DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Agpat3 and Agpat3

DIOPT Version :9

Sequence 1:	NP_001246793.1	Gene:	Agpat3 / 39820	FlyBaseID:	FBgn0036623	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001099848.1	Gene:	Agpat3 / 294324	RGDID:	1305787	Length:	376	Species:	Rattus norvegicus

Alignment Length:	382	Identity:	154/382 - (40%)
Similarity:	236/382 - (61%)	Gaps:	11/382 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 MGSLEKLKQLRLIHLCIALTFFTSGLCINFIQLLMHVFIKPIDKRLFRKLMYYACYSLYSQLIFV 76
            ||.|..||...::||.|...|..|||.|||.||.. :.:.||.|.|:|::.....|||:|||:.:
  Rat     1 MGLLAYLKTQFVVHLLIGFVFVVSGLIINFTQLCT-LALWPISKNLYRRINCRLAYSLWSQLVML 64

  Fly    77 SDWYAGSKMTVYMDKEDFEKHAGKEHVLLIMNHKYEIDWLNGWMICEKLGVLGNCKAYAKKAIRY 141
            .:|::.::.|::.|:... .|.|||||::|:||.:|||:|.||.:||:.||||:.|..||:.:.|
  Rat    65 LEWWSCTECTLFTDQATV-NHFGKEHVVVILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLY 128

  Fly   142 VPIIGWGWWLAEFVFLNRNFDQDKTIITEQLKVVFSYPDPTWLLLNAEGTRFTPAKHEASVKFAQ 206
            ||:|||.|:..|.||..|.:::|:..:.|.|:.:.:||:..|.||..||||||..||..|::.|.
  Rat   129 VPLIGWTWYFLEIVFCKRKWEEDRDTVIEGLRRLANYPEYMWFLLYCEGTRFTETKHRVSMEVAA 193

  Fly   207 ERGMTVLKHHLIPRTKGFTASLAPIRGLCPVIYDINLAYRPTDKTPATMLSLLHGKSVEPHLLMR 271
            .:|:..||:||:|||||||.::..:||....|||:.|.:| .:|.| ::|.:|:||..|..:.:|
  Rat   194 SKGLPPLKYHLLPRTKGFTTAVQCLRGTVAAIYDVTLNFR-GNKNP-SLLGILYGKKYEADMCVR 256

  Fly   272 RIPLEQVPEDEKEAAAWLQNLFVEKDKIIDSFLETGSFFKTSGIKEVPAYVNKRRLCSLVNFVCW 336
            |.|||.:|.||..||.||..|:.|||.:.:.:.::|.|   .|.:..||    ||..:|:||:||
  Rat   257 RFPLEDIPADETGAAQWLHKLYQEKDALQEMYKQSGVF---PGEQIKPA----RRPWTLLNFLCW 314

  Fly   337 AVFSLSCIFYYVITSLLAANWTAFITALSVLGLFYWLMGQAINKTQISKASNYGSSK 393
            |.|.||.:|.:|:....:.:....:|.|..:|...:.:.:.|..|:|.|.|:||:.:
  Rat   315 ATFLLSPLFSFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQE 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat3	NP_001246793.1	PLN02380	23..387	CDD:178006	146/363 (40%)
		LPLAT_LCLAT1-like	75..271	CDD:153252	82/195 (42%)
		Acyltransf_C	258..336	CDD:292694	30/77 (39%)
Agpat3	NP_001099848.1	PLN02380	12..325	CDD:178006	131/312 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351808
Domainoid	1	1.000	129	1.000	Domainoid score	I5116
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10591
Inparanoid	1	1.050	295	1.000	Inparanoid score	I2662
OMA	1	1.010	-	-		QHG51956
OrthoDB	1	1.010	-	-		D482283at33208
OrthoFinder	1	1.000	-	-		FOG0001449
OrthoInspector	1	1.000	-	-		mtm9064
orthoMCL	1	0.900	-	-		OOG6_103673
Panther	1	1.100	-	-	O	PTHR10983
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1337
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770