DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fax and Faxc

DIOPT Version :9

Sequence 1:	NP_524106.3	Gene:	fax / 39826	FlyBaseID:	FBgn0014163	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_780443.2	Gene:	Faxc / 76132	MGIID:	1923382	Length:	409	Species:	Mus musculus

Alignment Length:	303	Identity:	91/303 - (30%)
Similarity:	146/303 - (48%)	Gaps:	39/303 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   103 KDIIYLYQFSR-TPLLPSLSPYCLKVETWLRLVGLKYEN-VDHKMRFRSKKGQLPFIELNGEEIA 165
            ||.|.|:||:| ...:|||||:|||:||:||:..|.|:| ...|:   |.:|::|:||.|.|:::
Mouse    97 KDAIILHQFARPNNGVPSLSPFCLKMETYLRMADLPYQNYFGGKL---SAQGKMPWIEYNNEKVS 158

  Fly   166 DSAIIIKELSSKYEKYLDSGLTAEQRNVSYATIAMLENHLIWIIFYWRAKYPDNVLKGYKVNLQH 230
            .:..||..|..|....|:..|...:|.||.|...|:|.|..|.:.|  .::.||:.:..|: |..
Mouse   159 GTEFIIDFLEEKLGVNLNKSLGPHERAVSRAVTKMVEEHFYWTLAY--CQWVDNLNETRKM-LSL 220

  Fly   231 ALGLRLPNSILNFFFKITFGRKWFQGTKKLKAHGIGVHSAEEIEEFGKDDLKVLSEMLDCKPFFF 295
            :.|....|.:......||.|..    .:::..||||..|.|||....:.|::.|:.:|..|.:..
Mouse   221 SGGGPFSNLLRWVVCHITKGIV----KREMHGHGIGRFSEEEIYMLMEKDMRSLAGLLGDKKYIM 281

  Fly   296 GDEPTTLDVVAFAVLSQLHYLSKDIAYPLRDYMTEKCPNLIGHVSRMKDKCFPDW--DEICTKLD 358
            |.:.:|||...|..|:|..:.... ..|.| .:..:..||..:..|::.|.:|:|  |:..|..
Mouse   282 GPKLSTLDATVFGHLAQAMWTLPG-TRPER-LIKGELINLAMYCERIRRKFWPEWHHDDDNTIY- 343

  Fly   359 LNAHIPKPEPETKEGKEGGE------------QEKSNEQEGTE 389
                      |::|..||.:            :.::.|.||.|
Mouse   344 ----------ESEESSEGSKTHTPMLDFSFYSRTETFEDEGAE 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fax	NP_524106.3	GST_N_Metaxin_like	105..179	CDD:239378	32/75 (43%)
fax	NP_524106.3	GST_C_Metaxin	<272..343	CDD:198302	18/70 (26%)
Faxc	NP_780443.2	GST_N_Metaxin_like	99..172	CDD:239378	32/75 (43%)
		GST_C_Metaxin	187..327	CDD:198302	40/148 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	372..393		3/5 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849467
Domainoid	1	1.000	62	1.000	Domainoid score	I10361
eggNOG	1	0.900	-	-		E1_KOG4244
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I4960
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55848
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001184
OrthoInspector	1	1.000	-	-		oto93117
orthoMCL	1	0.900	-	-		OOG6_103089
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4319
SonicParanoid	1	1.000	-	-		X3312
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.690