DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Agpat3 and Agpat4

DIOPT Version :9

Sequence 1:	NP_001246793.1	Gene:	Agpat3 / 39820	FlyBaseID:	FBgn0036623	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_006523408.3	Gene:	Agpat4 / 68262	MGIID:	1915512	Length:	458	Species:	Mus musculus

Alignment Length:	381	Identity:	150/381 - (39%)
Similarity:	229/381 - (60%)	Gaps:	25/381 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LKQLRLIHLCIALTFFTSGLCINFIQLLMHVFIKPIDKRLFRKLMYYACYSLYSQLIFVSDWYAG 82
            ||...|.||.....|..|||.:|.|||...| |.||:|:||||:....||.:.|||:.:.:|::|
Mouse    87 LKSQFLCHLVFCYVFIASGLIVNAIQLCTLV-IWPINKQLFRKINARLCYCVSSQLVMLLEWWSG 150

  Fly    83 SKMTVYMDKEDFEKHAGKEHVLLIMNHKYEIDWLNGWMICEKLGVLGNCKAYAKKAIRYVPIIGW 147
            ::.|:|.|.:.. .|.|||:.::::|||:|||:|.||.:.|:||:|||.|..|||.:.|||||||
Mouse   151 TECTIYTDPKAC-PHYGKENAIVVLNHKFEIDFLCGWSLAERLGILGNSKVLAKKELAYVPIIGW 214

  Fly   148 GWWLAEFVFLNRNFDQDKTIITEQLKVVFSYPDPTWLLLNAEGTRFTPAKHEASVKFAQERGMTV 212
            .|:..|.:|..|.::||:..:.:.|..:..||:....|::.||||||..||:.|::.||.:|:..
Mouse   215 MWYFVEMIFCTRKWEQDRQTVAKSLLHLRDYPEKYLFLIHCEGTRFTEKKHQISMQVAQAKGLPS 279

  Fly   213 LKHHLIPRTKGFTASLAPIRGLCPVIYDINLAYRPTDKTPATMLSLLHGKSVEPHLLMRRIPLEQ 277
            |||||:||||||..::..:|.:.|.:||..|.:| .::.| |:|.:|:||.......:||||:|.
Mouse   280 LKHHLLPRTKGFAITVKCLRDVVPAVYDCTLNFR-NNENP-TLLGVLNGKKYHADCYVRRIPMED 342

  Fly   278 VPEDEKEAAAWLQNLFVEKDKIIDSFLETGSFFKTSGIKEVPAYVNKRRLCSLVNFVCWAVFSLS 342
            :||||.:.:|||..|:.|||...:.:..||.|      .|.| :|..||..||||::.||...|.
Mouse   343 IPEDEDKCSAWLHKLYQEKDAFQEEYYRTGVF------PETP-WVPPRRPWSLVNWLFWASLLLY 400

  Fly   343 CIFYYVITSLLAANWTAFITALSVLGLF-------YWLMGQAINKTQISKASNYGS 391
            ..|.::::.:.:.   :.:|..|::.:|       .|::|    .|:|.|.|.||:
Mouse   401 PFFQFLVSMVSSG---SSVTLASLVLIFCMASMGVRWMIG----VTEIDKGSAYGN 449

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat3	NP_001246793.1	PLN02380	23..387	CDD:178006	145/370 (39%)
		LPLAT_LCLAT1-like	75..271	CDD:153252	80/195 (41%)
		Acyltransf_C	258..336	CDD:292694	31/77 (40%)
Agpat4	XP_006523408.3	PLN02380	100..406	CDD:178006	134/316 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848229
Domainoid	1	1.000	125	1.000	Domainoid score	I5440
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	289	1.000	Inparanoid score	I2791
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG51956
OrthoDB	1	1.010	-	-		D482283at33208
OrthoFinder	1	1.000	-	-		FOG0001449
OrthoInspector	1	1.000	-	-		mtm8818
orthoMCL	1	0.900	-	-		OOG6_103673
Panther	1	1.100	-	-	LDO	PTHR10983
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3473
SonicParanoid	1	1.000	-	-		X1337
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.800