DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Agpat3 and SPBC428.14

DIOPT Version :9

Sequence 1:	NP_001246793.1	Gene:	Agpat3 / 39820	FlyBaseID:	FBgn0036623	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_595192.1	Gene:	SPBC428.14 / 2540846	PomBaseID:	SPBC428.14	Length:	350	Species:	Schizosaccharomyces pombe

Alignment Length:	381	Identity:	96/381 - (25%)
Similarity:	176/381 - (46%)	Gaps:	72/381 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MVVHKNSFVIKMGSLEKLKQLRLIHLCIA---LTFFTS---GLCINFIQLLMHVFIKPIDKRLFR 59
            :.:.|.||:                ||:|   :|.:||   |..:.|           ::|.|:.
pombe     5 IAIRKYSFI----------------LCLAVGSVTIYTSEVIGTPLYF-----------VNKELYN 42

  Fly    60 KLMYYACYSLYSQLIFVS--DWYAGSKMTV----------YMDKEDFEKHAGKEHVLLIMNHKYE 112
            |  |.|....::.::|.:  ..::.:.:|:          |:|:....:....|..::|.||:..
pombe    43 K--YIAFTKSFAGILFTALVQLFSPTPVTLTYDPELRNLFYLDRNGCLETIAAERNIVIANHQLY 105

  Fly   113 IDWLNGWMICEKLGVLGNCKAYAKKAIRYVPIIGWGWWLAEFVFLNRNFDQDKTIITEQLKVVFS 177
            .||:..|.:.......|:.....|.:::::|:||||..|..|:||:|.:|:|...::...|.:.:
pombe   106 SDWMYVWWLSYTAKQHGHVYIMLKNSLKWLPVIGWGMQLFRFIFLSRKWDKDYETMSRHFKFIRN 170

  Fly   178 YPDPTWLLLNAEGTRFTPAKHEASVKFAQERGMTVLKHHLIPRTKGFTASLAPIRGLCPVIYDIN 242
            ..|...|:|..|||....:.::.|..:|.:.|:.:.||.::||.:|...|::.:|.....:||..
pombe   171 VRDSVSLILFPEGTNLVESTYQRSRVYADKIGVKMPKHLMLPRVRGLFYSISQLRDSMTYLYDYT 235

  Fly   243 LAYRPTDKTP----ATMLSL----LHGKSVEP-HLLMRRIPLEQVPEDEKEAAAWLQNLFVEKDK 298
            ..:  :|.:|    |...||    ..|..::. |:.:||.|:.::|.:|.:...||...:.||||
pombe   236 FYF--SDPSPKKYAADAFSLPKLFFEGVPIKRLHIHVRRFPISEIPTEEDQFTDWLYQRWYEKDK 298

  Fly   299 IIDSFLETGSFFKTSGIKEVPAYVN-KRRLCSLVNFVCWAVFSL-SCIFYYVITSL 352
            :||:.||||:|   .|.|::...|. |.||         .:.|| |.:|..::..|
pombe   299 LIDTLLETGNF---PGPKKLHTTVRLKHRL---------EILSLFSVLFTCIVAGL 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Agpat3	NP_001246793.1	PLN02380	23..387	CDD:178006	93/359 (26%)
		LPLAT_LCLAT1-like	75..271	CDD:153252	51/216 (24%)
		Acyltransf_C	258..336	CDD:292694	27/83 (33%)
SPBC428.14	NP_595192.1	PlsC	23..307	CDD:223282	75/298 (25%)
		LPLAT_LCLAT1-like	57..271	CDD:153252	50/215 (23%)
		Acyltransf_C	257..335	CDD:292694	29/89 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	66	1.000	Domainoid score	I2791
eggNOG	1	0.900	-	-		E1_COG0204
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I1478
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001449
OrthoInspector	1	1.000	-	-		otm47192
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3473
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.890