DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Agpat3 and Aup1

DIOPT Version :9

Sequence 1:	NP_001246793.1	Gene:	Agpat3 / 39820	FlyBaseID:	FBgn0036623	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001073368.1	Gene:	Aup1 / 680423	RGDID:	1591777	Length:	410	Species:	Rattus norvegicus

Alignment Length:	394	Identity:	67/394 - (17%)
Similarity:	115/394 - (29%)	Gaps:	164/394 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LCIALTFFTS-GLCINFIQLL--MHVFIKPI---DKRLFRKLMYYACYSLYSQLIFVSDWYAGSK 84
            |.:||..:.. |||:..::|.  :|||:...   |..|.|.::...|..|              .
  Rat    24 LLLALLLYAPVGLCLLVLRLFLGLHVFLVSCALPDSVLRRFVVRTMCAVL--------------G 74

  Fly    85 MTVYMDKEDFEKHAGKEHVLLIMNHKYEID-----------------------WLNGWM-ICEKL 125
            :....:......|..:   :||.||....|                       |..|:| :..::
  Rat    75 LVARQEDSGLRDHRVR---VLISNHVTPFDHNIVNLLTTCSTPLLNSPPSFVCWSRGFMEMDRRV 136

  Fly   126 GVLGNCKAY-AKKAIRYVPII------------------GWGWWLAEFVFLNRNFDQDKTIITEQ 171
            .::.:.|.: |...:...|::                  .|.:.:.:.|       |..|:..::
  Rat   137 ELVESLKKFCASTRLPPTPLLLFPEEEATNGREGLLRFSSWPFSIQDVV-------QPLTLQVQR 194

  Fly   172 LKVVFSYPDPTWL--LL-------------------------NAE----------------GTRF 193
            ..|..:..|.:|:  ||                         |.|                |||.
  Rat   195 PLVSVTVSDASWVSELLWSLFVPFTVYQVRWLHPIRRQLGEENEEFALRVQQLVAKELGQIGTRL 259

  Fly   194 TPAKHEASVKFAQERGMTVLKHHLIPRTKGFTASLAPIRGLCPVIYDINLAYRPTDKTPAT--ML 256
            |||.....:|         .:.|...|.:...:|.                  |:..:|::  .|
  Rat   260 TPADKAEHMK---------RQRHPRLRPQSVQSSF------------------PSPPSPSSDVQL 297

  Fly   257 SLL--HGKSVEPHLLMRRIPLEQVPEDEKEAAAWLQNLFVEKDKIIDSFLETGSFFK----TSGI 315
            ::|  ..|.|.||     :||..:..|......        .|..|.:.||....|.    |.|.
  Rat   298 TILAQRVKEVLPH-----VPLNVIQRDLARTGC--------VDLTITNLLEGAVAFMPEDVTEGS 349

  Fly   316 KEVP 319
            :.:|
  Rat   350 QSLP 353

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat3	NP_001246793.1	PLN02380	23..387	CDD:178006	67/394 (17%)
		LPLAT_LCLAT1-like	75..271	CDD:153252	41/285 (14%)
		Acyltransf_C	258..336	CDD:292694	16/68 (24%)
Aup1	NP_001073368.1	LPLAT	66..264	CDD:302626	31/221 (14%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	259..293		9/60 (15%)
		CUE_AUP1	300..340	CDD:270603	12/52 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	348..367		2/6 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900