Protein Alignment TMS1 and serinc1.1

DIOPT Version :9

• Sequence 1: NP_001261947.1
• Gene: TMS1 / 39827
• FlyBaseID: FBgn0028399
• Length: 467
• Species: Drosophila melanogaster
• Sequence 2: NP_001011399.1
• Gene: serinc1.1 / 496872
• XenbaseID: XB-GENE-954990
• Length: 460
• Species: Xenopus tropicalis
• Alignment Length: 438
• Identity: 196/438 - (44%)
• Similarity: 280/438 - (63%)
• Gaps: 30/438 - (6%)

  Fly     1 MGAALGICSAAQCAMCCGGTAASMCCSACPSCTNASSSRFMYAFILLVGTVLGAIALSPGLQDTL 65
            ||..||:|:||....|..|:|..:.|..|||..|::.:|.:|||.||:|..:..:.|.||:::.|
 Frog     1 MGGVLGLCTAASWIPCLCGSAPCLLCRCCPSGNNSTVTRLIYAFFLLIGVTVACVMLIPGMEEQL 65

  Fly    66 KKMP-FCINSTSSYSSGALSAVSGGSLQVDCEYALGYMAVYRVCFGMACFFALMSLIMLGVKSSR 129
            ||:| ||       ..|..|::.|.|..|:|:..:||.||||||||||.||.|.||:|:.||||:
 Frog    66 KKIPGFC-------DGGMGSSIPGISGHVNCDVLVGYKAVYRVCFGMAMFFLLFSLLMIKVKSSQ 123

  Fly   130 DPRSHIQNNFWPLKFLICFGAAIGAIFIPDGSFGPAMMWVGLIGGLAFILVQLVIIVDFAHSLAE 194
            |||:.:.|.||..||....|..:||.|||:|.|.....:||:.|...|||:|||:::|||||..|
 Frog   124 DPRASVHNGFWFFKFAAAVGITVGAFFIPEGPFTTVWFYVGMGGAFCFILIQLVLLIDFAHSWNE 188

  Fly   195 NWIESAE--NSRGYYYALAGVTLLCYILSLTGITLLYIYFTTSTGCGINKFFISINLIFCLAISV 257
            :|:|..|  |||.:|.||...|.:.|:|||..|.|.|:|:|...||..||.|||:|::.|:..|:
 Frog   189 SWVEKMEEGNSRCWYAALLSATGMNYVLSLVAIVLFYVYYTHPEGCAENKAFISVNMLLCIGASL 253

  Fly   258 ISILPAVQERLPHSGLLQSSLVTLYTVYLTWSAVANNPEKECNPGMFGMMEGFGNATTTAAPPTH 322
            :|:||.:||..|.|||||||::|:||:||||||:.|.|:::|||.:..:: |: |:|:|   |..
 Frog   254 MSVLPKIQESQPRSGLLQSSVITVYTMYLTWSAMTNEPDRKCNPSLLSII-GY-NSTST---PGQ 313

  Fly   323 TTRVT-FDTTNIIGLVVWLLCILYNCI--SSAVEVSKISHDNSEKREALSDTEAGTDGSGKPS-- 382
            ...|. :|...|:|||::|||:||:.|  |:..:|:|::..:.|  ..|.:....:|||.:.|
 Frog   314 VKVVQWWDAQGIVGLVLFLLCVLYSSIRTSNNSQVNKLTLTSDE--STLIEDGGRSDGSMEDSDN 376

  Fly   383 ----TDTETEGVTYSWSMFHLVFVCASLYVMMTLTNWYNNFLFPQTSF 426
                .|.|.:|||||:|.||.:...||||:||||||||:    |.:|:
 Frog   377 AHRAVDNERDGVTYSYSFFHFMLFLASLYIMMTLTNWYS----PDSSY 420

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMS1	NP_001261947.1	Serinc	16..417	CDD:281358	186/412 (45%)
serinc1.1	NP_001011399.1	Serinc	16..458	CDD:367456	189/423 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	358	1.000	Domainoid score	I970
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H41334
Inparanoid	1	1.050	364	1.000	Inparanoid score	I2117
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1276632at2759
OrthoFinder	1	1.000	-	-		FOG0000665
OrthoInspector	1	1.000	-	-		otm49081
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1919
SonicParanoid	1	1.000	-	-		X262
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.090