DRSC/TRiP Functional Genomics Resources

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Protein Alignment RAF2 and Y49E10.29

DIOPT Version :9

Sequence 1:NP_001261943.1 Gene:RAF2 / 39821 FlyBaseID:FBgn0036624 Length:1117 Species:Drosophila melanogaster
Sequence 2:NP_001122731.1 Gene:Y49E10.29 / 6418662 WormBaseID:WBGene00045239 Length:559 Species:Caenorhabditis elegans


Alignment Length:531 Identity:176/531 - (33%)
Similarity:226/531 - (42%) Gaps:138/531 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   265 SACRELEQALKDRSRDAPNEAESLVVDA-TLKRRRSVTPPASEEKRNNEVEDDNIIGFSTVQ--- 325
            |..::.:||   ::...|.:|:.:|... ..:::::..|||:::             ...||   
 Worm    30 SPAQQQQQA---QAHAPPAQAKPIVQQTQPAQKQQAQAPPAAQQ-------------IPVVQQAP 78

  Fly   326 -----QQKPMEAAPPLNLRMPTTPSTNPLQRQQAFKLSTPYTLAPPT-AAKQADTYSLNTPPPTA 384
                 ||||:..|||...: ||......|..|           |||. .|.||..:.. ..||.|
 Worm    79 PAQPAQQKPVAQAPPAQAK-PTVQQAPILVAQ-----------APPNPPAPQAQQHQA-PAPPAA 130

  Fly   385 TQMQISYPNEKLSNNMKANATFSIQQTALSQVAASYAAAP--QVAALAQRAPSQVAPLQQAPVQQ 447
            .|:.:..|.:.:           :||....|...|.|.||  |...:.|:|.:|.. :|:||.||
 Worm   131 RQIPVQQPPKPV-----------VQQAPAQQAPKSVAQAPPAQAKPIVQQAQAQPV-VQKAPTQQ 183

  Fly   448 MHFPRSVPP--QQLPPPQQRAPPQQLATAPFAPPRHLAQHRPSPQQLAPSQQLAPPHQLAPPHQL 510
                   ||  ||.|||||  |..|...|..|||     .:|...|..|..|.|||.|.|.|..:
 Worm   184 -------PPVVQQTPPPQQ--PVVQAPVAQQAPP-----SQPQQAQAQPVVQQAPPVQQASPKPV 234

  Fly   511 APPQQRAPPQQLAPPH---QLAPPHQLAPP--QQRA-------PP------QQLAPPQQLAPPQ- 556
            |.|.|:.|..| |||.   |.||..|.|||  ||:|       ||      ||.:.|.|.|||: 
 Worm   235 AQPVQQQPVVQ-APPKPIVQQAPVVQQAPPPKQQQAQAQPVQQPPNPAPVVQQASAPVQQAPPKP 298

  Fly   557 --QLAPPQQLAPP----QQL------APPQ---QRAPPQQRAPP-----QQLAPPQQRAPTQHMA 601
              |..||.|.|||    ||.      |||:   |:|||.|:.||     |..||..|:||    |
 Worm   299 VPQQTPPVQQAPPKPAVQQAPTRAAPAPPKPAPQQAPPVQQNPPKPAVQQAQAPVVQQAP----A 359

  Fly   602 PPQHMAPPQQLAPTQQLAPPPQQLAPRPQ-QLAPPPQQL--APP---PQQLAPPPQQPDSSRPAS 660
            ||...|||:   ||.|.|||.:|..|.|. |.||..||.  |||   |||..|..|.|....|: 
 Worm   360 PPVQQAPPK---PTPQQAPPVRQNPPMPAVQQAPSSQQATQAPPKPAPQQAPPVQQNPPKPTPS- 420

  Fly   661 VQPLTPQRHASPHQLAQSQQVHQSPSQLHPVPVAAPNF---------AVPQQPQPRRSETVSTQT 716
              |..|.:.|.|....|:.....|||    .||.|||.         .:.||..|.:..::|::.
 Worm   421 --PAPPAQKAQPVTQQQASAPPTSPS----APVQAPNTPTQKASSQDPIVQQDPPPKEPSISSEP 479

  Fly   717 QGLGSPAASSS 727
            .....|..|.|
 Worm   480 TTTKKPRKSFS 490

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RAF2NP_001261943.1 zf-MYND 1078..1115 CDD:280009
Y49E10.29NP_001122731.1 DUF3275 <425..>485 CDD:288521 15/63 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_2CSWZ
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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