Protein Alignment fax and FAXC

DIOPT Version :10

• Sequence 1: NP_524106.3
• Gene: fax / 39826
• FlyBaseID: FBgn0014163
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_115900.1
• Gene: FAXC / 84553
• HGNCID: 20742
• Length: 409
• Species: Homo sapiens
• Alignment Length: 303
• Identity: 90/303 - (29%)
• Similarity: 146/303 - (48%)
• Gaps: 39/303 - (12%)

  Fly   103 KDIIYLYQFSR-TPLLPSLSPYCLKVETWLRLVGLKYEN-VDHKMRFRSKKGQLPFIELNGEEIA 165
            ||.|.|:||:| ...:|||||:|||:||:||:..|.|:| ...|:   |.:|::|:||.|.|:::
Human    97 KDAIILHQFARPNNGVPSLSPFCLKMETYLRMADLPYQNYFGGKL---SAQGKMPWIEYNHEKVS 158

  Fly   166 DSAIIIKELSSKYEKYLDSGLTAEQRNVSYATIAMLENHLIWIIFYWRAKYPDNVLKGYKVNLQH 230
            .:..||..|..|....|:..|...:|.:|.|...|:|.|..|.:.|  .::.||:.:..|: |..
Human   159 GTEFIIDFLEEKLGVNLNKNLGPHERAISRAVTKMVEEHFYWTLAY--CQWVDNLNETRKM-LSL 220

  Fly   231 ALGLRLPNSILNFFFKITFGRKWFQGTKKLKAHGIGVHSAEEIEEFGKDDLKVLSEMLDCKPFFF 295
            :.|....|.:......||.|..    .:::..||||..|.|||....:.|::.|:.:|..|.:..
Human   221 SGGGPFSNLLRWVVCHITKGIV----KREMHGHGIGRFSEEEIYMLMEKDMRSLAGLLGDKKYIM 281

  Fly   296 GDEPTTLDVVAFAVLSQLHYLSKDIAYPLRDYMTEKCPNLIGHVSRMKDKCFPDW--DEICTKLD 358
            |.:.:|||...|..|:|..:.... ..|.| .:..:..||..:..|::.|.:|:|  |:..|..
Human   282 GPKLSTLDATVFGHLAQAMWTLPG-TRPER-LIKGELINLAMYCERIRRKFWPEWHHDDDNTIY- 343

  Fly   359 LNAHIPKPEPETKEGKEGGE------------QEKSNEQEGTE 389
                      |::|..||.:            :.::.|.||.|
Human   344 ----------ESEESSEGSKTHTPLLDFSFYSRTETFEDEGAE 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fax	NP_524106.3	GST_N_Metaxin_like	105..179	CDD:239378	32/75 (43%)
		GST_C_Metaxin	<272..343	CDD:198302	18/70 (26%)
FAXC	NP_115900.1	FAXC_N	1..106	CDD:466044	5/8 (63%)
		GST_N_4	117..212	CDD:465370	35/99 (35%)
		GST_C_6	263..326	CDD:465369	15/64 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	372..409		3/5 (60%)