Protein Alignment TMS1 and Y57E12AL.1

DIOPT Version :9

• Sequence 1: NP_001261947.1
• Gene: TMS1 / 39827
• FlyBaseID: FBgn0028399
• Length: 467
• Species: Drosophila melanogaster
• Sequence 2: NP_741561.1
• Gene: Y57E12AL.1 / 179093
• WormBaseID: WBGene00021956
• Length: 459
• Species: Caenorhabditis elegans
• Alignment Length: 432
• Identity: 179/432 - (41%)
• Similarity: 253/432 - (58%)
• Gaps: 34/432 - (7%)

  Fly     1 MGAALGICSAAQCAMCCGGTAA-SMCCSACPSCTNASSSRFMYAFILLVGTVLGAIALSPGLQDT 64
            |||.|...:.|..:.||.|:|| |:|||.||:..:::::|.||||:|...|.|..|.|.||:|:.
 Worm     1 MGALLAAPACAASSACCFGSAACSLCCSICPTTKSSTTTRIMYAFLLFTSTFLSCIMLLPGIQNK 65

  Fly    65 LKKMPFCINSTSSYSSGALSAVSGGSLQVDCEYALGYMAVYRVCFGMACFFALMSLIMLGVKSSR 129
            |.:..:.....:.|:.            :.|.:|.|:.||||||...|.|:.|..|||:|||.|:
 Worm    66 LAENKWFCEGLNEYAG------------ISCAHATGFQAVYRVCAATASFYLLFMLIMIGVKDSK 118

  Fly   130 DPRSHIQNNFWPLKFLICFGAAIGAIFIPDGSFGPAMMWVGLIGGLAFILVQLVIIVDFAHSLAE 194
            |.||.|||.||..|:||.....:|..||...|....:|::|||||..|||:||::||||||.|||
 Worm   119 DGRSSIQNGFWFFKYLILGALIVGFFFIRSESLATPLMYIGLIGGFMFILIQLILIVDFAHGLAE 183

  Fly   195 NWIESAENSR-GYYYALAGVTLL-CYILSLTGITLLYIYFTTSTGCGINKFFISINLIFCLAISV 257
            .|:.|.|.|. .|.||...||:. .:.|:||.:.::|||:.:..|||:.:||:..|.:.|:.::.
 Worm   184 AWVTSYEESESNYCYAGLLVTVFGGFALALTAVIIMYIYYASGEGCGLPRFFVIFNTLLCVGLTA 248

  Fly   258 ISILPAVQERLPHSGLLQSSLVTLYTVYLTWSAVANNPEKECNPGMFGMMEGFGNATTTAAPPTH 322
            :|:.|||||..|.|||:|:.::|.|.:||||:|:.|||:|.|||.:..:..  ||:|    .|:|
 Worm   249 LSLAPAVQEVSPRSGLVQAVMITGYVMYLTWAALINNPDKACNPSLISIFT--GNST----DPSH 307

  Fly   323 TT-----RVTFDTTNIIGLVVWLLCILYNCI--SSAVEVSKISHDNSEKREA--LSDTEAGTDG- 377
            .|     .:.....:|:.|.:|..|:||..|  ||...:.||:...:...||  ||.:..|.|.
 Worm   308 KTDEGHYGIPLPAQSIVSLFLWFACLLYASIRNSSNTSLGKITGGGNTSDEAIQLSSSLNGADDA 372

  Fly   378 ---SGKPSTDTETEGVTYSWSMFHLVFVCASLYVMMTLTNWY 416
               :.|...|.|.|||.||:|.||.:|..||||||||||:||
 Worm   373 ESQNSKRVYDNEEEGVAYSYSFFHFMFALASLYVMMTLTSWY 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMS1	NP_001261947.1	Serinc	16..417	CDD:281358	174/417 (42%)
Y57E12AL.1	NP_741561.1	Serinc	18..458	CDD:281358	172/415 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166282
Domainoid	1	1.000	319	1.000	Domainoid score	I668
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41334
Inparanoid	1	1.050	326	1.000	Inparanoid score	I1462
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53917
OrthoDB	1	1.010	-	-		D1276632at2759
OrthoFinder	1	1.000	-	-		FOG0000665
OrthoInspector	1	1.000	-	-		otm14280
orthoMCL	1	0.900	-	-		OOG6_101085
Panther	1	1.100	-	-	LDO	PTHR10383
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1919
SonicParanoid	1	1.000	-	-		X262
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.940