Protein Alignment TMS1 and R11H6.2

DIOPT Version :9

• Sequence 1: NP_001261947.1
• Gene: TMS1 / 39827
• FlyBaseID: FBgn0028399
• Length: 467
• Species: Drosophila melanogaster
• Sequence 2: NP_506611.1
• Gene: R11H6.2 / 179964
• WormBaseID: WBGene00011250
• Length: 442
• Species: Caenorhabditis elegans
• Alignment Length: 428
• Identity: 176/428 - (41%)
• Similarity: 250/428 - (58%)
• Gaps: 41/428 - (9%)

  Fly     1 MGAALGICSAAQCAMCC-GGTAASMCCSACPSCTNASSSRFMYAFILLVGTVLGAIALSPGLQDT 64
            |||.|.....|..|.|| |.:|.|:||||||...|::::|.|||.:|:..|.:..:.|.||:|..
 Worm     1 MGALLAAPFCAASAACCFGSSACSLCCSACPGAKNSTTTRIMYALMLISATFMAVVMLLPGVQKK 65

  Fly    65 LKKMPFCINSTSSYSSGALSAVSGGSLQVDCEYALGYMAVYRVCFGMACFFALMSLIMLGVKSSR 129
            |.:..:..:..:.|:.            |:||:|:||.||||||.|.|.||.|..|:|.||.||:
 Worm    66 LVENKWLCDGLNEYAG------------VNCEHAIGYQAVYRVCAGAASFFFLFMLLMFGVSSSK 118

  Fly   130 DPRSHIQNNFWPLKFLICFGAAIGAIFIPDGSFGPAMMWVGLIGGLAFILVQLVIIVDFAHSLAE 194
            |.||.|||.||..|:|:.||...|..||...:....:|::|::|...|||:||::||||||.|||
 Worm   119 DGRSSIQNGFWFFKYLLMFGIIGGFFFIGSETLATPLMYIGMLGAFLFILIQLILIVDFAHGLAE 183

  Fly   195 NWIESAENSRGYYYALAGVTLLCYILSLTGITLLYIYFTTSTGCGINKFFISINLIFCLAISVIS 259
            :..|. .:||..|..|...|...:::.|.....::|.:....|||:.|||:..|::.|:|||::|
 Worm   184 SQYED-NDSRACYAGLLITTFGGFLVCLIAAVYVFINYAIGDGCGLPKFFVIFNVLICVAISLLS 247

  Fly   260 ILPAVQERLPHSGLLQSSLVTLYTVYLTWSAVANNPEKECNPGMFGMMEGFGNATTTAAPPTHTT 324
            :.|.|||..|.|||||..:::.|.:||||||:.:||.:.|||.:       .|.|.:|.|   |.
 Worm   248 VSPMVQEVNPRSGLLQPVVISAYIIYLTWSALLSNPNESCNPTL-------ANVTQSAIP---TG 302

  Fly   325 RVTFDTT--------NIIGLVVWLLCILYNCI--SSAVEVSKISHDNSEKREALSDTEAGTDGSG 379
            .||.|.:        ::|.|::||:|::|..|  ||...:.||:.|| |:...|:|.|.|
 Worm   303 GVTKDDSFVTPLPVHSLISLLIWLICLVYASIRNSSNTSLGKITGDN-EEHVQLNDVEGG----- 361

  Fly   380 KPSTDTETEGVTYSWSMFHLVFVCASLYVMMTLTNWYN 417
             .:.|.|.|||.||:|.||.:|..||||||||||:||:
 Worm   362 -KAWDNEEEGVAYSYSFFHFMFCLASLYVMMTLTSWYH 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMS1	NP_001261947.1	Serinc	16..417	CDD:281358	169/411 (41%)
R11H6.2	NP_506611.1	Serinc	19..441	CDD:281358	168/410 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166281
Domainoid	1	1.000	319	1.000	Domainoid score	I668
eggNOG	1	0.900	-	-		E1_KOG2592
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41334
Inparanoid	1	1.050	326	1.000	Inparanoid score	I1462
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53917
OrthoDB	1	1.010	-	-		D1276632at2759
OrthoFinder	1	1.000	-	-		FOG0000665
OrthoInspector	1	1.000	-	-		otm14280
orthoMCL	1	0.900	-	-		OOG6_101085
Panther	1	1.100	-	-	O	PTHR10383
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1919
SonicParanoid	1	1.000	-	-		X262
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.840