Protein Alignment TMS1 and Serinc3

DIOPT Version :9

• Sequence 1: NP_001261947.1
• Gene: TMS1 / 39827
• FlyBaseID: FBgn0028399
• Length: 467
• Species: Drosophila melanogaster
• Sequence 2: NP_001008313.1
• Gene: Serinc3 / 296350
• RGDID: 1308390
• Length: 472
• Species: Rattus norvegicus
• Alignment Length: 463
• Identity: 185/463 - (39%)
• Similarity: 267/463 - (57%)
• Gaps: 54/463 - (11%)

  Fly     1 MGAALGICSAAQCAMC-CGGTAASMCCSACPSCTNASSSRFMYAFILLVGTVLGAIALSPGLQDT 64
            |||.||:.|.|....| |.| |:.:.||.||...|::.:|.:||.||::||::..|.::.|:|..
  Rat     1 MGAVLGVFSLASWVPCLCSG-ASCLLCSCCPMSKNSTVTRLIYASILILGTIVSCIMMTEGIQTQ 64

  Fly    65 LKKMP-FCINSTSSYSSGALSAVSGGSLQV---------DCEYALGYMAVYRVCFGMACFFALMS 119
            |||:| ||                .|..|:         ||:..:|:.||||:.|.:|.||....
  Rat    65 LKKIPGFC----------------EGEFQIKIVDTKAEKDCDVLVGFKAVYRINFAVAIFFFAFF 113

  Fly   120 LIMLGVKSSRDPRSHIQNNFWPLKFLICFGAAIGAIFIPDGSFGPAMMWVGLIGGLAFILVQLVI 184
            |:||.||:|:|||:.:.|.||..|.....|..:|:.:||.|.|.......|::|...||.:|||:
  Rat   114 LLMLKVKTSKDPRAAVHNGFWFFKIAAIIGIMVGSFYIPGGHFTKVWFSAGMLGATFFIFIQLVL 178

  Fly   185 IVDFAHSLAENWIESAE--NSRGYYYALAGVTLLCYILSLTGITLLYIYFTTSTGCGINKFFISI 247
            :||.|||..|.|:...|  |.|.:|.||...|.|.||||:....||||::|...||..||.|||:
  Rat   179 LVDLAHSWNELWVNRMEEGNPRLWYAALLSFTSLFYILSIVFAALLYIFYTKPDGCTENKVFISL 243

  Fly   248 NLIFCLAISVISILPAVQERLPHSGLLQSSLVTLYTVYLTWSAVANNPEKECNPGMFGMMEGF-- 310
            |||||:|:|::||||.|||..|.|||||||::||||:||||||:.|.|::.|||.:..::...
  Rat   244 NLIFCVAVSIVSILPKVQEHQPRSGLLQSSIITLYTLYLTWSAMTNEPDRSCNPSLMSIITQLTS 308

  Fly   311 -----GNATTTA---APPTHTTR-VTFDTTNIIGLVVWLLCILYNCI--SSAVEVSKISHDNSEK 364
                 .|:||.|   .||:.... :..|  ::.||.::::|::|:.|  ||..:|:|::...|:.
  Rat   309 PTVSPANSTTPAPAYVPPSQNGHFINLD--DLGGLTIFVICLIYSSIRTSSNSQVNKLTLSGSDS 371

  Fly   365 REALSDTEAGT----DGSGKPSTDTETEGVTYSWSMFHLVFVCASLYVMMTLTNWYNNFLFPQTS 425
             ..|.||..|.    ||..:.:.|.|.:||.|::|.|||:..|||||:|||:|:||:    |...
  Rat   372 -VILGDTTNGASDEEDGRPRRAVDNEKDGVQYNYSFFHLMLCCASLYIMMTITSWYS----PDAK 431

  Fly   426 FGNRAVQR 433
            |...:.:|
  Rat   432 FQKVSSER 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMS1	NP_001261947.1	Serinc	16..417	CDD:281358	174/430 (40%)
Serinc3	NP_001008313.1	Serinc	17..470	CDD:281358	177/447 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352741
Domainoid	1	1.000	338	1.000	Domainoid score	I1072
eggNOG	1	0.900	-	-		E1_KOG2592
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	352	1.000	Inparanoid score	I2193
OMA	1	1.010	-	-		QHG53917
OrthoDB	1	1.010	-	-		D1276632at2759
OrthoFinder	1	1.000	-	-		FOG0000665
OrthoInspector	1	1.000	-	-		otm45997
orthoMCL	1	0.900	-	-		OOG6_101085
Panther	1	1.100	-	-	O	PTHR10383
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X262
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.810