGIQH 280
            ||:||..|.|:||:||:||..||.||.:|||||.|.||||.||.|::.:...|||||..|..:.:
 Worm   204 NVIDDRKMEISHVIRGMEWLSSTGKHTILYKAFNWTPPKFVHLSLIMRSATKKLSKRDKDAFVSY 268

  Fly   281 FRER-GYFPQALVNYVVSAGGGFEHRTNAKQQLLSMQALHEQFHIERVNSHPSRLNPELLDDLNR 344
            :.|: |..|:|::|.::..|.|.  |....:...|:..:.|||.:..:    .|.|  ||.|.:.
 Worm   269 YSEQLGALPEAVLNLMIRNGAGI--RNFDAEHFYSLDEMIEQFDLSLL----GRRN--LLLDSDV 325

  Fly   345 LEIVQRLSGNESRTKLVNEVQQLVKEAYPQHSNLDLAEEHILDVLNWSSKRLTLLQDL------- 402
            |:...|::..:|.          .||.||:          |:|:||..|...|..:|:
 Worm   326 LQKYSRMAFQKSD----------FKELYPR----------IIDILNKKSNYSTSREDIQKIVTFL 370

  Fly   403 ------------TSSKLSFLWVKPSDFQI--KDLTAEQLAHLLQLINAIQDFHKDELNVKLKSFA 453
                        .|::.|:.:.:|...|:  :......|.::|..:..|:.|:.:    .|:..|
 Worm   371 KAKEENFGFLSSLSTEFSWFFTRPQSSQLLKESHPNVDLRNILNSLLEIEVFNSE----SLEYLA 431

  Fly   454 QKENIKFPLMMKTLRAALSGLKEGPGVAEMMEILGKSVTLERLK 497
            :...:.....|..:|.:|.|.|:||.::|::|..|.:....|::
 Worm   432 KNHQLNLAKAMGIVRISLIGSKKGPPISELVEFFGMTECHRRIR 475

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GluRS-m	NP_648894.2	gltX	19..500	CDD:234953	185/499 (37%)
		GluRS_core	21..349	CDD:173905	151/328 (46%)
		Ribosomal_L7_L12	<442..503	CDD:305167	13/56 (23%)
ears-2	NP_499917.2	gltX	9..475	CDD:234953	185/497 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162627
Domainoid	1	1.000	292	1.000	Domainoid score	I820
eggNOG	1	0.900	-	-		E1_COG0008
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6907
Inparanoid	1	1.050	315	1.000	Inparanoid score	I1531
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG52070
OrthoDB	1	1.010	-	-		D309193at33208
OrthoFinder	1	1.000	-	-		FOG0003395
OrthoInspector	1	1.000	-	-		oto18274
orthoMCL	1	0.900	-	-		OOG6_101161
Panther	1	1.100	-	-	LDO	PTHR43311
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1434
SonicParanoid	1	1.000	-	-		X2748
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.800