Protein Alignment TMS1 and Serinc4

DIOPT Version :9

• Sequence 1: NP_001261947.1
• Gene: TMS1 / 39827
• FlyBaseID: FBgn0028399
• Length: 467
• Species: Drosophila melanogaster
• Sequence 2: NP_001020542.1
• Gene: Serinc4 / 574418
• MGIID: 2441842
• Length: 492
• Species: Mus musculus
• Alignment Length: 452
• Identity: 135/452 - (29%)
• Similarity: 209/452 - (46%)
• Gaps: 91/452 - (20%)

  Fly    14 AMCCGGTAASMCCSACPSCTNASSSRFMYAFILLVGTVLGAIALSP-----------GLQDTLKK 67
            |.|||..:.:   |.|.|.|.:..||.:|..:.:..:.:..:.||.           |:|
Mouse    34 ASCCGPVSWT---SGCHSLTESRCSRLLYILLHVGASAICCLLLSKTVVERVWGKAHGIQ----- 90

  Fly    68 MPFCINSTSSYSSGALSAVSGGSLQVDCEYALGYMAVYRVCFGMACFFALMSLIMLGVKSSRDPR 132
            ||           ..|.|...||  .||....|..||||||.|.|.|..|.:::::.:.|..:||
Mouse    91 MP-----------SVLCAHLFGS--SDCPVLSGSGAVYRVCAGTATFHLLQAVLLVRLHSPTNPR 142

  Fly   133 SHIQNNFWPLKFLICFGAAIGAIFIPDGSFGPAMMWVGLIGGLAFILVQLVIIVDFAHSLAENWI 197
            :.:.|:||.||.|...|..:.|..|||....||..::|:.||..|||:|||:|..||.|..:||.
Mouse   143 AQLHNSFWSLKLLFLLGLCVVAFCIPDEDLFPAWHYIGICGGFTFILLQLVLITAFAQSWNKNWQ 207

  Fly   198 ESAENSRGYYYALAGVTLLCYILSLTGITLLYIYFTTSTGCGINKFFISINLIFCLAISVISILP 262
            ..|.....:...::..||..|.::..|..||:..:|...||.:||..:|::|.||..:|::||.|
Mouse   208 TGAAQDCSWLLGVSLATLGFYSMAGVGAVLLFHQYTHPDGCLLNKMLLSLHLCFCGLLSLLSIAP 272

  Fly   263 AVQERLPHSGLLQSSLVTLYTVYLTWSAVANNPEKE----------CNPGMFGMMEGFGNATTTA 317
            .::.:.|:|||||:|:::.|.:|||:||:::.|.:.          |.||. ..||
Mouse   273 CIRRKQPNSGLLQASIISCYIMYLTFSALSSRPPETITFQGQNHTLCLPGR-NKME--------- 327

  Fly   318 APPTHTTRVTFDTTNIIGLVVWLLCILYNCISSA-----------VEVSKIS------------- 358
             |....|.|...:..|:     ..|:|:.|..::           ::|.|..
Mouse   328 -PQIPDTSVAVFSAGIM-----YACVLFACNEASYLAELFGPLWIIKVYKYEFQKPSVCFCCPQT 386

  Fly   359 ---HDNSEKREALSDTEAGTDGSGKPSTDTETEGVTYSWSMFHLVFVCASLYVMMTLTNWYN 417
               .|....|...:|.|.      .|:...:::.::||:|.||..|..||||||:|||||::
Mouse   387 VEPEDGQRSRARSADQET------PPAAQVQSQHLSYSYSGFHFAFFLASLYVMVTLTNWFS 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMS1	NP_001261947.1	Serinc	16..417	CDD:281358	134/448 (30%)
Serinc4	NP_001020542.1	Serinc	36..471	CDD:281358	134/450 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849128
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2592
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53917
OrthoDB	1	1.010	-	-		D1276632at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10383
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X262
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.860