DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Agpat3 and LPCAT4

DIOPT Version :9

Sequence 1:	NP_001246793.1	Gene:	Agpat3 / 39820	FlyBaseID:	FBgn0036623	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_705841.2	Gene:	LPCAT4 / 254531	HGNCID:	30059	Length:	524	Species:	Homo sapiens

Alignment Length:	151	Identity:	34/151 - (22%)
Similarity:	48/151 - (31%)	Gaps:	59/151 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 GVLGNCKAYAK--------------KAIRY---VPIIGWGW---------WLAEFVFLNRNFDQD 164
            |...|.||..|              ..|||   :....|.|         ||..        .|.
Human   204 GTCSNKKALLKFKPGAFIAGVPVQPVLIRYPNSLDTTSWAWRGPGVLKVLWLTA--------SQP 260

  Fly   165 KTIITEQLKVVFSYPDPTWLLLNAEGTRFTPAKHEASVK--FAQERGMTVLKHHLIPRTK-GFTA 226
            .:|:..:...|: :|.|       |.:| .|..:..:|:  .||..|        ||.|: .|..
Human   261 CSIVDVEFLPVY-HPSP-------EESR-DPTLYANNVQRVMAQALG--------IPATECEFVG 308

  Fly   227 SLAPIRGLCPVIYDINLAYRP 247
            ||..|     |:..:.:|..|
Human   309 SLPVI-----VVGRLKVALEP 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat3	NP_001246793.1	PLN02380	23..387	CDD:178006	34/151 (23%)
		LPLAT_LCLAT1-like	75..271	CDD:153252	34/151 (23%)
		Acyltransf_C	258..336	CDD:292694
LPCAT4	NP_705841.2	LPLAT_LPCAT1-like	109..306	CDD:153253	27/126 (21%)
		HXXXXD motif	129..134
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	489..524
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810