DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fax and faxcb

DIOPT Version :9

Sequence 1:	NP_524106.3	Gene:	fax / 39826	FlyBaseID:	FBgn0014163	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	XP_692250.4	Gene:	faxcb / 563796	ZFINID:	ZDB-GENE-100922-19	Length:	403	Species:	Danio rerio

Alignment Length:	335	Identity:	91/335 - (27%)
Similarity:	162/335 - (48%)	Gaps:	55/335 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   103 KDIIYLYQFSRTPL-LPSLSPYCLKVETWLRLVGLKYE-NVDHKMRFRSKKGQLPFIELNGEEIA 165
            ||.|.|:||||... :|||||:|||:||:||::.|.|: ..|..:   |.:|::|:||.|.|::.
Zfish    95 KDAIILHQFSRPKNGVPSLSPFCLKMETYLRMLDLPYQCYFDGSL---SAQGKMPWIEYNYEQVC 156

  Fly   166 DSAIIIKELSSKYEKYLDSGLTAEQRNVSYATIAMLENHLIWIIFYWRAKYPDNVLKGYKVNLQH 230
            .:..||:.|..|....|:..|:|:::.|:.|...|:|.||.|.|.|  .::.|||.:..::
Zfish   157 GTEFIIEFLEEKLGMSLNKSLSAQEQAVAQAITTMVEEHLYWSIAY--CQWVDNVQETQRM---- 215

  Fly   231 ALGLRLPNSILNFFFKITFGRKWF--QGT-----KKLKAHGIGVHSAEEIEEFGKDDLKVLSEML 288
               |.||..:.:..       ||.  |.|     :::..||||..:.:|:....:.|::.|:.:|
Zfish   216 ---LDLPGPLSDLL-------KWILCQLTGGMVKREMYCHGIGSFTKDEVYSLMEKDMRTLATLL 270

  Fly   289 DCKPFFFGDEPTTLDVVAFAVLSQLHYLSKDIAYP---LRDYMTEKCPNLIGHVSRMKDKCFPDW 350
            ..|.:..|.:.:::|...|..|:|..:     ..|   ....:..:..||..:..|::.|.:|:|
Zfish   271 GDKKYIMGPKLSSVDATVFGHLAQAMW-----TLPGTRPEQLIKGELINLAMYCERIRRKFWPEW 330

  Fly   351 ----DEIC--TKLDLNAHIPKPEP---------ETKEGKEGGEQEKSNEQEGTEGDKI-EKELEK 399
                ::.|  :..|.|:..| |.|         :|.|..:......||.:  ..|..: :.::|.
Zfish   331 FVDLEDFCYDSDNDTNSGTP-PCPLDLGLFSRTDTLEESDLSLPSHSNSE--LSGHSLSDSDIEV 392

  Fly   400 DKSNEKESTE 409
            |.|:.::..:
Zfish   393 DGSDGEQKVK 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fax	NP_524106.3	GST_N_Metaxin_like	105..179	CDD:239378	32/75 (43%)
fax	NP_524106.3	GST_C_Metaxin	<272..343	CDD:198302	14/73 (19%)
faxcb	XP_692250.4	GST_N_Metaxin_like	97..170	CDD:239378	32/75 (43%)
faxcb	XP_692250.4	GST_C_Metaxin	253..323	CDD:198302	14/74 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595149
Domainoid	1	1.000	64	1.000	Domainoid score	I10129
eggNOG	1	0.900	-	-		E1_KOG4244
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I4938
OMA	1	1.010	-	-		QHG55848
OrthoDB	1	1.010	-	-		D1180930at2759
OrthoFinder	1	1.000	-	-		FOG0001184
OrthoInspector	1	1.000	-	-		otm24954
orthoMCL	1	0.900	-	-		OOG6_103089
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4319
SonicParanoid	1	1.000	-	-		X3312
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.740