Protein Alignment Serinc and TMS1

DIOPT Version :10

• Sequence 1: NP_001261947.1
• Gene: Serinc / 39827
• FlyBaseID: FBgn0028399
• Length: 467
• Species: Drosophila melanogaster
• Sequence 2: NP_010390.3
• Gene: TMS1 / 851682
• SGDID: S000002512
• Length: 473
• Species: Saccharomyces cerevisiae
• Alignment Length: 457
• Identity: 129/457 - (28%)
• Similarity: 216/457 - (47%)
• Gaps: 83/457 - (18%)

  Fly     1 MGAALGI---CSAAQCAMCCGGTAASMCCSACPSCTNAS------SSRFMYAFILLVGTVLGAIA 56
            |||.:.:   .:.:..|.|.||     |||...:.|.:|      .:|.:||..||:.:::..::
Yeast     1 MGAVISLPVSMAGSFVASCFGG-----CCSNLVTKTASSLGSSSLGTRLLYAVWLLLNSLISWVS 60

  Fly    57 LSPGLQDTLKKMPFCINSTSSYSSGALSAVSGGSLQVDCEYALGYMAVYRVCFGMACFFALMSLI 121
            .|.              :.|....|.....:|     :|    |:..|:|:.|.:.|...:::|:
Yeast    61 YSA--------------NKSILWPGKTCTGTG-----EC----GFFTVHRLNFALGCLHLILALV 102

  Fly   122 MLGVKSSRDPRSHIQNNFWPLKFLICFGAAIGAIFIPDGSFGPAMMWVGLIGGLAFILVQLVIIV 186
            :.||||:.|.|:.:||::|.|||::.....:.:..||:..:.....||.:..|..||||.|:::|
Yeast   103 LTGVKSTNDVRAALQNSWWSLKFILYLCLIVLSFVIPNDFYIFFSKWVSVPSGAIFILVGLILLV 167

  Fly   187 DFAHSLAE---NWIESAENSRGYY--YALAGVTLLCYILSLTGITLLYIYFTTSTGCGINKFFIS 246
            ||||..||   :.:||.:....::  :.:.|.|.: |..|:....::|:.|.... |.:|:..::
Yeast   168 DFAHEWAETCISHVESEDEDSSFWQRFLVLGTTSM-YTASIIMTVVMYVMFCHQQ-CNMNQTAVT 230

  Fly   247 INLIFCLAISVISILPAVQERLPHSGLLQSSLVTLYTVYLTWSAVANNP-EKECNP-------GM 303
            :|||..:...|:|:.|.:||..|.|||.|||:|::|..|||.||:::.| :|.|||       ..
Yeast   231 VNLILTVITLVLSVNPKIQEANPKSGLAQSSMVSVYCTYLTMSAMSSEPDDKMCNPLVRSSGTRK 295

  Fly   304 FGMMEGFGNATTTAAPPTHTTRV----TFDTTNIIGLVVWL--------------LCILYNCISS 350
            |.::  .|:..|..|....|||.    .|..||..| .::|              ..:.|..|..
Yeast   296 FSII--LGSLFTFIAIAYTTTRAAANSAFQGTNTNG-AIYLGNDIEYEGLGGQTRNQLRYEAIKQ 357

  Fly   351 AVEVSKISHDNSEKREALSDTE-AGTD---GSGKPSTDTETEGVTYSWSMFHLVFVCASLYVMMT 411
            |||      :.|....||.||. .||.   |:.....|.|..|..|::::||::|..|:.::.:.
Yeast   358 AVE------EGSLPESALYDTAWLGTSSPTGAMDNQNDDERTGTKYNYTLFHVIFFLATQWIAIL 416

  Fly   412 LT 413
            ||
Yeast   417 LT 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Serinc	NP_001261947.1	Serinc	14..417	CDD:460891	126/441 (29%)
TMS1	NP_010390.3	Serinc	10..466	CDD:460891	126/448 (28%)