DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RAF2 and Deaf1

DIOPT Version :9

Sequence 1:	NP_001261943.1	Gene:	RAF2 / 39821	FlyBaseID:	FBgn0036624	Length:	1117	Species:	Drosophila melanogaster
Sequence 2:	NP_001262069.1	Gene:	Deaf1 / 40164	FlyBaseID:	FBgn0013799	Length:	576	Species:	Drosophila melanogaster

Alignment Length:	231	Identity:	50/231 - (21%)
Similarity:	88/231 - (38%)	Gaps:	68/231 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   943 PAKRPKLIHSQDSNQDMASSSTHLSA--NLSETLRKIRAWKNYSHFSNVSMEDNNS-----DN-E 999
            |.::....||.::|.:..:::|..|.  |..:....:.|       :..|:.|.|:     :| .
  Fly   337 PKRKRNTHHSNNNNSNTNNNNTSGSGANNCVDVTAAVAA-------ATASVVDENNMFLSEENIT 394

  Fly  1000 SQIEP-------LFNSSPMASRRQLANRQSYQ-EQHSANINDHENVQKRHKSHKRKSHKH----- 1051
            |:.||       |..|:.:..:.|:.|  :|: |....||||..::.....|...|:.:|
  Fly   395 SKDEPWAALNDSLDTSTELVDQSQMGN--TYERETFVVNINDGSSIAVLDTSQSMKNIEHVYCTM 457

  Fly  1052 ---------------KSHKHR------------SSHKSQAES-------SATINGN---TGRQCH 1079
                           :|.:.|            |:.:.|..:       |.:::||   :.::|.
  Fly   458 VKATNDFKRMLNDMKQSFERRIEVLQKERDAAVSAMRVQVHADIDDPNISGSLHGNEIISAKKCA 522

  Fly  1080 ECKLYGATFMCSNCQNQWYCSRECQLSDWDTHHRTC 1115
            .|. ..|...||.|:...|||..||..||:.|...|
  Fly   523 NCN-REALAECSLCRKTPYCSEFCQRKDWNAHQVEC 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RAF2	NP_001261943.1	zf-MYND	1078..1115	CDD:280009	14/36 (39%)
Deaf1	NP_001262069.1	SAND	219..291	CDD:128554
Deaf1	NP_001262069.1	zf-MYND	521..557	CDD:280009	14/36 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10237
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100